Extracorporeal blood treatment apparatus, methods, and systems to perform an extracorporeal blood treatment using an organic filter operable to perform the functions of an organ are described herein. The extracorporeal blood treatment apparatus includes a treatment set, a high flow pump, a first low flow pump, and a second low flow pump, and a computing apparatus operatively coupled to the extracorporeal blood treatment apparatus. The computing apparatus may be configured to perform an extracorporeal blood treatment using the extracorporeal blood treatment apparatus and the organic filter.

A method for onsite hemorrhage control in trauma patients using a portable rapid autotransfusion device can involve recovering a first portion of patient blood from an extravascular space into a fluid reservoir of the device. A negative internal pressure can be applied to the blood. The blood can be conditioned, such as by oxygenating and removing carbon dioxide. The conditioned blood can be returned to the patient intravenously at a rate that matches the rate of blood recovery, ensuring that the net volume of returned blood is maintained substantially equal to the net volume of removed blood.

A blood pump-oxygenator system comprises a blood pump, oxygenator, blood flow inlet, and blood flow outlet forming a circuit operable as a cardiopulmonary bypass system for extracorporeal processing of the patient's blood, wherein the first blood pump conveys blood through the circuit from the patient into the blood flow inlet, through the oxygenator and out of the blood flow outlet back into the patient. The system further comprises a recirculation loop between the blood flow inlet and blood flow outlet that accommodates the first blood pump and oxygenator, wherein the first blood pump circulates at least part of the blood in the circuit through the recirculation loop such that blood passes through the oxygenator multiple times and is repeatedly subject to exchange of O.sub.2 and CO.sub.2 within the oxygenator. A valve between the recirculation loop and blood flow outlet controls an amount of blood flowing through the recirculation loop.

A blood pump-oxygenator system for increasing perfusion and oxygen level in a patient comprises a blood flow inlet and outlet forming a circuit operable as a cardiopulmonary bypass system for extracorporeal processing of blood, a first blood pump and first oxygenator. The first blood pump conveys blood through the circuit from the patient into the blood flow inlet, through the first oxygenator and out of the blood flow outlet back into the patient. The system further comprises a second blood pump and second oxygenator. The second blood pump conveys blood through the circuit from the patient into the inlet, through the second oxygenator and out of the outlet back into the patient. A pump control unit controls the first and second pumps to increase or decrease blood flow rate through the respective oxygenator to vary a ratio of flow rates of blood through the first and second oxygenators.