H05H3/04

MULTIPLE LAMINAR FLOW-BASED PARTICLE AND CELLULAR SEPARATION WITH LASER STEERING

The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.

Device and method for interaction between an agile laser beam and a hyperfine energy transition of a chemical species

Disclosed is a device for interaction between a laser beam and a hyperfine energy transition of a chemical species. The device further includes an electro-optic modulator with a single sideband with an input optical waveguide suitable for receiving a source laser beam and an output optical waveguide suitable for generating an output laser beam and an electronic system suitable for generating and applying, simultaneously, a first modulated electrical signal, sin(Ω.sub.1t)) to a first hyperfrequency pulse on a first high-frequency electrode of the electro-optic modulator and, respectively, another modulated electrical signal, cos(Ω.sub.1t)) to the first pulse on another high-frequency electrode of the electro-optic modulator, in such a way as to frequency-switch the output laser beam to a first optical frequency offset from the first pulse with respect to the initial optical frequency.

Device and method for interaction between an agile laser beam and a hyperfine energy transition of a chemical species

Disclosed is a device for interaction between a laser beam and a hyperfine energy transition of a chemical species. The device further includes an electro-optic modulator with a single sideband with an input optical waveguide suitable for receiving a source laser beam and an output optical waveguide suitable for generating an output laser beam and an electronic system suitable for generating and applying, simultaneously, a first modulated electrical signal, sin(Ω.sub.1t)) to a first hyperfrequency pulse on a first high-frequency electrode of the electro-optic modulator and, respectively, another modulated electrical signal, cos(Ω.sub.1t)) to the first pulse on another high-frequency electrode of the electro-optic modulator, in such a way as to frequency-switch the output laser beam to a first optical frequency offset from the first pulse with respect to the initial optical frequency.

DEVICE AND METHOD FOR INTERACTION BETWEEN AN AGILE LASER BEAM AND A HYPERFINE ENERGY TRANSITION OF A CHEMICAL SPECIES
20210368612 · 2021-11-25 ·

Disclosed is a device for interaction between a laser beam and a hyperfine energy transition of a chemical species. The device further includes an electro-optic modulator with a single sideband with an input optical waveguide suitable for receiving a source laser beam and an output optical waveguide suitable for generating an output laser beam and an electronic system suitable for generating and applying, simultaneously, a first modulated electrical signal, sin(Ω.sub.1t)) to a first hyperfrequency pulse on a first high-frequency electrode of the electro-optic modulator and, respectively, another modulated electrical signal, cos(Ω.sub.1t)) to the first pulse on another high-frequency electrode of the electro-optic modulator, in such a way as to frequency-switch the output laser beam to a first optical frequency offset from the first pulse with respect to the initial optical frequency.

DEVICE AND METHOD FOR INTERACTION BETWEEN AN AGILE LASER BEAM AND A HYPERFINE ENERGY TRANSITION OF A CHEMICAL SPECIES
20210368612 · 2021-11-25 ·

Disclosed is a device for interaction between a laser beam and a hyperfine energy transition of a chemical species. The device further includes an electro-optic modulator with a single sideband with an input optical waveguide suitable for receiving a source laser beam and an output optical waveguide suitable for generating an output laser beam and an electronic system suitable for generating and applying, simultaneously, a first modulated electrical signal, sin(Ω.sub.1t)) to a first hyperfrequency pulse on a first high-frequency electrode of the electro-optic modulator and, respectively, another modulated electrical signal, cos(Ω.sub.1t)) to the first pulse on another high-frequency electrode of the electro-optic modulator, in such a way as to frequency-switch the output laser beam to a first optical frequency offset from the first pulse with respect to the initial optical frequency.

Non-destructive inspection system comprising neutron radiation source and neutron radiation method

A non-destructive inspection system 1 includes a neutron radiation source 3 capable of emitting neutrons N, and a neutron detector 14 capable of detecting neutrons Nb produced via an inspection object 6a among neutrons N emitted from the neutron radiation source 3. The neutron radiation source 3 includes a linear accelerator 11 capable of emitting charged particles P accelerated; a first magnet section 12 including magnets 12a and 12b facing each other, the magnets 12a and 12b being capable of deflecting the charged particles P in a direction substantially perpendicular to a direction of emission of the charged particles P from the linear accelerator 11; and a target section 13 capable of producing neutrons N by being irradiated with the charged particles P that have passed through the first magnet section 12.

Non-destructive inspection system comprising neutron radiation source and neutron radiation method

A non-destructive inspection system 1 includes a neutron radiation source 3 capable of emitting neutrons N, and a neutron detector 14 capable of detecting neutrons Nb produced via an inspection object 6a among neutrons N emitted from the neutron radiation source 3. The neutron radiation source 3 includes a linear accelerator 11 capable of emitting charged particles P accelerated; a first magnet section 12 including magnets 12a and 12b facing each other, the magnets 12a and 12b being capable of deflecting the charged particles P in a direction substantially perpendicular to a direction of emission of the charged particles P from the linear accelerator 11; and a target section 13 capable of producing neutrons N by being irradiated with the charged particles P that have passed through the first magnet section 12.

Downhole neutron generators and methods to auto tune downhole neutron generators
11395399 · 2022-07-19 · ·

Downhole neutron generators, downhole logging tools that utilize neutron generators, and methods to auto tune downhole neutron generators are disclosed. While a neutron generator is deployed in a borehole of a wellbore, the method includes determining whether an oscillation cycle of an ion beam current generated by the neutron generator is stable. After a determination that the oscillation cycle of the ion beam current is stable, the method includes determining proportional, integral, and derivative parameters of a proportional-integral-derivative controller that is operable to adjust an amount of power supplied to generate ions. The method further includes adjusting a replenish voltage of a replenish power supply of the neutron generator based on the proportional, integral, and derivative parameters.

Downhole neutron generators and methods to auto tune downhole neutron generators
11395399 · 2022-07-19 · ·

Downhole neutron generators, downhole logging tools that utilize neutron generators, and methods to auto tune downhole neutron generators are disclosed. While a neutron generator is deployed in a borehole of a wellbore, the method includes determining whether an oscillation cycle of an ion beam current generated by the neutron generator is stable. After a determination that the oscillation cycle of the ion beam current is stable, the method includes determining proportional, integral, and derivative parameters of a proportional-integral-derivative controller that is operable to adjust an amount of power supplied to generate ions. The method further includes adjusting a replenish voltage of a replenish power supply of the neutron generator based on the proportional, integral, and derivative parameters.

Multiple laminar flow-based particle and cellular separation with laser steering

The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.