A failsafe system for a medical fluid procedure, comprising a medical fluid processing apparatus comprising a sealer and a programmable controller driven by software, wherein the programmable controller is programmed to recognize a failure event from input from hardware components of the medical fluid processing apparatus. The system also comprises a disposable fluid circuit configured to associate with the medical fluid processing apparatus and comprising a tubing segment configured to fit within the sealer. The programmable controller is configured to seal the tubing segment by activating the sealer surrounding the tubing segment in response to an occurrence of the failure event.

A connection apparatus for sealing to a pathway of a mounting structure includes a body; and a port including a threaded portion extending from the body and a non-threaded portion extending from the threaded portion, the non-threaded portion carrying a gasket, the gasket positioned along the non-threaded portion such that the mounting structure to which the connection apparatus is mounted contacts the gasket prior to the threaded portion engaging a mating threaded portion of the mounting structure, the port providing fluid communication between the body and the pathway of the mounting structure. The body may be that of a valve that supplies any of air, water or oil as an operating fluid to, for example, inlet and outlet valves and a pump chamber of a medical fluid pump of a medical fluid delivery machine.

The disclosure relates to a method for checking a connection between a compressed air outlet of a blood treatment apparatus and a pressure measuring line of an extracorporeal blood tubing set. The methods disclosed include providing a blood treatment apparatus having a compressed air line. A compressed air device is in fluid communication with the compressed air line for generating pressure within the compressed air line. A compressed air outlet is in fluid communication with both the compressed air line and an exterior of the blood treatment apparatus. The compressed air outlet is connectable with a pressure measuring line and a pressure sensor. The method also includes building up a pressure and an air flow in the compressed air line and/or at the compressed air outlet, measuring a pressure at the compressed air outlet or in the compressed air line, and evaluating an increase of the measured pressure.

A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.

The present invention relates to an apparatus for carrying out an apheresis treatment, wherein the apparatus has an extracorporeal circuit in which a regenerable single adsorber is located for separating substances from blood or for separating substances from plasma acquired by means of a plasma separator, wherein a line is provided for conducting the blood or the plasma which extends to the adsorber and via which blood or plasma is applied to the adsorber, wherein a reservoir is provided for receiving blood or plasma and is arranged upstream of the adsorber in the line or is in communication with the line upstream of the adsorber; and in that a controller or switching means is provided which is configured such that the reservoir is filled with blood or plasma and the application of blood or plasma to the adsorber is suppressed when the regeneration of the adsorber is carried out.

Connector assemblies and methods of replacing components in an extra-corporeal circuit (ECC) system are disclosed. A connector assembly for use in an ECC system includes a tubular body having an inner surface defining a lumen extending through the tubular body with the lumen extending along a longitudinal axis, a first connection interface in fluid communication with the lumen, second connection interface in fluid communication with the lumen, and a plurality of closure mechanisms, each closure mechanism being configured to occlude the lumen.

An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.

The present application refers to a heat transfer liquid for a temperature control device for human body temperature control during extracorporeal circulation, a temperature control device, the use of heat transfer liquid for extracorporeal circulation and a method of human body temperature control using a heat transfer liquid. The head transfer liquid consists of ethylene glycol or propylene glycol at about 25 volume-percent to about 35 volume-percent, hydrogen peroxide at 0.05 volume-percent or less and sterile, filtered and de-mineralized water as rest.

The flow path switching device includes: a body 100 including an outer cylinder 101 having four ports 111 and a plug 102 having two arc-shaped tunnel-like flow paths 121 each connecting adjacent two of four openings 102a formed in a side surface of the plug 102. The plug 102 is rotatable between a first position and a second position, the first position being a position in which one of the flow paths 121 connects adjacent two of the four ports 111 and the other flow path 121 connects the remaining two ports, and the second position being a position in which each of the flow paths connects adjacent two of the ports 111 which are not connected when the plug 102 is located at the first position.

A device for maintaining blood substantially free of biochemical coagulation and/or particulate precipitation, during extracorporeal treatment of blood is disclosed. Also disclosed are methods of using the device in an extracorporeal treatment of blood and kits comprising apparatus for performing such a method.