An apparatus, a system and methods are disclosed in relation to the configuration and compatibility of a removable delivery section of the apparatus, and delivering a substance via the apparatus to an animal. In an aspect, a hand held apparatus for delivering a substance to an animal includes a removable delivery section including a delivery arrangement adapted to deliver the substance to the animal; and a drive section including a drive arrangement adapted to actuate the delivery arrangement in a coupled condition in which the removable delivery section is coupled to the drive section. The delivery section includes an electronic device adapted to communicate with a control system associated with at least the drive section in the coupled condition, the electronic device being configurable so to be readable by the control system such that the control system is able to identify and operate the removable delivery section.

A connecting module is provided with a first connecting component, which has a first fluid channel and a first contact surface, a second connecting component, which has a second fluid channel and a second contact surface. One of the two contact surfaces is formed as an inner surface and the other of the two contact surfaces is formed as an outer surface which is complementary to the inner surface. The connecting module further includes a receiving sleeve with a first threaded section and a first connecting device for the first connecting component. The first connecting component has a second connecting device, which interacts with the first connecting device in such a way that the first connecting component is detachably connected to the receiving sleeve. The second connecting component has a second threaded section which is complementary to the first threaded section.

Described herein is a dispenser for dispensing fluid that, integrated into one hand piece, comprises a variable volume chamber with a plunger disposed within the chamber and a chamber inlet and outlet. The inlet and outlet communicate directly with a common chamber volume and the plunger translates in a linear direction relative to the chamber along a common longitudinal axis to expel fluid from the chamber (expel stroke) and/or draw fluid into the chamber (drawing stroke). The plunger is linked to a controller, a power source and a motor that drives translation movement of the plunger. The dispenser described herein offers a variety of advantages over the art including accurate dosing without the user having to manually regulate the dose amount—the amount to be dosed is related to the volume of fluid in the chamber which can be pre-set or varied automatically using sensors and controllers.

Injection device comprising an elongated body (1) with a hollow needle (8) at a distal end; a reservoir for an injection material to be delivered through the needle; a plunger (3) with a first force element (5) configured to provide an injection force to said injection material, and a distal element (10) attached to the distal end of the device thereby sealing a needle lumen, wherein the distal element comprises a tissue interface and a distal seal (11), and wherein the distal seal is penetrable by a distal tip of the needle by the application of pressure on a tissue surface with the distal end of the device, wherein the penetrated distal element becomes slidable on the needle to allow advancement of the needle into tissue, wherein the penetrated distal seal opens a path for flow or delivery of the injection material from the distal end of the needle.

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.

A dispensing device (1) for dispensing a fluid, preferably an injection syringe. The device comprises a main body (2) which has a longitudinal axis (A) and has a receiving space (3) for receiving the fluid, and a connection channel (4) communicates with the receiving space. The connection channel opens on a valve face (5) of the main body. The device comprises a movable flow control element (6) arranged on the main body. The flow control element has one or more flow channels (7) which open on a valve face (8) of the flow control element. The connection channel of the main body and the flow channels of the flow control element are fluidically connected to each other by relative movement of main body and flow control element. A sealing element (10) is arranged between the valve face of the main body and the valve face of the flow control element.

A device for administering a fluid can include a cylinder, a piston connected to a piston rod, and a tensioning device connected to the piston rod. In a dispensing procedure a ramp track is rotated until the roller runs over a transfer region and is accelerated toward the first plateau and, as a result, the piston is moved toward an open dispensing end. A motor is connected to the ramp via a coupling. To rotate the ramp, the coupling transmits torque provided by the motor in the first rotation direction and, in the process, provides a freewheel counter to the first rotation direction. The freewheel is configured such that it covers at least a rotation angle range which corresponds to the transfer region.

An injection apparatus for sequentially injecting a patient with at least two medicaments may include a hand-held unit comprising a grip for being held by an operator, a single needle, a base unit coupled to the hand-held unit via at least one connecting tube, at least two containers for holding medicaments removably coupled to the base unit, and at least one pump. The at least one connecting tube can be flexible enough to enable easy maneuvering of the hand-held unit and rigid enough to prevent widening of the tube due to inner pressure when medicaments pass from the containers to the hand-held unit. The injection apparatus can be used to administer the at least two medicaments sequentially at different injection points.

Wearable auto-injector devices, systems and methods prevent medication administration in a device-worn state using a mechanism that prevents administration medication or by making it impossible or operationally impractical to physical orient or align the device to achieve injection. The device includes a housing, an attachment component enabling the housing to be worn by a user, and a medication delivery system including a needle and a medication reservoir. An advancement system advances the needle into a user's skin and causes the medication to flow through the needle. Various advancement systems, error-reduction mechanisms, attachment alternatives, and optional monitoring and communications capabilities are disclosed.

A device and a method for adjustable quantitative injection of high-pressure gas are provided, wherein the gas may have a pressure of 5 MPa or more than 5 MPa. The gas may be directly communicated with a gas tank in the mechanism or an external gas source, flows through corresponding valves, and is charged into a predetermined or adjustable reservoir. Alternatively, the valve may be time-controllable, and does not need the reservoir. The gas is ejected through a nozzle selected based on depth or range of injection, wherein a one-way valve is disposed between the nozzle and the body to prevent contamination due to backflow. The manipulator can exert an appropriate force onto a target portion of a human for gas injection, and when the injection is done, a biasing member can automatically return the mechanism to its original state, ready for the next injection.