A device for administering a fluid can include a cylinder, a piston connected to a piston rod, and a tensioning device connected to the piston rod. In a dispensing procedure, a ramp track is rotated until a roller runs over a transfer region and is accelerated toward the first plateau and, as a result, the piston is moved toward an open dispensing end. The ramp track runs on the face side of a wall extending along a circular path. A cover engages over the ramp track, the driver and the roller and has at least one scraper extending counter to the first direction and extending within the wall as far as the inner side of the wall, and thus scrapes off lubricant located on the inner side from the inner side.

A high pressure delivery system for delivering a medicament, comprising a first chamber for storing a supply of the medicament, a gear pump assembly in fluid communication with the first chamber, said gear pump assembly having a dose inlet and a dose discharge, said dose inlet having a larger diameter than said dose discharge to provide a high pressure discharge, and a fluid connection path in fluid communication with the gear pump assembly for delivering the medicament to a high pressure area.

The invention includes a device having a chamber within a syringe. A fluid passageway extends through a syringe piston. A valve is associated with the passageway controlling fluid passage through the piston. The invention includes a piercing structure having a head segment and a body portion, with a channel through the body portion and through at least one surface of the head without passing through the tip. In another aspect the invention encompasses a method of preparing an agent for administration to an individual. A first component is provided within a syringe and a second component is provided within a vial. A closed valve is associated with a fluid passageway between the vial and the syringe barrel through a piston. Valve repositioning allows fluid passage and sliding of the piston joins the first and second components. Repeated sliding of the piston mixes the components to produce the medication agent.

Method and device to inject fluid into animals through a sterile needle, requiring control of fluid volume, flow rate of injection, accuracy of injection site, depth of penetration, disposal administration of consumable materials and quality control of the fluid and fluid administration using a portable applicator controlled by an external software controlled pump and controller system used in administering fluid medications, organic castration compounds and other fluids to be administered to live animals.

Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.

Injection device comprising an elongated body (1) with a hollow needle (8) at a distal end; a reservoir for an injection material to be delivered through the needle; a plunger (3) with a first force element (5) configured to provide an injection force to said injection material, and a distal element (10) attached to the distal end of the device thereby sealing a needle lumen, wherein the distal element comprises a tissue interface and a distal seal (11), and wherein the distal seal is penetrable by a distal tip of the needle by the application of pressure on a tissue surface with the distal end of the device, wherein the penetrated distal element becomes slidable on the needle to allow advancement of the needle into tissue, wherein the penetrated distal seal opens a path for flow or delivery of the injection material from the distal end of the needle.

In one aspect, a connector assembly includes a delivery conduit defining a conduit lumen and a securable connector configured to secure the delivery conduit to a medical device hub defining a medical device hub lumen. The conduit lumen includes a constant diameter region along a portion of the delivery conduit and a transition region extending from the delivery conduit to the distal end. A transition region diameter of the transition region gradually increases from the constant diameter region to a distal end of the delivery conduit. The securable connector is coupled to an outer surface of the delivery conduit and is slidable along a portion thereof. The securable connector is configured to receive the medical device hub. The securable connector is secured relative to the delivery conduit so as to fluidically couple the conduit lumen with the medical device hub lumen.

An automatic jet injector for administering tissue is provided with a housing including a grip and a pushbutton; a syringe positioning device on a top of the housing and including an intermediate support and a rear pushing board having a lower through hole and a threaded hole under the through hole; a power source in the housing and including a power supply configured to supply power to the power source by pressing the pushbutton; a fastening member in the housing and being adjacent to a rear end of the housing; a positioning member being adjacent to the power source; a reciprocating screw having a front end operatively connected to the power source and a rear end fastened in the fastening member; a rod having a front end fastened in the positioning member and a rear end fastened in the fastening member; and a control device.

Multiphase microspheres for radioembolization include two-phase microspheres and three-phase microspheres prepared by a microfluidic process. The multiphase microspheres include a primary phase and a first secondary phase surrounded by the primary phase. The primary phase includes a first resin. The first secondary phase includes a second resin and at least one of a radioactive isotope or a compound including at least one radioactive element. Three-phase microspheres additionally include a second secondary phase discrete from the first secondary phase and also surrounded by the primary phase. The second secondary phase may be a gas such as air. The microspheres may be formed by a microfluidic process.

A medical device and system for the administration of a medical substance or for dosing body fluids comprising a rotor, rotating around an axis X-X, operatively connected to an injection device of said medical substance, and a rotor locking/unlocking device mechanically separate from the rotor and integral in rotation therewith. The locking/unlocking device comprises, in one piece, a disc, centered with respect to said axis X-X, from which a plurality of flexible fins radially unravel. The flexible fins are configured to flex around transverse hinges at a connection portion with the disc, and are angularly spaced so as to define gaps between adjacent pairs of fins which prevent interferences between adjacent fins in the respective flexing movement. The flexible fins are associated with ferromagnetic means for the operation of the same fins and locking/unlocking means of the rotation of the disc. The disc and fins are formed from a single plastic body.