Apparatuses and methods for delivering a fluid, including a viscous fluid. These apparatuses may include a fluid reservoir, two or more piston chambers, a manifold, a delivery port, and a drive assembly and may be configured to inject either a predetermined amount of fluid or a continuous stream of fluid. These apparatuses may also be configured to switch between filling, injection and aspiration modes. These apparatuses may generally be hand-held and lightweight and may provide a significant mechanical advantage to the user.

A medicament delivery device system for delivery of a medicament from a cartridge (10). The system comprises a first container (11) for storage of a first substance, a second container (12) received in the first container (11) for storage of a second substance, and valve means (68) for closing a distal end of the second container (12). The system further comprises a disposable cassette (102) and a reusable firing unit (200). The cassette (102) has a body (104) for receiving the cartridge (10), and a mixing element (148) for displacing the second substance into the first chamber (16) in a mixing stroke, to mix with the first substance to form the medicament. The firing unit (200) comprises a drive element (208) for expelling the medicament from the first chamber (16) in a delivery stroke and a trigger arrangement (240) for initiating the delivery stroke.

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.

An auto injector for administering injection of a medicament from a cartridge containing the medicament, includes a housing, a cartridge receiver with a cartridge receiver compartment configured to receive a cartridge assembly including at least one cartridge retention member when the cartridge assembly is inserted through a cartridge receiver opening along a longitudinal axis in a receiving direction, an elongated ejector including an ejector support face for supporting the cartridge or the cartridge assembly and a longitudinal ejector slot extending towards the ejector support face from an ejector rest portion, wherein the elongated ejector is suspended to move along the longitudinal direction and is spring-loaded in the direction opposite of the receiving direction, and an ejector lock supported for turning at least a fraction of a revolution and maintained in a longitudinal position relative to the housing.

An apparatus includes a housing, a carrier, and an expandable assembly. The housing defines an opening configured to selectively place a gas chamber of the housing in fluid communication with an exterior volume. The carrier is movably disposed within the housing and is coupled to a medicament container. A proximal surface of the carrier defines a portion of a boundary of the gas chamber. The expandable assembly has a first member and a second member. The first member is coupled to an elastomeric member disposed within the medicament container, and the second member includes a valve portion. The expandable assembly transitions from a collapsed configuration to an expanded configuration when the elastomeric member moves within the medicament container. The valve portion moves relative to the opening when the expandable assembly transitions from the first to the second configuration, placing the gas chamber in fluid communication with the exterior volume.

A reciprocating medicament mixing and injector system, where the energy provided to transfer medicament components back and forth between containers or cartridges can be redirected to deliver the mixed medicament components. In one embodiment the energy source is a pressurized gas chamber, in another, it is constant force spring, and in another it is a compression spring.

A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

A mixing and/or reconstitution system reduces the possibility of user error and provides a well mixed and/or reconstituted drug in a short time. The system comprises a device containing a first material within a first chamber, a housing, and a plunger, the plunger comprising a second chamber containing a second material, wherein one of the first and the second material is a fluid, and a movable element with an electric, magnetic, or paramagnetic characteristic, wherein the second chamber is initially closed; and a base unit comprising a recess for accommodation of the device, a control unit, and an electromagnetic unit which is adapted to produce an electromagnetic field penetrating the recess, wherein the control unit can electrically operate the electromagnetic unit such that the element contained in the second chamber moves in a direction of the device determined by the electromagnetic field and fluidly communicates the first and second chambers.

Provided is a sequential injection module included in a skin treatment device, the module sequentially injecting a gas and a drug into the skin of a user through one needle. The sequential injection module comprises: a supply port for supplying each of gas and a drug; an output port for discharging each of same; and a channel control part for forming, therein, either a gas flow channel or a drug flow channel by means of the pressure of the gas and drug to be supplied.

A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.