An apparatus includes a housing, an energy storage member, a carrier, a medicament container, and a delivery control mechanism. The housing defines a gas chamber configured to receive pressurized gas from the energy storage member to pressurize the gas chamber. The carrier has a proximal surface that defines a portion of the gas chamber. The medicament container is coupled to the carrier and has a distal end portion coupled to a delivery member. The medicament container contains a medicament and includes an elastomeric member that seals the medicament within the medicament container. The delivery control mechanism is coupled to a proximal end portion of the medicament container and includes a flow restriction member for regulating a pressure supplied by the gas chamber and entering into the medicament container that acts on the elastomeric member.

A device (1) for dispensing a substance to a patient comprising a cylindrical first container (2) containing the substance and a second container (3) containing a liquid. The device further comprises an injection device (4) and transfer mechanism (5) for transferring the liquid from the second container (3) to the first container (2) and from the first container (2) to the injection device (4). The first container (2) has a connection element (7) and a plunger (9) that can be moved between the first (6) and second ends (8). By moving the plunger (9) towards the first end (6), liquid contained therein can be dispensed via the injection device (4). The injection device (4) comprises a piercing cannula (15) and an indwelling cannula (16). In an initial position, a distal end region of the piercing cannula (15) extends coaxially in the interior of the indwelling cannula (16).

The present disclosure relates to a safety mechanism (27) for a medicament delivery device for preventing activation thereof in the event of mechanical shock. The safety mechanism (27) comprises a medicament delivery member sleeve (7), a proximal flange (9) provided at the proximal end of the medicament delivery member sleeve (7), which proximal flange (9) has a first radially flexible arm (9a) extending longitudinally in the distal direction, a housing (3) having a central proximal opening (3a) arranged to receive a distal portion of the medicament delivery member sleeve (7), wherein the medicament delivery member sleeve (7) is axially displaceable inside the housing (3) from an extended position to a retracted position relative to the housing (3), and a cover (5) having a distal opening (5a) forming a channel arranged to receive the medicament delivery member sleeve (7) and the housing (3). The housing (3) has a proximal portion (3b) arranged between the first radially flexible arm (9a) and the outer surface of the medicament delivery member sleeve (7) when the medicament delivery member sleeve (7) is displaced from the extended position towards the retracted position. The channel is dimensioned such that, when the housing (3) is received by the cover (5), there is a radial distance between the inner surface of the cover (5) and the outer surface of the proximal portion (3b) which is less than a radial dimension of the first radially flexible arm (9a), preventing the medicament delivery member sleeve (7) from obtaining its retracted position.

The present disclosure relates to a medicament delivery device comprising a housing, a reservoir for medicament disposed in the housing and a dispensing member. The dispensing member is moveable relative to the housing from a first position to a second position to dispense medicament from the reservoir when the reservoir contains medicament. The medicament delivery device further comprises first and second biasing members. The first biasing member is configured to urge the dispensing member from the first position to an intermediate position. The second biasing member is configured to urge the dispensing member from the intermediate position to the second position.

An autoinjector includes a rear body assembly (10) connected to a front body assembly, wherein the rear body assembly (10) contains a drive mechanism (60 . . . ) and the front body assembly contains a syringe (13) or cartridge with a needle at its forward end, the front body assembly including a viewing window (22) through which at least part of the contents of the syringe (13) or cartridge are visible, a removable cap (14) fitted to the forward end of the front body assembly the rear body assembly and the removable cap having respective aligned cut-away regions together defining a frame for the viewing window. Also disclosed is a modular scheme which uses a common platform for the provision of a range of autoinjectors of different fill volumes, with only the length of the plunger (60), and the axial extent of the cut out varying between different versions.

An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case arranged to be held by a user, a tubular chassis telescoped in the case and biased against the case so as to protrude from the case. The injector also includes a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe. A trigger button is distally arranged in or on the case, wherein the trigger button is initially coupled to the case in a manner to protrude distally from the case and interlocked to the chassis in a manner preventing the trigger button from disengaging the case.

An automatic mixing device, an actuating device removably mounted to the automatic mixing device and a retractable syringe having the automatic mixing device are provided. The actuating device has an initially compressed spring and a trigger member that initiates spring decompression to drive depression of a mixing plunger of the automatic mixing device. A seal located in the outer chamber is capable of axial movement upon depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in an inner barrel to a second position intermediate the apertures and vents in an outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in an inner chamber of the inner barrel. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction.

A skin-patch type medicament delivery device (10, 30, 50) comprises a housing (11) containing a medicament delivery mechanism (12) including an injection needle (13). An adhesive surface (19) is provided for securing the housing (11) to a patient's skin during a medicament delivery process. A sterilizing mechanism is connected to the housing (11) and thus integrated into the device, and comprises a pad (18) impregnated with sterilizing agent which contacts the skin once the housing (11) is secured to a patient, and which can, respectively has to be moved in a swiping action across the injection site to sterilize the latter before the needle insertion and drug administration can be performed.

Systems and methods for monitoring an operational state and/or a fill status of a drug container of a drug delivery device are provided. The drug container can hold a liquid drug. A plunger can be positioned within the drug container. A drive system can advance the plunger to expel the liquid drug from the container. A monitoring system can detect a movement and/or a position of the plunger and/or any component coupled to the plunger. The detection can enable determination of an amount of liquid drug that has been expelled and/or an amount of liquid drug remaining in the drug container. Dosing rates, flow rates, and dosage completion can also be determined.

A device that prevents the accidental activation and lockout of an autoinjector. In illustrative embodiments, a resistance unit is configured to resist deployment of the needle until a critical force is applied by the user to the autoinjector, at which point, the resistance of the resistance unit is overcome. Continuous application of force by the user after the resistance is overcome drives the delivery device to the injection site where the medication is administered.