The present disclosure concerns an autoinjector needle-housing assembly extending along an axis in a longitudinal direction from a proximal end to a distal end, the autoinjector needle-housing assembly has a housing having a proximal part and a distal part attached to the proximal part, a needle attached to the proximal part of the housing, and a sterility barrier attached to the distal part of the housing, wherein the housing and the sterility barrier form a first sealed cavity, wherein a distal end of the needle is in the first sealed cavity, wherein the autoinjector needle-housing assembly has a recess formed by the distal end of the autoinjector needle-housing assembly, wherein the recess is shaped to receive a cartridge and to form a second sealed cavity between the autoinjector needle-housing assembly and said cartridge. Corresponding methods are also described.

An assembly for a cartridge needle insertion mechanism includes a housing, a cartridge needle defining a cartridge needle axis and a cartridge closed by a septum. A cartridge needle slider is linearly guided by the housing along an insertion axis to be moved by a driver from a first position, where the cartridge needle is not penetrating the septum, to a second position where the cartridge needle penetrates the septum of the cartridge. A cartridge needle holder holding the cartridge needle is operatively coupled with the cartridge needle slider to be moved with the cartridge needle slider from the first to the second position. The assembly includes a compliant coupling between the cartridge needle holder and the cartridge needle slider configured to facilitate movement of the cartridge needle holder with respect to the slider when moved into the second position, thereby compensating for needle penetration forces.

The invention relates to a safety assembly for preventing needle stick injury with a needle having a proximal end fixed to a tip of a medical container and a pointed distal end, the safety assembly having: an attachment ring fixed to the tip of the container and a safety device to cover at least the distal end of the needle, the safety device attached to the attachment ring. The safety assembly has an attachment ring having an inner ring and an outer ring to be snapped onto each other, the inner ring having an inner recess for applying glue between the inner ring and the tip, and the inner ring and outer ring having mutually engaging elements preventing any rotation of the outer ring relative to the inner ring.

The present disclosure relates to a administration assembly for a medicament delivery device, comprising: an elongated tubular delivery member cover (7), a cartridge holder (11) configured to be received by the delivery member cover (7) and configured to accommodate a medicament cartridge (31), the cartridge holder (11) having a radially flexible and radially inwards extending cartridge blocking protrusion (11b) configured to prevent the medicament cartridge (31) from moving proximally until being subjected to a proximally directed force larger than a threshold value, a needle assembly (13) comprising a double-edged needle having a proximally extending needle portion (13a) and a distally extending needle portion (13b), wherein the needle assembly (13) is configured to be assembled with the cartridge holder (11) so that the distally extending needle portion (13b) extends into the cartridge holder (11), and an administration mechanism including a plunger rod (27) configured to be proximally biased, wherein the delivery member cover (7) is configured to be linearly displaced in the distal direction relative to the cartridge holder (11), and wherein the delivery member cover (7) is configured to activate the administration mechanism when moved in the distal direction, causing the administration mechanism to move the cartridge holder (11) in the proximal direction and to subsequently move the plunger rod (27) in the proximal direction inside the cartridge holder (11) with a force larger than the threshold value.

A cartridge for dispensing a material, having: a sleeve having a longitudinal axis and a distal wall with a dispensing hole; a barrel defining a chamber for the material, including a proximal open end and a breakable distal wall at its distal end, and being movable in the sleeve between a first position where its distal wall is a distance from the sleeve's distal wall and a second position where its distal wall's sealing portion contacts an inner surface of the sleeve's distal wall; and a piston having a plate movable to seal the barrel's chamber. The sleeve includes an internal piercing element, near the dispensing hole, for breaking the barrel's distal wall upon moving the barrel from the first to the second position. Around the piercing element is an annular cavity delimited peripherally by a beveled inner surface that complements a beveled outer surface of the barrel.

The present invention relates to a drug injection cartridge and a drug injector comprising same, and has an anti-pushing part (100) formed between a needle part (10) and a cartridge (20), thereby preventing a rubber film from being expanded by pressure applied to the cartridge (20), such that a drug does not leak, and the accuracy of drug injection can be improved.

A syringe assembly includes a barrel defining a chamber therein, pressurized sterile air in the chamber, a plunger including a piston slidable in the chamber in a sealing relation to displace a fluid in the chamber, a seal configured to retain the pressurized sterile fluid in the chamber between the piston of the plunger and the seal when the plunger is stationary, and a needle assembly extending distally from the barrel and in fluid communication with the chamber of the barrel.

An example agent administration device may comprise a housing. The device may further comprise a sharp assembly including a delivery sharp. The sharp assembly may be reciprocally displaceable along a guide channel of the housing. The device may further comprise an access port in fluid communication with the delivery sharp. The device may further comprise an actuation assembly configured drive the sharp assembly, via urging of a single bias member, from a storage state in which the delivery sharp is within the housing, through a first extended position in which the delivery sharp extends a maximum distance from the housing and to a partially retracted position in which the delivery sharp extends a lesser distance from the housing.

An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.