The present disclosure relates to a medical delivery device that includes a barrel having an inner surface, a plunger rod having a distal end inserted within the barrel, and a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel. In at least one embodiment, the inner surface is hydrophilic. The stopper may include an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated with the one or more fluoropolymer layers. In some embodiments, the contact width between at least one rib having a sealing surface and the portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm.

A syringe transmits energy for injection satisfactorily to an injection objective substance while preventing influences of combustion products produced by the combustion of powder on the injection objective substance. A first piston part has a specific end face that receives ejection energy. A sealing member confines the combustion products in a first space separated by the sealing member. The sealing member has a fixed end portion and a contact portion that is in contact with the specific end face. In a state before the combustion of powder in an igniter, the contact portion is located at an initial position. With the combustion of powder in the igniter, the contact portion shifts to an ejection position with the sliding motion of the first piston part while being in contact with the specific end portion.

Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and assembling them into syringes, e.g., pre-filled syringes.

A thermoplastic elastomer stopper that meets the desired material properties of a stopper for a syringe assembly is disclosed. The compression set of the thermoplastic elastomer stopper of the present disclosure is 50% when measured at 25% compression for 22 hrs at 70 degree C. The hardness of the thermoplastic elastomer stopper of the present disclosure is 40-70 Shore A. The viscosity of a thermoplastic elastomer stopper of the present disclosure is 70 Pa.Math.s at 1,000 s.sup.1 shear rate, 12.0 Pa.Math.s at 10,000 s.sup.1 shear rate, and 3.0 Pa.Math.s at 50,000 s.sup.1 shear rate when measured using a capillary rheometer at 205 degree C. (Die: Roundhole 20 mm length/1 mm diameter/180 degree inlet, Piston: d=15 mm, and melting time=7 min). The present non-lubricated stopper exhibits the required functional performance of a lubricated stopper.

The present disclosure relates to a medical delivery device that includes a barrel having an inner surface, a plunger rod having a distal end inserted within the barrel, and a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel. In at least one embodiment, the inner surface is hydrophilic. The stopper may include an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated with the one or more fluoropolymer layers. In some embodiments, the contact width between at least one rib having a sealing surface and the portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm.

A drug injection syringe includes an injection needle assembly and a syringe body. The injection needle assembly includes an injection needle, a needle hub, an elastic body, and a fitting sleeve. The fitting sleeve accommodates the needle hub and the elastic body and has a fitting hole formed in a female taper shape. The syringe body includes an outer tube and a drug discharge tube formed in a male taper shape. The syringe body is attached to the injection needle assembly by pushing the drug discharge tube into the fitting hole by a press fitting. The elastic body couples the drug discharge tube and the injection needle in a liquid-tight manner by compressively deforming, due to the press fitting, at a protruding portion disposed on a periphery of the pocket and stretching against an inner wall of the fitting hole.

An injector allowing retraction/pulling of stem cells from adipose tissue via a suction tip and conservation of thereof in a tube without human touch or exposure to air, and it is characterized in that it has a movable modular piston allowing stem cells to be pulled into the tube via the suction tip, and a modular piston pin allowing the modular piston to stay in the tube and having a modular structure detachable from the modular piston.

A power injector (200) is disclosed that includes a number of features to address leakage of contrast media from a syringe that may occur while operating the power injector (200), for instance when loading fluid into a syringe after being installed on a powerhead (210) of the injector (200) and/or when purging air from such a syringe. One or more drainage channels (240) may be incorporated on a faceplate mounting (234) which in turn receives a faceplate (310), which in turn receives a syringe. A cover assembly (260) may utilize a form-in-place gasket (274) between its top cover (262) and its bottom cover (290). A bezel (330) includes an overlay (334) that is disposed over a touch screen display (380) that is aligned with a display aperture (264) through the top cover (262), and the bezel (330) may include a gasket (350) to seal against the top cover (262).

A syringe assembly and methods of producing the syringe assembly are described. The syringe assembly may include a syringe body, a plunger rod, a barrel cover, and a tamper evident device. The syringe body has a chamber configured to receive a material. The plunger rod moves within the chamber to dispense the material. The barrel cover covers the syringe body. The backstop is attached to the barrel cover to prevent a portion of the plunger rod from moving proximally through the backstop. The tamper evident device includes a tamper evident cap covering a distal portion of the syringe body, a collar attached to the barrel cover, and a frangible connection between the tamper evident cap and the collar.

Vented syringes are described herein. A vented syringe includes a syringe body and a plunger body. The syringe body defines a syringe cavity. The plunger body is at least partially disposed within the syringe cavity. The plunger body includes an air intake channel defined within the plunger body. The vented syringe further includes a plunger seal that is sealingly engaged with the syringe cavity to cooperatively define a syringe volume. The vented syringe further includes a one-way valve in fluid communication with the air intake channel and the syringe volume, wherein the one-way valve is configured to prevent fluid flow from the syringe volume to the air intake channel and permit fluid flow from the air intake channel to the syringe volume.