Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.

The present invention relates to a medicament delivery device comprising a housing, a biased medicament delivery member guard arranged movable in relation to the housing from a proximally extended position to a retracted position, a power pack comprising a plunger rod and a force element arranged to act on said plunger rod, which power pack is actuated by a release clip movable in relation to the housing and arranged to said plunger rod for releasably holding said plunger rod with the force element in a tensioned state; a rotator rotatably arranged inside said housing, which rotator is arranged with a guide element and a medicament delivery member guard lock element on its outer surface, wherein said medicament delivery member guard is arranged with release clip activation elements operably arranged to act on said release clip for releasing said plunger rod, and wherein said medicament delivery member guard is further arranged with a rotator activator element arranged to cooperate with said guide element for turning said rotator, upon movement of said medicament delivery member guard to the retracted position, and wherein, upon movement of said medicament delivery member guard back to the extended position, said rotator activator element will engage said medicament delivery member guard lock element and lock said medicament delivery member guard in a shielding position after removal of said medicament delivery device from a medicament delivery site.

The present invention relates to a disposable syringe for the prevention of reuse, and more specifically to a disposable syringe for the prevention of reuse, which can restrain a plunger from moving after a medicine has been exhausted using the pressure of the plunger, thereby fundamentally preventing the syringe from being reused.

It is known that fluids, for example, drugs, may be administered via a syringe. It is further known that in some instances, a second fluid must be administered following the administration of a first fluid in order to flush the first fluid. There are numerous reasons for why such flushing may be required and/or desirable. For example, flushing ensures that a patient has received the entirety of a dose of the first fluid (e.g., a drug), that the first fluid does not mix and/or react with a subsequently administered (third) fluid that may be incompatible with the first fluid, and/or that the infusion lines are clean and/or primed for a subsequent infusion, to cite a few examples. The present invention is a novel syringe design that houses the flushing solution as part of the syringe to streamline the fluid delivery (drug) and the flushing solution subsequently.

A piston for use in an injector comprising a cylinder having a longitudinal axis and an inner wall, which piston has a deformable sealing element with a convex surface, which deformable sealing element when the piston is inserted in the cylinder abuts the inner wall of the cylinder at an abutting interface and seals an annular gap between the piston and the inner wall of the cylinder. The abutting interface and the deformable sealing element have axial dimensions parallel with the longitudinal axis. The ratio between the axial dimension of the abutting interface and the axial dimension of the deformable sealing element is in the range between 0.01 and 0.2. In another aspect, an injector includes the piston and is used in a disposable syringe of the piston. The piston can prevent refilling of a syringe.

Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.

A reusable safety syringe training device is provided. The device comprises a syringe contained within a syringe protective member. The syringe protective member is movable vertically within an outer protective sheath from a first position to a second position and back to the first position. In the first position, the device is in an injection-ready position with the needle exposed and the syringe protective member in a locked vertical position with respect to the outer protective sheath. In the second position, the device is in a post-injection position such that the syringe protective member is no longer vertically locked with respect to the outer protective sheath and has moved vertically upward thereby rendering the needle within the outer protective sheath. The plunger carries a release flange sufficient to engage release latches that otherwise retain the syringe protective member in the first position. The release flange engages that release latches when the user pushes the plunger down to effectuate the injection. Once pressure is removed from the plunger after the injection has concluded, a springe mechanism drives the syringe protective member upwards to the second position. The user can then turn the plunger such that the release flange is no longer able to engage the release latches and push the plunger back down to lock the syringe protective member in its first position. The user is then able to pull the plunger back up while the syringe protective member remains locked, turn the plunger back to a position where the release flange is in a position to engage the release latches again, and perform another injection.

Embodiments of a retractable syringe assembly are provided that include a dual syringe barrel configuration. One or more embodiments include reuse prevention features and features that prevent premature activation of the retraction mechanism. Methods for aspirating and expelling liquid from medical devices are also provided.

The present invention relates to a drug delivery device comprising a drug container having at least one bellow. The at least one bellow has a first surface and an opposing second surface. The first surface is comprised of a first Belleville spring and the opposing second surface is comprised of a second Belleville spring, wherein the second Belleville spring has a higher spring rate than the first Belleville spring.

The present invention relates to a medicament delivery device comprising a housing (10, 20, 24, 30), a biased medicament delivery member guard (64) arranged movable in relation to the housing from a proximally extended position to a retracted position, a power pack (87) comprising a plunger rod (88) and a force element (118) arranged to act on said plunger rod (88), which power pack (87) is actuated by a release clip (96) movable in relation to the housing and arranged to said plunger rod (88) for releasibly holding said plunger rod (88) with the force element (118) in a tensioned state; a rotator (82) rotatably arranged inside said housing, which rotator (82) is arranged with a guide element (80) and a medicament delivery member guard lock element (84, 86) on its outer surface, wherein said medicament delivery member guard (64) is arranged with release clip activation elements (112) operably arranged to act on said release clip (96) for releasing said plunger rod, and wherein said medicament delivery member guard (64) is further arranged with a rotator activator element (78) arranged to cooperate with said guide element (80) for turning said rotator (82), upon movement of said medicament delivery member guard (64) to the retracted position, and wherein, upon movement of said medicament delivery member guard (64) back to the extended position, said rotator activator element (78) will engage said medicament delivery member guard lock element (84, 86) and lock said medicament delivery member guard (64) in a shielding position after removal of said medicament delivery device from a medicament delivery site.