The present invention provides a particulate delivery device with an automatic activation mechanism that pierces or cuts a composition capsule when a cap is removed. The cap cannot be replaced once the device is activated for use. The device allows for gas flow through the device from a gas inlet to a gas outlet through a composition receptacle and dispersion chamber to deliver particulate to the airway of a subject.

A dry powder inhaler with a blister folding device can include a housing to receive a single blister containing a dose of medicament for inhalation by a user, and a mouthpiece through which a dose of medicament is inhaled by a user and a blister opening device. The blister opening device can include a blister support element for supporting a blister containing a dose of medicament for inhalation by a user, and a blister folding element co-operable with the blister support element. The blister folding element and the blister support element can be movable relative to each other between a first position, for insertion of the blister into or onto the blister support element, and a second, burst, position in which the blister folding element has co-operated with the blister support element.

The present invention relates to an add-on device for a metered dose inhaler, an observance improvement system, and a method for improving observance of use in metered dose inhalers, the add-on device comprising an observance system housing component comprising an observance system with at least one pressure sensor; a mouthpiece component configured to fit, surround and removably engage with an exterior surface of a mouthpiece outlet provided on the metered dose inhaler; wherein said observance system housing is configured to fit and removably engage with said mouthpiece component; and said mouthpiece component is specifically adapted to conform to the exterior surface of the mouthpiece outlet of the metered dose inhaler without obstructing delivery of a dose of drug through said outlet.

Dispensing assembly, comprising a fluid product dispenser, such as a nasal dispenser, wherein the fluid product dispenser comprises a reservoir (10) provided with a bottom (11), a dispensing member (20), such as a pump or a valve, mounted on the reservoir (10), and a dispensing head (30) incorporating a dispensing orifice (31), the dispensing assembly comprising a lateral actuation device comprising a body (1) and a lateral actuation element (40) mounted so as to pivot on the body (1) about a pivot axis (45) between a rest position and an actuation position, the actuation element (40) comprising a bearing part (41), which is pressed by the user during actuation and a pushing part (42) designed to cooperate with the fluid product dispenser to effect the actuation thereof, the pivot axis (45) being arranged between the bearing part (41) and the pushing part (42), the lateral actuation member (40) having an S or inverted S shape, the bearing part (41) being arranged near the dispensing head (30) and the pushing part (42) being arranged under the bottom (11) of the reservoir (10).

An inhaler (10) for the inhalation of inhalable substances comprise: a canister (50) having an interior reservoir (84) containing pressurised inhalable substances including fluid; a metering valve (52) including a metering chamber (82) and a valve stem (54) defining a communication path between the metering chamber and the interior reservoir, the communication path (86) including an opening (106) configured to permit flow between a transfer space inside the valve stem and the interior reservoir, the interior reservoir being arranged for orientation above the metering chamber whereby gas such as air located within the metering chamber is replaced with liquid from the interior reservoir.

A dispenser for applying liquid, having a housing with an applicator opening and a liquid reservoir. The dispenser has a ventilation duct by which an ambient atmosphere is connected to the liquid reservoir so that, after the application of liquid, an inflow of air from the atmosphere is permitted into the liquid reservoir. The dispenser is provided with a detection installation which for detecting an application procedure detects air flowing in through the ventilation duct. The dispenser has a protective cap covering the applicator opening on the housing. The dispenser in the ventilation duct has a switch valve operable by activating a push-button on the external side of the housing. The protective cap acts on the push-button when placed on the housing or when the protective cap is being placed thereon to open the switch valve.

A dry powder inhaler including replaceable cartridges containing a dry powder for local or systemic delivery through the pulmonary tract and lungs is disclosed. The inhalers are used with inhalable dry powders, including medicament formulations comprising active agents for local or systemic delivery and for the treatment of diseases such as, pulmonary hypertension, cardiovascular disease, anaphylaxis, diabetes, obesity, cancer, and other diseases, or symptoms associated with these and other diseases, such as nausea, vomiting, pain and inflammation.

Provided is a blister pack for a dry powder inhaler, which dry powder inhaler is configured to deliver a first powder medicament and a second powder medicament different from the first powder medicament. The first and second powder medicaments are contained within blister pockets defined in a strip. A series of blister pockets is defined in the strip, which series extends linearly along the length of the strip. The first and second powder medicaments are contained in blister pockets, e.g. respective blister pockets, of the series. Alternatively or additionally, each of the blister pockets is elongated such as to have a largest dimension parallel with the length of the strip. These measures, either individually or in combination, enable minimizing of the width of the strip in spite of the strip accommodating both the first and second powder medicaments. This, in turn, may enable the depth/thickness of the dry powder inhaler to be minimized, and/or additional space to be provided inside the dry powder inhaler for accommodating, for example, use detection and wireless connectivity electronics for sending use detection data to an external device, such as a smartphone.

The spray application device with angled tip may comprise an applicator and an activator, where the applicator has a nozzle for delivery of a sprayable material. The spray application device may store a medication and may dispense the medication as an aerosol mist. The medication applicator may be adapted to dispense the medication through a nostril of a user directed at the posterior nasal cavity. The spray application device may be operable to release the medication in multiple doses of predetermined volume. The spray application device may be adapted for the user to self-administer the medication while positioned in any preferred physical position. A nozzle with a compliant nozzle shroud, an angled tip, and anatomically optimized nozzle geometry may direct the medication to a precise location within the posterior nasal cavity of a user.