An inhaler article includes a body extending along a longitudinal axis from a mouthpiece end to a distal end. A capsule cavity may be within the body bounded downstream by a mouthpiece. An air inlet at the distal end and an air outlet at the mouthpiece end. A first mouthpiece air channel may extend from the distal air inlet, through the capsule cavity to the mouthpiece air outlet. A second mouthpiece air channel may extend from a point downstream of the separator to the mouthpiece air outlet. The second mouthpiece air channel may be separate from the first mouthpiece air channel. A coating layer of flavour may be disposed on a surface of the second mouthpiece air channel and a protective layer may be disposed on the coating layer of flavour.

A nebulizer assembly and an airflow-guiding component thereof are provided. The airflow-guiding component includes an air-guiding part and a structural matching part. The air-guiding part includes a first hollow tube body, a second hollow tube body, and an air-guiding structure connected between the first hollow tube body and the second hollow tube body. The structural matching part is connected to the first hollow tube body. The air-guiding structure has a plurality of rear main air-introducing channels surrounding the first hollow tube body, and each of the plurality of rear main air-introducing channels has a rear main air-introducing opening perpendicular or inclined to the structural matching part. Therefore, external air outside the airflow-guiding component can be guided into the rear air-guiding channel through the plurality of rear main air-introducing channels.

An inhaler article includes a body extending along a longitudinal axis from a mouthpiece end to a distal end, a mouthpiece air outlet and a distal air inlet, and a capsule cavity within the body and bounded downstream by a mouthpiece. A separator is between the capsule cavity and the mouthpiece including at least one aperture to form an air flow path from the distal air inlet through the capsule cavity, through the mouthpiece to the mouthpiece air outlet. A coating layer of flavour is disposed on an interior surface of the mouthpiece and a protective layer disposed on the coating layer of flavour.

A device is provided for delivering a predetermined volume of at least one substance within a body cavity of a subject. The device contains a) a capsule for containing the predetermined volume of substances; b) a delivery end, having at least one orifice of diameter D, for placement in proximity to the body cavity; c) a valve mechanically connectable to the capsule, having at least two configurations: (i) an active configuration in which the valve enables delivery of the substances; and (ii) an inactive configuration, in which the valve prevents delivery of the substances from the capsule to the body cavity; and d) a fluid tight chamber configured to contain predetermined volume V.sub.gas of pressurized gas at a predetermined pressure, P.sub.gas. The capsule further contains at least one mixing mechanism that mixes the substances and the pressurized gas after the valve is reconfigured to the active configuration.

Provided herein are intranasal fluid delivery devices and apparatus comprising a dispensing tip a shot chamber carrying a fluid, the shot chamber having a diaphragm at one end and a plunger at the other end, and an actuator connected to a push rod moveable toward the shot chamber.

A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.

An indicating device includes a mechanical dose counter adapted to count the number of doses that have been dispensed from or remain in a container and an electronic module coupled to the mechanical dose counter and adapted to record when the doses have been dispensed from the container. Methods of using and assembling the device are also provided.

A syringe type ejection device capable of reducing an amount of residual liquid is provided. A syringe type ejection device includes: a barrel; a nozzle disposed to face the barrel; and a core inserted in the nozzle, the barrel having a large-diameter portion provided with a discharge space for discharging liquid, the nozzle being provided with a holding space for holding the core, the holding space being in communication with the discharge space, and the core being inserted in the discharge space.

A beneficial agent dispensing device comprises a dispenser body comprising a pressure chamber and at least one dispensing port. A flexible primary container stores the beneficial agent contained within the body. The arrangement is such that pressure in the pressure chamber depress the flexible primary container to expel the beneficial agent through the dispensing port. The beneficial agent dispenser can be configured to deliver the beneficial agent intranasally.

A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.