A personalized drug delivery apparatus comprising drug containing means; a spout configured to receive full lung exhalation; a mechanism configured to determine a personalized drug dosage according to the exhalation, the spout further configured to enable inhalation of the determined dosage.

There is provided a cartridge assembly for an aerosol-generating system, the cartridge assembly including a cartridge, a cartridge cover, and a mouthpiece. The cartridge includes at least one compartment having an air inlet and an air outlet. The cartridge cover is helicoidally moveable with respect to the cartridge between a first position in which the air inlet is obstructed and a second position in which air may flow through the air inlet. The mouthpiece is helicoidally moveable with respect to the cartridge between a third position in which the air outlet is obstructed and a fourth position in which air may flow through the air outlet.

A drug solution tank of the present invention is a drug solution tank for an ultrasonic inhaler, including a drug solution reservoir portion having an upper edge that surrounds an opening and a bottom portion formed so as to protrude downward, a flange portion formed so as to extend outward from the upper edge of the drug solution reservoir portion, and a leg portion that is continuous with the outer perimeter or lower surface of the flange portion, is formed so as to surround the drug solution reservoir portion, and extends downward past the bottom portion of the drug solution reservoir portion.

In a method and in an apparatus for the controlled delivery of particles, said particles are supplied to a measurement station in which the quantity of particles is detected. The particles are subsequently transferred by the measurement station to a dispensing device and are dispensed.

Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

A device according to one aspect of the present invention is an intranasal powdered medicine dispensing device (10) for dispensing a predetermined dose of a powdered medicine into a nasal cavity. The device includes a nozzle member (20) that includes a filling space (22) for a powdered medicine (M) and an ejection opening (26) for the powdered medicine (M), a closing member that closes the ejection opening (26), a sealing member (40) that seals an opening (24) of the filling space (22), an injection pump member (50) that sends out air, as the injection pump member contracts, to eject the powdered medicine from the ejection opening (26), a puncturing member (60) that moves, as the injection pump member (50) contracts, and forms a hole by puncturing in the sealing member (40) while moving, and a guide member (70) that restricts the puncturing member (60) from moving in a direction perpendicular to the direction of the movement thereof.

Provided is a blister pack for a dry powder inhaler, which dry powder inhaler is configured to deliver a first powder medicament and a second powder medicament different from the first powder medicament. The first and second powder medicaments are contained within blister pockets defined in a strip. A series of blister pockets is defined in the strip, which series extends linearly along the length of the strip. The first and second powder medicaments are contained in blister pockets, e.g. respective blister pockets, of the series. Alternatively or additionally, each of the blister pockets is elongated such as to have a largest dimension parallel with the length of the strip. These measures, either individually or in combination, enable minimizing of the width of the strip in spite of the strip accommodating both the first and second powder medicaments. This, in turn, may enable the depth/thickness of the dry powder inhaler to be minimized, and/or additional space to be provided inside the dry powder inhaler for accommodating, for example, use detection and wireless connectivity electronics for sending use detection data to an external device, such as a smartphone.

The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.

A cartridge for an aerosol-generating system is provided, including a liquid storage portion including a housing containing a liquid aerosol-forming substrate, the housing having an open end; and a heater assembly including: an electrical heating element configured to heat the substrate to form an aerosol, the heating element including a planar filament arrangement having one or more electrically conductive filaments, an electrically insulating substrate having a planar attachment face, the filament arrangement disposed on the planar attachment face, and connectors arranged at opposite ends of the heating element and forming two separate electrical contacts configured to apply power to the filament arrangement, at least a portion of the heater assembly is fluid-permeable, and the heater assembly is arranged over the open end of the housing.

There is provided a dose counter assembly for use with a medicament dispenser, the dose counter assembly comprising: a) a units dose display means comprising a first count indicia and one or more driver teeth; b) a tens dose display means comprising a second count indicia; and c) a driver, wherein the first count indicia and second count indicia align at a common viewing area to collectively display a count sequence.