Some embodiments of a device comprise a tubular flexible body that includes a channel though a longitudinal axis; a first sensor that is located in a distal end of the tubular flexible body; a second sensor that is located in the distal end of the tubular flexible body; and wiring that connects to the first sensor and the second sensor and that extends to a proximal end of the tubular flexible body, wherein a sensed orientation of the first sensor is oriented opposite to a sensed orientation of the second sensor.

A system for determining a location of a structure within a patients vasculature includes three or more pads adhered to the patients torso in a predetermined pad pattern. Each pad generates a pad electrical signal. A stylet has longitudinally spaced proximal and distal stylet ends, with at least one stylet electrode located proximate the distal stylet end. The stylet electrode receives the pad electrical signals and responsively generates a stylet electrical signal. A signal processor is operatively coupled for signal exchange with the stylet and to each of the pads via a selective electrical coupling. The signal processor compares the stylet electrical signal and at least two pad electrical signals to triangulate a position of the stylet electrode relative to each of the pads and responsively produce a triangulated position. The triangulated position is indicative of a position of the stylet electrode within the patients vasculature.

A medical device for insertion into a body may include a handle assembly including a handle body and a ball joint; a sensor assembly configured to electronically communicate with a magnet; a body extending longitudinally from the handle assembly; an articulation portion coupled to a distal end of the body, wherein the articulation portion includes a magnetic material; and an end effector coupled to a distal end of the articulation portion. The articulation portion may be configured to move upon application of a magnetic field from the magnet.

A system and method for integrating and synchronizing an automated mechanical cardiopulmonary resuscitation (CPR) device with components of cardiac catheterization laboratories so as to enhance the efficacy of each intervention. Synchronization can include image gating so that a monitor shows real time images during relaxation of the CPR, and a static image during compression of the CPR.

A method includes, in a processor, receiving signals from (i) a first position sensor disposed on a shaft of a catheter, and (ii) a second position sensor disposed on a distal end of a sheath of the catheter. Based on the signals received from the first position sensor and the second position sensor, an event is detected in which an expandable distal-end assembly of the catheter is being withdrawn into the sheath while still at least partially expanded. A responsive action is initiated in response to detecting the event.

The embodiments include an apparatus used in combination with a computer for sensing biopotentials. The apparatus includes a catheter in which there is a plurality of sensing electrodes, a corresponding plurality of local amplifiers, each coupled to one of the plurality of sensing electrodes, a data, control and power circuit coupled to the plurality of local amplifiers, and a photonic device bidirectionally communicating an electrical signal with the data, control and power circuit. An optical fiber optically communicated with the photonic device. The photonic device bidirectionally communicates an optical signal with the optical fiber. An optical interface device provides optical power to the optical fiber and thence to the photonic device and receives optical signals through the optical fiber from the photonic device. The optical interface device bidirectionally communicates an electrical data, control and power signal to the computer.

Disclosed herein are methods to restore myocardial conduction via the injection of conductive nanoparticles into the myocardium via an endovascular injection catheter.

There is provided a computerized method of tracking a position of an intra-body catheter, comprising: physically tracking coordinates of the position of a distal portion of a physical catheter within the physical body portion of the patient according to physically applied plurality of electrical fields within the body portion and measurements of the plurality of electrical fields performed by a plurality of physical electrodes at a distal portion of the physical catheter; registering the physically tracked coordinates with simulated coordinates generated according to a simulation of a simulated catheter within a simulation of the body of the patient, to identify differences between physically tracked location coordinates and the simulation coordinates; correcting the physically tracked location coordinates according to the registered simulation coordinates; and providing the corrected physically tracked location coordinates for presentation.

A system and method for delivering a medicament including a catheter configured for implantation in different target tissue sites, extending from a proximal end to a distal end, and having a sidewall which defines an internal lumen. The distal end has one or more apertures in the sidewall for the release of the medicament into the target tissue site; the system also comprises a medicament reservoir fluidly communicable with the internal lumen of each catheter, an adhesive member configured to adhere to the skin of the patient around the exit wound and having an opening therein to allow the catheters to pass through the adhesive member and a retaining member configured to be overlaid on the adhesive member and comprising a guide surface configured to receive a length of the two or more catheters and a plurality of retaining portions to retain the catheters against the guide surface.

A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108A) or a heart valve includes a light source (124), a first light guide (122A), a second light guide (122A), and an optical alignment system (257). The light source (124) generates light energy (224A, 224B, 324A, 324B, 424B). The first light guide (122A) receives the light energy (224A, 224B, 324A, 324B, 424B) from the light source (124). The first light guide (122A) has a guide proximal end (122P). The second light guide (122A) receives the light energy (224A, 224B, 324A, 324B, 424B) from the light source (124). The second light guide (122A) has a guide proximal end (122P). A multiplexer (223) directs the light energy (224A, 224B, 324A, 324B, 424B) toward the guide proximal end (122P) of the first light guide (122A) and the guide proximal end (122P) of the second light guide (122A). The optical alignment system (257) determines an alignment of the light energy (224A, 224B, 324A, 324B, 424B) relative to at least one of the guide proximal ends (122P). The optical alignment system (257) adjusts the positioning of the light energy (224A, 224B, 324A, 324B, 424B) relative to the at least one of the guide proximal ends (122P) based at least partially on the alignment of the light energy (224A, 224B, 324A, 324B, 424B) relative to the at least one of the guide proximal ends (122P).