An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

In some embodiments, an electronic laryngoscope includes a camera, a hollow connecting rod, a handle, and a control display. The front end of the connecting rod is connected to the camera, the rear end of the connecting rod is connected to the handle, and the rear end of the handle is connected to the control display. The laryngoscope further includes a hollow tube whose inner diameter is greater than the outer diameter of the connecting rod. The camera and the connecting rod are located on the inner side of the hollow tube. A sputum suction opening is formed between the front end of the hollow tube and the front end of the camera, and a sputum passage in communication with the opening is formed between the hollow tube and the connecting rod. The laryngoscope further includes a connector between the hollow tube and the camera and/or the connecting rod.

Double-lumen infusion catheter including: a shaft having proximal section, distal section, and intermediate section therebetween; first and second lumens extending along a length of the shaft and having arc shaped wall therebetween; and an inflatable member provided distally to intermediate section, and over the distal section. First lumen has cross section larger than cross section of second lumen and is configured to receive a guidewire therethrough and allow fluid flow via an unobstructed portion of first lumen. Unobstructed portion is formed along guidewire outer surface, between guidewire outer surface and inner wall of first lumen, and extends from an inlet at proximal end of intermediate section to an outlet at distal end of intermediate section. First lumen is narrowed to approximate a first diameter in shaft proximal and distal sections, and is widened to approximate a second diameter greater than first diameter in the shaft intermediate section.

Refreshing stylets, catheter systems, and methods thereof are disclosed. The refreshing stylet can be configured to fit within a lumen of a catheter such as hemodialysis catheter. The refreshing stylet can include an elongated hollow body having a proximal portion coupled to a needleless connector, a distal portion ending in a distal tip, an interior surface, an exterior surface, and a side hole. The exterior surface can be coated with a sustained-release formulation including one or more anti-thrombotic agents. The sustained-release formulation can be configured to contact a luminal surface of the catheter and prevent thrombus formation thereon. The side hole can be configured to provide a locking solution to the lumen of the catheter for locking the catheter between uses.

Drug delivery devices and systems, are provided for delivery of a drug into the upper urinary tract of patients in need thereof. The drug delivery devices (100) may be deployed directly into the renal pelvis via a patient's ureter, bladder, and urethra, and the drug delivery devices can be wholly retained therein for local continuous, controlled release of a drug over an extended period.

Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh. a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising an expandable mesh is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the mesh is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

An anchor strain relief member provides resistance to disengagement from a hemostatic valve due to forces tending to force the catheter in a proximal direction. The anchoring strain relief member is distal to a hub, joined to the catheter outer surface, and comprises a sealing portion that has at least one ridge that has a ridge tip and a ridge height defined by a distance from the ridge tip to the catheter central axis. Methods of forming a nested catheter system are described using a catheter with an anchor strain relief as the inner catheter for the nested catheter set. Systems of a hemostatic valve and a suitable catheter with an anchor strain relief member can provide for desired assemblies of components.

An integrated guidewire includes a wire and a flexible tube. The wire is sized and shaped to move in an anatomical material transportation system of a patient. The flexible tube is sized and shaped to move in the anatomical material transportation system, having proximal and distal ends, the proximal-end is coupled to a device external to the patient, the flexible tube is configured to transfer fluids between the distal-end and the device, and the wire and the flexible tube are intertwined with respect to one another.

Devices, assemblies, systems, and techniques described herein may facilitate the delivery of medical fluid, such as an adhesive, to a patient. For example, a medical assembly may include a flexible catheter configured to be disposed within an anatomical structure of a patient, wherein the flexible catheter defines a lumen configured to contain a volume of medical adhesive. The medical assembly may also include a shaft defining a shaft cross-sectional dimension smaller than a lumen cross-sectional dimension of the lumen, wherein advancement of the shaft through at least a portion of the lumen forces at least a portion of the volume of medical adhesive out of the distal opening of the lumen of the flexible catheter.

An occludable venous catheter device includes a needle tube with a needle tube base; a venous catheter with a venous catheter base; a sealer, a front portion disposed inside a venous catheter lumen, a front end exposed out of a front-end opening; an occluding wire; an isolating element; a guide passage with a straight tube portion; a front-end opening connected to the venous catheter lumen; wherein the occluding wire is capable of entering the venous catheter lumen; the straight tube portion is coaxial with the venous catheter or is capable of moving in an externally-isolated manner to a position such that a central axis of the straight tube portion coincides with a central axis of the venous catheter; the occluding wire and the guide passage reach directly inside a chamber and are isolated from the outer environment.