Systems and methods for implanting a lead. The system includes an active guidewire having proximal and distal ends. The distal end includes a guidewire anchor that is configured to be attached to a target SOL. The active guidewire is configured to be utilized to electrically map the target SOI by at least one of delivering stimulation energy through the active guide wire to the target SOI or sensing an evoked response at the target SOI from the guidewire. The system also includes a lead having a lead body with proximal and distal ends and with a lumen extending between the proximal and distal ends. The distal end of the lead body is configured to receive the proximal end of the active guidewire. The lumen is configured to permit the lead body to be advanced over the active guidewire.

Disclosed are access systems, devices, and methods for internal access to a patient's body. For example, an access device for placing an acute dialysis catheter can include a frame; a housing, a pair of guidewire clamps, and a needle disposed on the frame; a dilator coupled to the frame, and an access guidewire in a ready-to-deploy state of the access device. The pair of guidewire clamps can be disposed on the frame between an end portion of the frame and a distal end of the housing for clamping the access guidewire. A needle hub of the needle can be disposed on the frame between the pair of guidewire clamps. The dilator can distally extend from the end portion of frame. A needle shaft of the needle can distally extend beyond a distal end of the dilator allowing the needle to establish an insertion site for the acute dialysis catheter.

The present invention relates to methods of transvascular retrograde access placement and to devices that facilitate these methods. For purposes of the present invention, transvascular retrograde access placement generally comprises the insertion of a vascular catheter into a central blood vessel through the puncturing of the central blood vessel from the inside of the central blood vessel with a needle or other similarly configured device, or a needle-tipped guidewire of the present invention, and exiting that needle from the patient through the skin rather than the traditional approach of inserting a needle from the outside of the skin surface to the inside of a blood vessel.

A medical clip for holding a medical device. The medical clip includes a first jaw and a second jaw rotatably coupled to the first jaw, the first jaw and the second jaw being rotatable with respect to each other between a closed position and an open position; an elastomeric insert configured to be positioned between the first jaw and the second jaw. The elastomeric insert defining a cavity having a cavity depth that receives a medical device between the first jaw and the second jaw. In the closed position, a distal face of the first jaw and the second jaw define a distal opening configured to receive a portion of the medical device through the distal opening; and, a proximal face of the first jaw and the second jaw define a proximal opening configured to receive a second portion of the medical device through the proximal opening.

An intraluminal guide wire may include an elongated shaft extending between a distal and a proximal end. The guide wire may include a user actuation segment positioned proximal to the proximal end of the shaft and configured for movement relative to the shaft. The guide wire may include a core wire affixed to the user actuation segment and the distal end of the shaft. The guide wire may also include an inner member having a proximal end situated at least partially within and fixed relative to the user actuation segment and a distal end situated partially within the shaft, the core wire passing through the inner member. The guide wire may be configured with a distal segment of the inner member within the shaft exhibiting a friction-based restraint on movement within the shaft. The friction-based restraint on movement may be a frictional force between the inner member and the shaft.

Torque devices for navigating a guidewire through a body lumen are disclosed. The devices have a variable speed transmission design, including at least a first transmission region along a first position of the device, and a second transmission region along a second position of the device. The first and second transmission regions have different diameters, thereby allowing rotational control of the guidewire between at least two different stroke angles.

Intravascular delivery system for deployment of a therapeutic device, such as a stent, in a controlled and robust manner is supported by a lockable balloon catheter equipped with a locking mechanism configured to lock in vivo to a delivery component, such as a guidewire. The lockable balloon catheter can be controllably transitioned between a locked and an unlocked modes of operation by inflation/deflation of the balloon of the lockable balloon catheter. Being in the locked mode of operation, the lockable balloon catheter facilitates delivery of the therapeutic element along the delivery component to a target site while enhancing the stability of the delivery component, especially near the target site.

A guide wire introduction device for positioning at least one guide wire around a heart valve. The device includes a first catheter provided with a distal deflection system, a second catheter inserted inside the first catheter, at least one lumen capable of causing a guide wire to slide therein and provided with a distal deflection system for deflecting the end thereof through an angle greater than 90°, and a third catheter inserted inside the first catheter. The third catheter has a guide wire capturing device therein and is provided with a distal deflection system.

A medical device may comprise a shaft, an articulation wire extending through at least a portion of the shaft, and a handle, including a handle body having an outer surface that defines a channel. A distal portion of the shaft may be received within a first portion of the channel. A distal portion of the articulation wire may be received within a second portion of the channel. A control member may be movable relative to the handle body to move the distal portion of the articulation wire relative to the distal portion of the shaft.

Described are methods, systems, devices for facilitation of intraluminal medical procedures within the neurovasculature. A catheter advancement device includes a flexible elongate body having a proximal end, a distal end, and a single lumen extending therebetween. The flexible elongate body has a proximal segment, an intermediate segment, and a tip segment. The proximal segment includes a hypotube coated with a polymer. The intermediate segment includes an unreinforced polymer having a durometer of no more than 72D. The tip segment is formed of a polymer different from the intermediate segment and has a durometer of no more than about 35D and a length of at least 5 cm. The tip segment has a tapered portion that tapers distally from a first outer diameter to a second outer diameter over a length of between 1 and 3