Guidewires are disclosed being configured to achieve variable rigidity to facilitate percutaneous exploration and the traversal of overlying elements such as catheters, for instance in performing the Seldinger technique. Embodiments of guidewires comprise sheaths and cores configured to be tightened together to achieve stiffness of the guidewire. Embodiments further include cores having an axial passage, along with one or more sections capable of independent activation to achieve variable rigidity. Embodiments also include guidewires comprising combinations of solid, wound metallic, or polymeric coils, or woven meshes, with attached or detached polymer coatings. Cores may be configured to increase or decrease pressure, pass acoustic, ultrasonic or other mechanical energy, pass one or more metallic cores to interact with the distal mechanical elements, or as a channel to pass wires to activate the distal materials in the sections and distal tip.

A shape sensing enabled instrument includes a flexible longitudinal body (103) including an outer surface which encapsulates interior features. The interior features include an optical fiber lumen (105) configured to receive one or more optical fibers for optical shape sensing, and a mechanical member (107) forming a hollow extending longitudinally down the body. The mechanical member is configured to receive the optical fiber lumen therein to permit rotation and translation of an optical fiber and to protect the optical fiber.

A percutaneous guidewire comprising a distal end portion that is pre-formed in a curve that turns through more than 270 degrees. The stiffness of the guidewire may decrease continuously along the length of the curved distal end portion towards the tip of the guidewire and the radius of curvature of the curved distal end portion may also decrease towards the tip of the guidewire.

A dilator assembly comprising an elongated body having a proximal end and a distal end, a first lumen extending along the body, a second lumen extending along the body so that it is a parallel to the first lumen, and a joint lumen disposed adjacent the distal end of the body, wherein both the first lumen and second lumen are in fluid communication with the joint lumen. A guidewire has a first end and a second end, and the first end of the guidewire is slidably received in the first lumen and the second end of the guidewire is slidably received in the second lumen.

A medical guidewire includes a flexible spiral coil, a fiber, and a strengthening element. The coil is configured to guide a medical device into a patient body. The fiber extends along at least part of the coil, is coupled to the at least part of the coil at one or more first predefined locations and is configured to mechanically strengthen the at least part of the coil. The strengthening element is coupled to one or more second predefined locations along a distal section of the coil, and is configured to mechanically strengthen the distal section.

An integrated guidewire includes a wire and an optical fiber. The wire is sized and shaped to move in an anatomical material transportation system of a patient. The optical fiber has proximal and distal ends, the proximal-end is coupled to a device external to the patient, the optical fiber is configured to transfer optical signals between the distal-end and the device, and the wire and the optical fiber are intertwined with respect to one another.

In a medical guide wire having a connecting structure formed by three members: a tubular connector; a first core; and a second core, when a torsional rigidity of one member is lower than the torsional rigidity of the materials of both end portions, for example, the twist is unevenly generated between the members and the rotation transmission performance to the distal end side is significantly reduced. In such a case, there is a technical problem for improving the rotation transmission performance to the distal end side. In the connecting structure formed by three members, as a result of focusing on the torsional rigidity of the three members and considering the torsional rigidity ratios between the members, the technical problem for improving the rotation transmission performance to the distal end side can be solved when the torsional rigidity ratios satisfy a predetermined relation.

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. The array is selectively transformable between a delivery or low-profile state (e.g., a generally straight shape) and a deployed state (e.g., a radially expanded, generally spiral/helical shape). The multi-electrode array is sized and shaped so that the electrodes or energy delivery elements contact an interior wall of the renal blood vessel when the array is in the deployed (e.g., spiral/helical) state. The electrodes or energy delivery elements are configured for direct and/or indirect application of thermal and/or electrical energy to heat or otherwise electrically modulate neural fibers that contribute to renal function.

A device including a catheter (14) and a medical instrument (12). The catheter includes an inner portion (16) and one or more unlocking features (18). The medical instrument includes one or more locking features (24). When the medical instrument is in the inner portion of the catheter, the one or more unlocking features engage the one or more locking features so that the medical instrument can bend in the catheter. When the medical instrument is outside the catheter, the one or more unlocking features disengage from the one or more locking features so that the medical instrument is restricted from bending.

A guidewire torquer comprising a handling body for handling of the guidewire torquer and guidewire holding surfaces oriented for engaging the guidewire from mutually opposite sides of the guidewire and holding the guidewire in an elastically tensioned, bent guidewire shape providing frictional fixation of the guidewire relative to the handling body. The guidewire holding surfaces project from an abutment plane defined by at least one abutment surface. A guidewire trajectory of the bent guidewire shape extends along and touches the guidewire holding surfaces is accessible from a direction in which the at least one abutment surface is facing. At least portions of the guidewire holding surfaces lean over towards or face the abutment plane for holding the guidewire adjacent to said abutment plane, and the guidewire holding surfaces are part of a single, rigid body portion.