The present disclosure relates to interventional devices such as catheters and guidewire devices having micro-fabricated features for providing flexibility while maintaining good torquability. An interventional device includes an elongated member (500) having an arrangement of fenestrations which define a plurality of axially extending beams coupling a plurality of circumferentially extending rings. The fenestrations are arranged so that the resulting beams form a distributed, non-helical and non-linear pattern along the length of the elongated member. The pattern of fenestrations thereby minimizes or eliminates preferred bending axes.

A section is disclosed for use with a portion assembly. The section can include a solid core section with a distal section having a first diameter, and a proximal section having a second diameter, wherein the second diameter can be greater than the first diameter. The section can include a coil wound around the distal section of the solid core section. The proximal section can have a flexural stiffness that is less than a flexural stiffness of the distal section. A length of the distal section of the section may be shorter than the length of the portion. A length of the proximal section of the section may be longer than the length of the portion.

An integrated guidewire includes a wire and a flexible tube. The wire is sized and shaped to move in an anatomical material transportation system of a patient. The flexible tube is sized and shaped to move in the anatomical material transportation system, having proximal and distal ends, the proximal-end is coupled to a device external to the patient, the flexible tube is configured to transfer fluids between the distal-end and the device, and the wire and the flexible tube are intertwined with respect to one another.

Infusion devices including a cannula have a tubular body member comprising a tubular wall enclosing a longitudinal extending internal bore. The cannula is adapted to flex in response to a compression force and/or an increased internal pressure in the cannula.

A pressure guidewire is provided that has a proximal end and a distal end. The pressure guidewire has a proximal section a sensor housing section, and an intermediate section. The proximal section extends from the proximal end of the pressure guidewire to a distal end of the proximal section. The sensor housing section is disposed adjacent to the distal end of the pressure guidewire. The intermediate section disposed between the proximal section and the sensor housing section. The intermediate section has a proximal end separate from the proximal section. The proximal end can be coupled to the distal end of the proximal section. The pressure guidewire has a tubular body positioned within the intermediate section. A pressure sensor is positioned in the sensor housing section

Disclosed is a minimally invasive miniaturized percutaneous mechanical circulatory support system. The system may be placed across the aortic valve via a single femoral arterial access point. The system includes a low profile axial rotary blood pump carried by the distal end of a catheter. The system can be percutaneously inserted through the femoral artery and positioned across the aortic valve into the left ventricle. The device actively unloads the left ventricle by pumping blood from the left ventricle into the ascending aorta and systemic circulation. A magnetic drive and encased motor housing allows for purgeless operation for extended periods of time to treat various ailments, for example more than six hours as acute therapy for cardiogenic shock.

Disclosed is a mechanical circulatory support system for transcatheter delivery to the heart, having a removable guidewire aid to assist with inserting the guidewire along a path that avoids a rotating impeller. The system may comprise a catheter shaft and a circulatory support device carried by the shaft. The device may comprise a tubular housing, an impeller and the guidewire aid. The guidewire aid may include a removable guidewire guide tube. The guide tube may enter a first guidewire port of the tubular housing, exit the tubular housing via a second guidewire port on a side wall of the tubular housing on a distal side of the impeller, enter a third guidewire port on a proximal side of the impeller, and extend proximally through the catheter shaft.

A guide wire that has an atraumatic and flexible loop that expands within a vessel, with indicators that indicate the degree of expansion. The indicators are used to determine the degree of expansion through the use of radio-opaque markers, hydraulic, and electrical signals. The guide wire enables safe passage into target vessels while providing user feedback on inadvertent passage into side branches and diseased segments.

A guide wire having a conductive portion coated with an insulating film without impairing mobility of a diaphragm. The diaphragm and the conductive portion are on a surface perpendicularly intersecting with an axial line direction. A guide wire main body has a housing having an internal space with a pressure sensor therein. The pressure sensor includes a sensor main body having a distal end surface perpendicularly intersecting with an axial direction of the guide wire main body and facing a distal end, a diaphragm located on the distal end surface, resistive bodies each having a variable electrical resistance value by being deformed together with the diaphragm, terminals connected to the resistive bodies, conductive wires attached to the terminals with solder. Insulating films is formed by electrodeposition coating on a portion of the terminals, solder, and conductive wires.

A guidewire kit including a guidewire with a shaft having a curved steering section and including a straightener bounding a lumen for straightening at least the curved deflection section of the guidewire extending into the lumen for insertion of the tip and the curved deflection section of the guidewire into a needle inserted into a vessel of a patient. The straightener is of a length of at least 8 cm for obtaining an improved and more reliable steering effect of the curved steering section.