A guide wire includes a core shaft, a coil body disposed around an outer periphery of the core shaft, and a joining portion joining a distal end of the core shaft to a distal end of the coil body 3, An outer periphery of the joining portion has, at its proximal end, an uneven shape in a longitudinal direction of the guide wire. The outer periphery may include a protruded portion that protrudes proximally in the longitudinal direction, and a recessed portion that protrudes distally in the longitudinal direction. The guide wire has improved joining strength between the joining portion and the coil body, preventing the joining portion from detaching from the coil body.

A guide wire is disclosed for guiding a tubular elongated body to be inserted into a living body can include: an elongated shaft portion that has flexibility; a puncture portion that is disposed at a distal end portion of the shaft portion and forms a hole in a biological tissue; and a cover portion that is formed of a wire member wound in a spiral shape, has a contraction portion that is contractible, and covers the puncture portion. The contraction portion is capable of causing the puncture portion to protrude from the cover portion by contracting the contraction portion in a linear state. When the contraction portion is in a curved state, the contraction portion is restricted in contraction so that the puncture portion does not protrude from the cover portion by contact of adjacent wire members on a concave side.

An integrated guidewire includes a wire and a flexible tube. The wire is sized and shaped to move in an anatomical material transportation system of a patient. The flexible tube is sized and shaped to move in the anatomical material transportation system, having proximal and distal ends, the proximal-end is coupled to a device external to the patient, the flexible tube is configured to transfer fluids between the distal-end and the device, and the wire and the flexible tube are intertwined with respect to one another.

A guide wire includes a core shaft, and a coil body wound around a distal end side of the core shaft, and a distal tip to which a distal end portion of the core shaft and a distal end portion of the coil body are fixed. The distal end portion of the core shaft has a rectangular transverse sectional shape, and an aspect ratio of the rectangle is greater than or equal to 1:1 and less than or equal to 1.08:1.

The invention provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes an elongate shaft having a distal region and a coil disposed along the distal region. The coil is formed from a winding member having a first filar region and a second filar region. The winding member has a first cross-sectional diameter along the first filar region, a second cross-sectional diameter different from the first cross-sectional diameter along the second filar region, a first centroid at a first position along the first filar region and a second centroid at a second position along the second filar region. The first centroid and the second centroid are axially-aligned.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes providing an intravascular device having a distal portion with a lumen extending therein; inserting the device into the vascular lumen; positioning the distal portion in the vascular wall; and directing the distal portion within the vascular wall.

Intraluminal and endovascular devices and methods of manufacturing intraluminal and endovascular devices may be provided. In one implementation, an intraluminal device may include a sheath having a flexible distal bending segment and a core wire arranged within the sheath. The core wire may include a distal end portion doubled back in a loop within the sheath such that the distal tip of the core wire is situated proximally from the loop. The intraluminal device may also include a movement restrictor within the sheath that is configured to limit axial movement of the distal tip of the core wire. Limiting the axial movement of the core wire distal tip may cause the loop of the core wire to buckle, resulting in a bend in the distal bending segment of the sheath, when a force is exerted on the core wire.

A guide wire includes a core shaft and a twisted wire coil body having a plurality of wires twisted together and arranged along an outer periphery of the core shaft. The twisted wire coil body includes a distal end portion including a distal end and a feature portion, and a proximal end portion, and has a smaller outer diameter in the feature portion than at the proximal end portion. Among the plurality of wires, an outermost wire having a longest distance to a center point of the core shaft in a transverse cross section of the twisted wire coil body in the feature portion, has a smaller cross-sectional area than a wire having a longest distance to the center point in a transverse cross section of the twisted wire coil body at the proximal end portion. An inner diameter of the twisted wire coil body is constant.

A medical guide wire with excellent visibility is provided. A medical guide wire including: a wire body (2) that is flexible and long; a covering layer (3) covering a surface of the wire body (2); and a wire material (4) helically arranged on the covering layer (3), wherein the covering layer (3) is formed of a transparent material same as a transparent material of the wire material (4), and the wire material (4) is arranged at a regular pitch along the longitudinal direction of the wire body (2).

A method for measuring a distance in a body vessel and introducing an implant into the body vessel, the method comprising: providing a guide wire, wherein the guide wire comprises a proximal end and a distal end, wherein the distal end comprises a spiral which has at least two adjoining spiral sections as markings, wherein at least a surface of one spiral section comprises a first material and at least a surface of the second spiral section comprises a second material, and further wherein the first material is different than the second material; inserting the guide wire into the body vessel; measuring the distance in the body vessel using the markings on the guide wire; and delivering the implant over the guide wire to the body vessel.