A guide wire including a first core shaft, a second core shaft, a covering member, and a joint layer. The first core shaft has a first large-diameter portion and a first small-diameter portion, and the second core shaft has a second large-diameter portion and a second small-diameter portion. The covering member covers a contact portion where the first and second small-diameter portions are arranged opposite to each other, and at least a part of each of the first and second small-diameter portions are adjacent to the contact portion. The joint layer joins the covering member with the first and second small-diameter portions inside the member. A length of the covering member is shorter than a sum of the lengths of the first and the second small-diameter portion in the axial direction, and longer than the shorter of the lengths of the first and second small-diameter portions in the axial direction.

A guidewire for use in intravascular procedures has a solder or weld joint at a distal end thereof. A plurality of dimples are formed on the solder/weld joint to increase the engagement and penetration of fibrous material including chronic total occlusions (CTO).

Intraluminal and endovascular devices and methods of manufacturing intraluminal and endovascular devices may be provided. In one implementation, an intraluminal device may include a sheath having a flexible distal bending segment and a core wire arranged within the sheath. The core wire may include a distal end portion doubled back in a loop within the sheath such that the distal tip of the core wire is situated proximally from the loop. The intraluminal device may also include a movement restrictor within the sheath that is configured to limit axial movement of the distal tip of the core wire. Limiting the axial movement of the core wire distal tip may cause the loop of the core wire to buckle, resulting in a bend in the distal bending segment of the sheath, when a force is exerted on the core wire.

A delivery system is disclosed which can be used to deliver an ocular implant into a target location within the eye via an ab interno procedure. In some embodiments, the implant can provide fluid communication between the anterior chamber and the suprachoroidal or supraciliary space while in an implanted state. The delivery system can include a proximal handle component and a distal delivery component. In addition, the proximal handle component can include an actuator to control the release of the implant from the delivery component into the target location in the eye.

The present disclosure describes delivery cables for delivering a medical device. In one embodiment, a delivery cable includes a flexible inner core, a proximal outer coil, and a distal outer coil. The proximal outer coil has a first rigidity. The distal outer coil surrounds at least a portion of a distal section of the flexible inner core and has a second rigidity less than the first rigidity thereby, thereby reducing bias placed on the medical device by the delivery cable.

Provided is a pressure guide wire, including a proximal portion (1), an intermediate portion (2) and a distal portion (12), the intermediate portion (2) is composed of one or more woven layers, wherein each woven layer includes a plurality of woven wires, the distal portion (12) includes a sensor housing (4) that holds a pressure sensor (5) and a head end assembly (11), the head end assembly (11) includes a developing spring (9) and a head end core wire (11) nested within the developing spring (9). The pressure guide wire having such a structure has good flexibility and supportability, meanwhile, the cost of the pressure guide wire can be reduced due to the low cost of the woven wire and the weaving process.

A tubular body that includes a plurality of first wires distributed in an annular portion of the tubular body, and a plurality of deformed second wires alternately disposed between each of the plurality of first wires, the plurality of first wires and the plurality of deformed second wires being in an alternately twisted arrangement in a longitudinal direction of the tubular body, where each of the plurality of first wires has a substantially circular shape in a cross section view, and each of the plurality of deformed second wires has a non-circular shape in the cross section view, has an arcuate side portion that receive a part of a side surface of an adjacent wire of the plurality of first wires, and has an annular sector shape protruding in a radial direction in the cross section view of the tubular body.

The present disclosure relates to vascular devices such as guidewires and microcatheters having integrated coil sections for optimizing torquability, flexibility, and ability to shape and maintain the distal tip. A guidewire device includes a core and a tube structure coupled to the core such that at least a portion of the core passes into the tube structure. A distal section of the tube structure includes a spiral cut arrangement that configures the distal section as an integral coil integrally incorporated as part of the tube structure. The integrated coil configuration increases the flexibility of the tube structure to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device.

Devices and systems for obtaining conductance data and methods of manufacturing and using the same. In at least one embodiment of a device of the present disclosure, the device is an elongated body with at least one groove defined therein, the at least one groove configured to receive one or more conductor wires therein. In another embodiment, the device is an elongated core body having a plurality of conductive elements positioned thereon and a coating to result in a device having an overall round-cross section.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes providing an intravascular device having a distal portion with a lumen extending therein; inserting the device into the vascular lumen; positioning the distal portion in the vascular wall; and directing the distal portion within the vascular wall.