Apparatus, including a probe having a distal end insertable into a nasal sinus of a human patient, and a location sensor positioned within the distal end. A sinuplasty balloon is positioned on the distal end at a selected opening of the nasal sinus. A processor receives first signals from the location sensor while the distal end is inserted into the nasal sinus and prior to positioning of the balloon at the selected opening, and generates a first map of the sinus. The processor inflates the balloon when it is at the selected opening, so as to enlarge the selected opening, and subsequently deflates the balloon. The processor then receives second signals from the location sensor and generates therefrom a second map of the sinus. The processor registers the first map with the second map and generates from the registered maps a numerical increase in size of the selected opening.

Devices, systems, and methods for inflation are provided. Inflation devices include a housing, a compressed gas canister disposed therein, a syringe disposed within the housing, a plunger slidably disposed in the syringe having an unloaded position and a loaded position relative to the syringe., a puncture mechanism disposed within the housing and configured to open a fluid path between the compressed gas canister and the syringe, and a positive pressure mechanism disposed within the housing and operably coupled to the syringe. Engagement of the puncture mechanism puts the syringe into fluid communication with the compressed gas canister such that gas contained therein loads into the syringe and the plunger moves from the unloaded position and the loaded position. The positive pressure mechanism is configured to maintain the gas within the syringe at a positive pressure relative to ambient pressure in order to prevent air from entering the syringe after loading.

Several embodiments of a catheter are described, having a balloon configured to slowly inflate and then quickly deflate to create an area of low pressure in the vessels. The balloon can be cycled near the vessels of the kidneys, thereby helping to draw out blood from the kidneys and enhance fluid processing to the bladder.

A balloon catheter including an elongated catheter main body portion and a balloon provided on the distal portion of the catheter main body portion. The balloon is inflatable to expand radially outward into an inflated state and deflatable to contract radially inward into a deflated state. The catheter main body portion includes a hollow outer tube and a hollow inner tube disposed within the outer tube. The balloon includes a contact portion that contacts the outer surface of the inner tube and a vane portion protruding from the contact portion radially outward when the balloon is in the deflated state. The contact portion of the balloon includes a connecting portion that connects the balloon to the catheter main body portion.

Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.

An apparatus for vascular denervation, comprising a catheter configured for delivery into a vessel of a patient. A balloon is mounted on a distal tip of the catheter, the balloon being configured to be inflatable and further configured so that, upon inflation, the balloon adopts a shape that includes a first edge and a second edge that wind around each other in a double helix, the first edge and the second edge being separated from each other by a first crease and a second crease that also wind around each other in a double helix. A first electrode is attached to the balloon and is located to extend along the first edge.

An occlusion catheter system includes an inflation catheter member and an occlusion balloon. The proximal and distal balloon ends are connected to the inflation catheter between the proximal and distal catheter ends. A distal pressure sensor is attached to the inflation catheter member between the proximal balloon end and the atraumatic tip. An inflatable spine is connected to the inflation catheter. The proximal spine end is connected to the inflation catheter near the proximal balloon end and the distal spine end is connected to the inflation catheter near the distal balloon end. The occlusion balloon and the inflatable spine are configured to define blood flow channels with the internal surface and the external balloon surface when the occlusion catheter system is at least partially positioned in the vessel and the occlusion balloon and the inflatable spine are in a partially inflated configuration.

Provided is a pressure gauge capable of being effectively used for internal pressure measurement of a balloon catheter and capable of providing easy monitoring of a pressure value even when measuring internal pressure of an extracorporeal circulation circuit. The pressure gauge measures internal pressure of a balloon catheter used for treatment and diagnosis or pressure of a body lumen of a living body and includes a coil-shaped tube 2 to elastically deform. One end of the tube 2 is set as an open fixed end and the other end is set as a sealed free end and pressure introduced from the open fixed end can be measured based on a displacement position of the tube 2 due to the pressure.

Manifolds and methods of operating manifolds are provided. An example manifold for controlling multi-lumen devices is provided that includes a substance supply mechanism. The substance supply mechanism independently provides a substance to, or remove a substance from, each of a plurality of lumens. The example manifold also includes a lumen selection mechanism. The lumen selection mechanism selectively opens and closes a connection between the substance supply mechanism and at least one of the plurality of lumens. A corresponding method of operation is also provided. An example embodiment also includes a manifold for use with a vessel seclusion device.

A joint-spacing balloon catheter comprising: a shaft having a distal end and a proximal end; first and second balloons mounted to the distal end of the shaft, the first balloon being disposed distal to, and spaced from, the second balloon, with the portion of the shaft between the first and second balloons being flexible; and a handle attached to the proximal end of the shaft.