Manifolds and methods of operating manifolds are provided. An example manifold for controlling multi-lumen devices is provided that includes a substance supply mechanism. The substance supply mechanism independently provides a substance to, or remove a substance from, each of a plurality of lumens. The example manifold also includes a lumen selection mechanism. The lumen selection mechanism selectively opens and closes a connection between the substance supply mechanism and at least one of the plurality of lumens. A corresponding method of operation is also provided. An example embodiment also includes a manifold for use with a vessel seclusion device.

An endoscopy system including a balloon-equipped endoscope including a balloon which is configured for slidable frictional engagement with an interior wall of a body passageway and axial stretching of the interior wall when inflated to a slidable frictional engagement pressure and displaced axially along the body passageway and a balloon inflation subsystem operative to selectably inflate the balloon to the slidable frictional engagement pressure.

Provided is a balloon with multiple small segments (balloons) fused to each other along the shaft of the balloon. Each segment has a different pressure profile. Each segment has a separate outlet (slot) used for its inflation with the required pressure according to the tightness and calcification of the lesion of the arterial wall. Each segment can be inflated with different pressures and the apposition of the overlying stent can be confirmed without the need for another non compliant balloon which carry many complications and add extra cost.

A treatment method includes: inserting a first closure and a second closure into a tubular organ, wherein the tubular organ includes at least one affected site; contacting an inner wall of the tubular organ with the first closure and the second closure to close the tubular organ with the at least one affected site located between the first closure and the second closure; with the tubular organ closed by the first closure and the second closure, aspirating a gas located in the tubular organ between the first closure and the second closure; and with the tubular organ closed by the first closure and the second closure, delivering a liquid medicine into the tubular organ between the first closure and the second closure.

A balloon catheter which allows for faster preparation and effective purging of air. The catheter includes an elongated, flexible catheter having a tubular outer member and a tubular inner member each having a respective lumen. The inner member is at least partially disposed in the outer member lumen such that an outer surface of the inner member and an inner surface of the outer member together define an annular inflation lumen. The outer member has micropores or micro-holes configured such that when a contrast agent is injected into the inflation lumen, the micropores or micro-holes allow air to pass therethrough and thereafter become clogged by the contrast agent. The catheter also has a balloon member having its ends secured to and circumferentially around the outer member such that an inner surface of the balloon member and the outer surface of the outer member define an inflatable balloon interior.

The disclosure relates to devices and methods for the treatment of edema, which devices use a restrictor for flow compensation. Devices and methods of the invention further use a flow-restrictor in the circulatory system, upstream of an intravascular pump, to balance pressure changes induced by the pump and to compensate for downstream flow. The device may be provided as an indwelling, intravascular catheter with a mechanical pump such as an impeller and a selectively deployable restrictor such as an inflatable balloon. Congestive heart failure or edema is treated by \ operating the pump in an innominate vein and using the restrictor for flow compensation, to restrict the upstream flow and thus amplify or maintain pressure reduction at the lymphatic outlet.

Systems and methods and devices are provided for treating conditions such as heart failure and/or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient’s superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient’s Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure.

Superior dilatation devices and methods of using such devices are contemplated which are effective for providing enhanced levels of sexual stimulation as well as enhancing the treatment or amelioration of conditions which may be treated with dilatation, such as vaginismus and other forms of dyspareunia, pelvic floor dysfunction, and certain other forms of incontinence. By positioning a tubular balloon around the shaft of a conventional rigid dilatation device, providing a reservoir inside the body of the device containing an inflation fluid like helium gas, and using a pump to transfer the inflation between the two, the balloon may be inflated and deflated repeatedly and on command. Through particular control systems, potentially including biofeedback elements and arrangements of multiple balloon lumens, the inflation/deflation sequence may be customized and optimized to produce an enhanced stimulative or treatment effect.

A multi-lumen catheter for monitoring intramuscular pressure having an elongated body configured and dimensioned for insertion into a compartment of a patient. The catheter has a pressure sensor to determine if excessive pressure is being applied. A sensor is in communication with the lumen to continuously measure pressure to provide continuous readings of intramuscular pressure.

The present disclosure relates to a method for automatic evaluation of a filling volume of an oesophageal balloon catheter (26) inserted into a mechanically ventilated patient (3). The method comprises obtaining (S3-S4) samples of an airway pressure, P.sub.aw, and an oesophageal pressure, P.sub.es, of the patient during an occlusion period in which respiration of the patient is prevented, evaluating (S5) the filling volume of the oesophageal balloon catheter by determining a ratio, ΔP.sub.es/ΔP.sub.aw, between P.sub.es and P.sub.aw from a regression analysis of the P.sub.es and P.sub.aw samples, and communicating (S6) a result of the evaluation to a user.