Balloon guide catheter with a balloon bonded thereto maximizing bonding strength and integrity while minimizing outer profile. Reflow jacket(s) is melted to/embedded within a braid supporting structure of the catheter securing beneath the balloon. Radially arranged apertures and/or recesses may be defined in the balloon through which adhesive is seepable upwards when secured about the catheter shaft. Proximal and distal bond interface areas of the balloon may be skived at right angles into two sections each extending radially 180°. Proximal and/or distal edges of the balloon may be flipped inwards prior to securing to the catheter shaft to form respective proximal and/or inverted bonds. During prepping of the catheter, residual air may be purged from the balloon via an exhaust hole defined in the compliant balloon or an exhaust tube secured between the exterior surface of the catheter shaft and the balloon.

Provided is a treatment method of being able to improve the obstruction of a biological lumen caused by stenosis of the biological lumen and the stagnation of a secretion. The treatment method includes a disposition step of disposing a dilation portion that can be dilated and deflated, and a collection portion, which is capable of removing a secretion S secreted from a biological lumen from a living body, in a stenosed site occurring in the biological lumen; a dilation step of widening the stenosed site after the disposition step by dilating the dilation portion in the stenosed site after the disposition step; and a removal step of removing the secretion from the living body by a removal portion.

A scaffold is mounted on a balloon of a balloon catheter. The scaffold has closed cells which deform upon balloon expansion and generate forces that cause struts or other components of the scaffold to deflect outwardly to a diameter that is greater than the inflated diameter balloon. The deflected struts apply forces to fracture plaque of other hardened lesions and also form an annular gap surrounding the balloon to provide for bypass flow of blood or other body fluids. A sheath may be located over the deflected struts to protect adjacent tissue structures from the deflected struts and/or to further define the gap.

A medical device system includes a medical device that is configured to be delivered to a lesion area in a body lumen, a guide wire that is configured to guide the medical device, a port member that is configured to introduce the guide wire and the medical device into a living body, a proximal-end fixing member that is configured to fix the guide wire and the port member and is provided with an operation unit that is configured to cause the guide wire to move in an insertion/pulling-out direction from the fixed state, an anchor device provided with an anchor portion in a distal portion thereof, and an anchor-device guide wire that is configured to guide the anchor device.

The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded.

A medical device includes an expandable-and-contractible member capable of radially expanding and radially contracting, an incising member disposed on an outer circumference of the expandable-and-contractible member and having a hollow portion, a core wire inserted in the hollow portion, a distal tip, and a ring. The core wire is capable of sliding in a longitudinal direction of the medical device as the expandable-and-contractible member expands or contracts. The incising member is therefore not likely to come off upon radial expansion or radial contraction of the expandable-and-contractible member, and is therefore not likely to interfere with the expanding or contracting movement of the expandable-and-contractible member.

Balloon angioplasty catheters having cutting or scoring members that are moveable in at least one direction between a stowed position (away from the angioplasty balloon) and an operative position (on the angioplasty balloon). A balloon catheter of the present invention alternately useable to perform balloon dilation of a body lumen with and without concurrent cutting or scoring.

Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.

A clot capture catheter comprises an elongate tubular shaft having a proximal end, a distal end and an inflatable expansile member at the distal end. The expansile member is inflatable from a collapsed delivery configuration to an expanded configuration. In the expanded configuration, the expansile member extends to define a funnel shape having an enlarged distal clot entry mouth at the distal-most end of the catheter. In the expanded configuration, the expansile member may extend distally beyond the distalmost tip of the shaft. The expansile member may be integral with the distal tip of the catheter shaft.

Catheter based systems for isolated stenting of an intravascular lesion can include two expandable occlusion devices with a balloon expandable stent or self-expanding stent therebetween. Expandable occlusion devices can be expanded in a distal direction and a proximal direction in relation to the lesion to occlude vasculature. A treatment agent can be injected into a cavity formed between the expandable occlusion device. A coating can be applied to one or both occlusion devices to prevent adherence to the treatment agent. The stent can be deployed across the lesion while the occlusion devices are in place. Fragments dislodged during stenting can be aspirated.