Described herein is an implantable access port device with a catheter compartment which permits lengthening or shortening the catheter in response to changes in tension of the distal catheter. Implantable access port devices are used extensively in the medical field to facilitate the performance of recurrent therapeutic tasks such as repeated drug delivery, drainage, blood sampling, transfusions, or total parental nutrition. In current access port systems, the catheter is rigidly attached to the access port via a connection ring. As such, the system does not provide any flexibility or ability for catheter length adjustments, which can lead to long-term complications such as dislodgement of catheters, migration of catheters, port separation with extravasation, suture disruption, and mechanical failure of the access port system. These catheter-related complications carry serious risks for the patients. The implantable access port system described herein permits self-adjusting catheter length, thereby reducing catheter-related complications.

Disclosed are toggling vascular access port and methods of deploying thereof. The port includes a port body coupled with a septum member covering a cavity defined by the port body, and at least one port body extension restrictedly movable along an at least one defined route on the port body. The port is selectively changeable from a delivery configuration to a deployed configuration by moving the at least one port body extension along the at least one defined route wherein the at least one port body extension and the port body are approximated along a median plane of the port body and laterally opposing portions of the at least one port body extension are parted transversely to the median plane, thereby reducing length-to-width ratio of the toggling vascular access port.

Medical devices and methods for making and using medical devices are disclosed. An example medical device may include an access valve that may be retrieved after implantation. The access valve may include a frame having a lumen, a self-expandable member extending through the lumen, and an elastic membrane extending through the lumen and a second end of the frame to releasably seal the lumen. The access valve may releasably attach to a wall of a patient and releasably seal an opening through the wall. The access valve may be attached to the wall by placing the frame adjacent the wall, extending the self-expandable member through the opening in the wall, and expanding the self-expandable member such that the self-expandable member applies a first force against the wall and a second force opposite the first force against the frame to sandwich the wall between the self-expandable member and the frame.

The present invention relates to a disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the delivery assembly comprising: a disposable injector (60) comprising an injection needle (65), a flexible tube (64) and an injector fluid coupling (68), wherein the injection needle (65) is in fluid communication with the fluid coupling (68) via the flexible tube (64), a disposable cartridge (70) comprising a reservoir (80) at least partially filled with the liquid medicament and comprising a cartridge fluid coupling (90) in fluid communication with the reservoir (80), wherein the injector (60) and the cartridge (70) are mechanically interconnected in an undeployed configuration (4), in which the injector fluid coupling (68) and the cartridge fluid coupling (90) are disconnected, and—wherein the cartridge (70) is displaceable relative to the injector (60) into a deployed configuration (6), in which the injector fluid coupling (68) and the cartridge fluid coupling (90) are in fluid communication.

Subcutaneous access hub embodiments are discussed herein that include housing embodiments having a plurality of cannula ports and a fluid passageway network that allows fluid communication between a fluid source and the plurality of cannula access ports. Such a configuration may allow a user such as a patient or clinician to releasably secure the housing to an outside surface of the patient's skin. Multiple locations on the patient's skin may then be accessed for deployment of one or more delivery cannulas via a plurality of cannula ports for delivery of fluid and from the fluid source to multiple subcutaneous locations below the patient's skin and timely movement of cannula access in the patient's skin without the need for relocating the housing.

A vascular access device for haemodialysis permanently implantable in a patient having a pre-existing arteriovenous fistula or, alternatively, in a vein, an artery or between a vein and an artery, to create an artificial arteriovenous fistula and a vascular access healing device and a sterile package containing a single-use device of collecting and/or injecting blood usable in combination with the vascular access device.

An access port for providing subcutaneous access to a patient is disclosed. In one embodiment, the port includes an internal body defining a fluid cavity that is accessible via a septum. A compliant outer cover including silicone is disposed about at least a portion of the body. A flange is included with the port body and is covered by the outer cover. The flange radially extends about a perimeter of the port body proximate the septum so as to impede penetration of a needle substantially into the outer cover in instances where the needle misses the septum. The flange can further include both an anchoring feature for securing the outer cover to the port body and an identification feature observable via x-ray imaging technology for conveying information indicative of at least one attribute of the access port. The outer cover provides a suitable surface for application of an antimicrobial/antithrombotic coating.

Disclosed is an apparatus and method for facilitating the implantation and secure positioning of implantable medical devices within a subcutaneous pocket formed by a surgeon within the patient. Such apparatus and method are configured to address the above-described challenges of containing implantable medical devices within such subcutaneous pockets, and the spring-like leads or catheters that may be attached to them, during implantation.

The present invention relates to a disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the delivery assembly comprising: a disposable injector comprising an injection needle, a flexible tube and an injector fluid coupling, wherein the injection needle is in fluid communication with the fluid coupling via the flexible tube, a disposable cartridge comprising a reservoir at least partially filled with the liquid medicament and comprising a cartridge fluid coupling in fluid communication with the reservoir, wherein the injector and the cartridge are mechanically interconnected in an undeployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are disconnected, and wherein the cartridge is displaceable relative to the injector into a deployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are in fluid communication.

The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.