Embodiments provide for intracranial delivery of a medicinal solution to the brain. A system includes a bun hole stopple for insertion in a cranial bun hole, a catheter, a connecting member, a connector tube, and a pump. The catheter is advanced through an opening in the stopple to a tissue site in the brain. A proximal portion of the catheter is fixed to an outer groove in the stopple to minimize movement of the catheter in the brain. The catheter, connecting member, connector tube, and pump are fluidically coupled together to create a flow path between the pump and a distal end of the catheter for infusion of the medicinal solution to the tissue site in the brain.

A valving device includes a body with an inlet, an outlet and an internal fluid path extending from the inlet to the outlet. Within the internal fluid path, the valving device has a valve mechanism with an open mode that allows fluid flow through the valve mechanism between the inlet and outlet and closed mode that prevents fluid flow through the valve mechanism. The valve mechanism has a first surface facing the inlet and a second surface facing the outlet. The body at least partially defines a flow corral. The flow corral(s) is/are located distal to the valve mechanism and redirect fluid passing through the valving device back toward the second surface of the valve mechanism to flush the underside of the valve mechanism.

Systems, methods and devices are described including a catheter adapter subassembly including a magnetic feature. Systems include such a catheter adapter subassembly and a needle subassembly including a magnetic feature, and relative movement of the catheter adapter subassembly and the needle subassembly can be determined using a magnetometer.

A delivery adapter which may be used as an interface between a syringe and a catheter hub is described.

An improved method and device are provided for forming and/or maintaining a percutaneous access pathway. The device generally comprises an access pathway and attachment device. The provided assembly substantially reduces the possibility of iatrogenic infection while accessing and/or re-accessing a body space.

An implantable surgical device, comprising a body having an inner side separated from an outer side by a body thickness; the body comprising a rigid or semi-rigid portion having an opening disposed therethrough, bound by a perimeter, the body opening dimensioned to allow a portion of a patients bowel to extend therethrough; a plurality of flexible obturators positioned about the opening perimeter, each obturator engaged with, and extending away from the opening perimeter into the body opening, each obturator having an inner face separated from an outer face by a thickness; a portion of at least one obturator overlapping with a portion of an adjacent obturator located on either side of the at least one obturator. A system and method to use the device is also disclosed.

A tissue expander is disclosed herein. The tissue expander may comprise a shell defining a chamber, and having a flexible wall and a port disposed through the flexible wall. The shell may also include a channel disposed through the flexible wall. A first syringe containing a first volume of a liquid may be connected to the chamber of the tissue expander via the channel. A second syringe containing a second volume of the liquid may be connected to the chamber via the port at least approximately one week after the first volume of liquid is injected. The first volume of liquid may be injected more quickly than the second volume of liquid.

Set forth are the structure, function, placement, and applications of vascular valves and servovalves. In the vascular tree, the diversion, shunting, and bypass of flow these provide allow solid organ transplantation which eliminates anoxia and graft organ degradation following harvesting and storage, likely including late term cardiac allograft vasculopathy. Along the lower urinary tract, the diversion of urine from damaged ureters to the native or an artificial bladder or collection bag alleviates problems of intractable urinary incontinence, nocturia, overactive bladder, and frequent urination. Where the lower tract is missing, the synthetics in a valve-based prosthesis preclude infection and degenerative metaplastic transition which can result in malignancy when gut is used to construct a neobladder and/or high maintenance stoma. Accessory channels in side-entry valves and servovalves allow the direct pipe-targeting of medication to sites of disease, anastomoses, or any other trouble spots.

A system for attachment of a device to a bone is provided. The system includes an internal axial rod with a proximal and distal end that is configured to be inserted and secured into a bone cavity's distal end. The system can also include an internal-external transfer rod with a proximal and distal end mounted into the distal end of the axial rod and a central channel extending through the transfer rod from the proximal end to the distal end and a plurality of attachment rings for attaching at least one tissue or muscle group to the transfer rod. The system also includes a bio-compatible and bio-occlusive artificial membranes (BIOCAMS) lamina, wherein the lamina includes either a polyetheretherketone (PEEK) mesh, a biocompatible polymer, a carbon fiber polymer, an artificial tissue polymer, molded donor tissue, allogenic tissue, a collagen/hyaluronic acid-based tissue, or connective tissue biosynthetic substrate material suitable as webbing.

A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.