The present disclosure provides a method for imaging a compound contained by a lipid vesicle in water. The method comprises the following steps of: (a) providing an aqueous sample comprising the lipid vesicle which contains the compound, wherein the aqueous sample further comprises ammonium sulphate ((NH.sub.4).sub.2SO.sub.4); (b) illuminating the aqueous sample with an X-ray free-electron laser (X-FEL); (c) with an image sensor, collecting a plurality of coherent diffraction image patterns of the aqueous sample being illuminated; and (d) reconstructing the coherent diffraction image patterns with a computer such that an image of the lipid vesicle containing the compound is acquired. A method for examining a quality of a chemical drug contained by a liposome in water is also provided.

An apparatus for guiding, in particular directing or accelerating, charged particles (50), comprising: a substrate (110) having a surface (115); an optically thinner layer (120) formed on the surface (115); an inhomogeneous channel (130) which is formed by two mutually opposite delimiting structures on a side of the layer (120) that is opposite the substrate (110); and a radiation device which is designed to generate at least one pulsed laser beam (140) and inject the at least one pulsed laser beam (140) into the channel (130) from a side that is opposite the optically thinner layer (120). The layer (120) for the laser beam (140) is optically thin, and the delimiting structures have a high optical density in comparison with the layer (120). The delimiting structures are designed to guide the particles (50) by means of the laser beam (140) in the channel (130) and alternatingly focus them along the channel (130) and in at least one direction perpendicular to the channel (130).

A delivery system for use within a lithographic system. The beam delivery system comprises optical elements arranged to receive a radiation beam from a radiation source and to reflect portions of radiation along one or more directions to form a one or more branch radiation beams for provision to one or more tools.

An optical assembly guides an output beam of a free electron laser to a downstream illumination-optical assembly of an EUV projection exposure apparatus. The optical assembly has first and a second GI mirrors, each with a structured reflection surface to be impinged upon by the output beam. A first angle of incidence on the first GI mirror is between one mrd and 10 mrad. A maximum first scattering angle is produced, amounting to between 50% and 100% of the first angle of incidence. A second angle of incidence on the second GI mirror is at least twice as large as the first angle of incidence. A maximum second scattering angle of the output beam amounts to between 30% and 100% of the second angle of incidence. The two planes of incidence on the two GI mirrors include an angle with respect to one another that is greater than 45.

Systems for transmitting power to and from flight vehicles, and associated devices and methods are described herein. A representative flight power-transmission system includes a surface-based transmitter on or adjacent to the surface of the Earth, a flight platform remote from the surface-based transmitter, and a free electron laser (FEL) carried by the flight platform. The transmitter is configured to transmit electromagnetic radiation to the FEL, and the FEL is configured to receive at least a portion of the electromagnetic radiation from the FEL and generate a laser beam based at least in part on the received electromagnetic radiation. The flight platform can be an aerostat positioned at high altitude within the stratosphere. The FEL can direct the laser beam for one or more end uses, such as (i) supplying power to a downrange electric aircraft, (ii) supplying power to a surface-based receiver, (iii) providing directed-energy for destroying or disabling a target, and/or (iv) providing directed-energy for clearing orbital debris.

A method includes simulating diffraction in a transmission geometry of relativistic electron bunches from a crystallographic structure of a crystal thereby simulating diffraction of the relativistic electron bunches into a plurality of Bragg peaks. The method includes selecting a range of angles between a direction of propagation of the relativistic electron bunches and a normal direction of crystal including an angle at which a diffraction portion is maximized. The method includes sequentially accelerating a plurality of physical electron bunches to relativistic energies toward a physical crystal having the crystallographic structure and diffracting the plurality of physical electron bunches off the physical crystal at different angles and measuring the diffraction portion into the respective Bragg peak at the different angles. The method includes selecting a final angle based on the measured diffraction portion into the respective Bragg peak at the different angles and generating a pulse of light.

An apparatus for generating Smith-Purcell radiation having at least one spectral component at a wavelength includes a periodic structure including a dielectric material and an electron source, in electromagnetic communication with the periodic structure, to emit an electron beam propagating within about 5 from a surface of the periodic structure to induce emission of the Smith-Purcell radiation. The electron beam has an electron energy tunable between about 0.5 keV and about 40 keV so as to change a wavelength of the Smith-Purcell radiation.

A radiation sensor apparatus for determining a position and/or power of a radiation beam, the radiation sensor apparatus including a chamber to contain a gas, one or more sensors, and a processor. The chamber has a first opening and a second opening such that a radiation beam can enter the chamber through the first opening, propagate through the chamber generally along an axis, and exit the chamber through the second opening. Each of the one or more sensors is arranged to receive and detect radiation emitted from a region of the chamber around the axis. The processor is operable to use the radiation detected by the one or more sensors to determine a position and/or power of the radiation beam.

A method for varying the wavelength of a free electron laser (FEL) by applying an energy dither to the charged particles supplying the FEL. Bunches of charged particle beams are accelerated by cavities that are operated at a harmonic of the bunch repetition rate. The method involves adding one or more secondary radiofrequency accelerator cavities after the primary beam transport and near the wiggler to apply a fluctuation between individual bunches with a pseudo-random distribution. The secondary radiofrequency accelerator cavities provide fine variations of the beam energy about a nominal operating point. Operating a free electron laser (FEL) with a 1% change in the electron beam energy via the added secondary cavities will result in a 2% wavelength variation of the FEL output.

A helical permanent magnet structure includes at least one magnet assembly. The magnet assembly includes a plurality of permanent magnets and poles. The permanent magnets are with a magnetization direction, and formed as helical shape and arranged as a helical surface, the center of the helical surface has a longitudinal passage for being passed through by a charged particle. The poles are with the same amount of the permanent magnets, wherein the poles are magnetized by the permanent magnets and absorb on one side of the permanent magnets.