The present application discloses a cavity dumped low repetition rate infrared tunable femtosecond laser source configured to produce pulses of 200 femtoseconds or less with a peak power of four megawatts or more for use in a variety of applications including multi-photon microscopy.

A double-pulse laser system for generating first and second laser pulses, comprising a multipass cell (300) arranged to delay the second laser pulse with respect to the first laser pulse, wherein the multipass cell comprises first (305A, 305B) and second (307) reflector arrangements defining an optical cavity (315) in which the delayed second laser pulse is reflected back and forth multiple times between the first (305A, 305B) and second (307) reflector arrangements to provide a temporal delay between the first and second pulses of 1 ns or greater.

A double-pulse laser system for generating first and second laser pulses, comprising a multipass cell (300) arranged to delay the second laser pulse with respect to the first laser pulse, wherein the multipass cell comprises first (305A, 305B) and second (307) reflector arrangements defining an optical cavity (315) in which the delayed second laser pulse is reflected back and forth multiple times between the first (305A, 305B) and second (307) reflector arrangements to provide a temporal delay between the first and second pulses of 1 ns or greater.

Methods, systems and apparatus are disclosed for delivery of pulsed treatment radiation by employing a pump radiation source generating picosecond pulses at a first wavelength, and a frequency-shifting resonator having a lasing medium and resonant cavity configured to receive the picosecond pulses from the pump source at the first wavelength and to emit radiation at a second wavelength in response thereto, wherein the resonant cavity of the frequency-shifting resonator has a round trip time shorter than the duration of the picosecond pulses generated by the pump radiation source. Methods, systems and apparatus are also disclosed for providing beam uniformity and a sub-harmonic resonator.

Disclosed are system and methods for a laser system comprising at least one laser, a processor, and a user interface. The processor can receive a range for at least one setting of the at least one laser that the at least one laser can operate within. The processor can further determine a proposed updated value for the at least one setting and determine that the proposed updated value is within the range. An indication of the proposed updated value and an option for a user to accept or reject the proposed updated value can be provided on a user interface. Responsive to an acceptance the at least one setting can be adjusted based on the proposed updated value. Responsive to no rejection within a predetermined period of time, the processor can cause the at least one setting to be adjusted or cancel adjustment of the at least one setting.

Disclosed are system and methods for a laser system comprising at least one laser, a processor, and a user interface. The processor can receive a range for at least one setting of the at least one laser that the at least one laser can operate within. The processor can further determine a proposed updated value for the at least one setting and determine that the proposed updated value is within the range. An indication of the proposed updated value and an option for a user to accept or reject the proposed updated value can be provided on a user interface. Responsive to an acceptance the at least one setting can be adjusted based on the proposed updated value. Responsive to no rejection within a predetermined period of time, the processor can cause the at least one setting to be adjusted or cancel adjustment of the at least one setting.

A laser assembly is provided that includes a laser resonator that emits a first light having a first pulse width, and a trigger assembly electrically coupled to the laser resonator to actuate the laser resonator. The laser assembly also includes a sensor configured to detect the first light as the light emits from the laser resonator, and one or more processors coupled to the trigger assembly. The one or more processors are configured to obtain a first time delay interval from when the trigger assembly is actuated to when the sensor detects the first light, and actuate the laser resonator to emit a second light having a second pulse width based on the time delay interval determined.

A pump source configured to generate a pulsed optical beam. The pump source generates a first light beam, a second light beam, and a third light beam, where the first, the second, and the third light beams satisfy a phase relationship. Each of the first, the second, and the third light beams are independently modulated in separate modulation paths and recombined as a pulsed optical beam. A portion of the pulsed optical beam is parametrically amplified within a nonlinear optical medium, where a resulting amplification gain is proportional to a phase difference between the first, second, and third modulated light beams. The power value of the amplified beam is measured as an indication of the phrase difference between the three beams and a corrective phase adjustment based on the error correction signal is applied on any one of the first, second, and third modulation paths to maintain the phase relationship.

Methods, systems and apparatus are disclosed for delivery of pulsed treatment radiation by employing a pump radiation source generating picosecond pulses at a first wavelength, and a frequency-shifting resonator having a losing medium and resonant cavity configured to receive the picosecond pulses from the pump source at the first wavelength and to emit radiation at a second wavelength in response thereto, wherein the resonant cavity of the frequency-shifting resonator has a round trip time shorter than the duration of the picosecond pulses generated by the pump radiation source. Methods, systems and apparatus are also disclosed for providing beam uniformity and a sub-harmonic resonator.

In methods and devices for generating a laser pulse of an excitation laser that is actuated by a driver in response to a triggering time of a trigger signal, the driver actuation signal is generated taking into account the time interval between the triggering time and a preceding triggering time.