The present disclosure provides systems and methods for controlling gas-enrichment, e.g., oxygen-enrichment, therapy. One or more sensors and/or one or more imaging systems may be used to measure or determine one or more physiological parameters of the patient. Feedback regarding one or more physiological parameters or microvascular resistance may be provided for titrating or controlling the gas-enrichment therapy.

A cardiac pump is arranged to mimic triphasic operation. The pump uses a fluid line formed from flexible tubing, along with a reciprocating actuator arranged to move between a free orientation and an occluding orientation. This allows a portion of the fluid line to be selectively occluded during movement of the actuator, enabling blood or other fluids to be peristaltically forced fluid towards a fluid outlet. The direction of operation of the actuator, and the selection of appropriate occluding or free orientations, allows the pump to be operated in a triphasic manner.

A cardiac pump is arranged to mimic triphasic operation. The pump uses a fluid line formed from flexible tubing, along with a reciprocating actuator arranged to move between a free orientation and an occluding orientation. This allows a portion of the fluid line to be selectively occluded during movement of the actuator, enabling blood or other fluids to be peristaltically forced fluid towards a fluid outlet. The direction of operation of the actuator, and the selection of appropriate occluding or free orientations, allows the pump to be operated in a triphasic manner.

A blood pumping device having at least a first pump and a second pump, and a first and second pump actuating means for inducing a blood flow in a body's circulatory system is disclosed. Each pump comprises one upper chamber having an inlet channel and one lower chamber having an outlet channel. The upper and lower chambers are separated by a movable valve plane provided with a valve. The pump actuating means are configured to apply a movement to said valve plane in an upward and downward direction between said upper and lower chambers in response to control signals from a control unit, such that when said valve plane moves in an upward direction the valve provided in the valve plane is in an open position allowing a flow of blood from the upper chamber to the lower chamber, and when the valve plane moves in a downward direction the valve is in the closed position and blood is ejected from the lower chamber through the outlet channel. The bottom part of the bag portion has a shape that makes a turn of between 110° to 150° to cause blood entering the lower chamber to hit the stopping surface and come to a sudden stop, wherein the turn causes the flow of blood along the inner surface of the bag portion to abruptly change; and directs blood at the stopping surface to continue flowing along the outlet channel.

A cardiac pump is arranged to mimic triphasic operation. The pump uses a fluid line formed from flexible tubing, along with a reciprocating actuator arranged to move between a free orientation and an occluding orientation. This allows a portion of the fluid line to be selectively occluded during movement of the actuator, enabling blood or other fluids to be peristaltically forced fluid towards a fluid outlet. The direction of operation of the actuator, and the selection of appropriate occluding or free orientations, allows the pump to be operated in a triphasic manner.

A cardiac pump is arranged to mimic triphasic operation. The pump uses a fluid line formed from flexible tubing, along with a reciprocating actuator arranged to move between a free orientation and an occluding orientation. This allows a portion of the fluid line to be selectively occluded during movement of the actuator, enabling blood or other fluids to be peristaltically forced fluid towards a fluid outlet. The direction of operation of the actuator, and the selection of appropriate occluding or free orientations, allows the pump to be operated in a triphasic manner.

An extracorporeal cardiac assistance system, comprising a pump being configured to create a fluid flow from a suction line to a pressure line of the system; further comprising a control device configured to control the pump and/or an adjustable flow limiter to provide an adjustable flow rate and/or a pressure, wherein the control device is configured to execute a support mode with a plurality of consecutive support flow rate pulses and/or support pressure pulses interposed on the fluid flow and to execute a weaning mode with a plurality of such pulses, wherein an amount of energy provided to the fluid flow with each pulse is lower in the weaning mode than in the support mode.

An extracorporeal cardiac assistance system, comprising a pump being configured to create a fluid flow from a suction line to a pressure line of the system; further comprising a control device configured to control the pump and/or an adjustable flow limiter to provide an adjustable flow rate and/or a pressure, wherein the control device is configured to execute a support mode with a plurality of consecutive support flow rate pulses and/or support pressure pulses interposed on the fluid flow and to execute a weaning mode with a plurality of such pulses, wherein an amount of energy provided to the fluid flow with each pulse is lower in the weaning mode than in the support mode.

A method of assisting a heart of a patient using a dual lumen cannula includes inserting the dual lumen cannula into the patient, positioning a first infusion tube of the dual lumen cannula in an artery near the heart to pump blood thereto, positioning a second drainage tube of the dual lumen cannula in a chamber of the heart to drain blood therefrom. The dual lumen cannula has a plurality of infusion apertures extending through a sidewall of the first infusion tube at a distal end of the first infusion tube; and a plurality of drainage apertures extending through a sidewall of the second drainage tube at a distal end of the second drainage tube. The distal end of the first infusion tube has a tapered portion extending distally beyond a distal-most infusion aperture of the plurality of infusion apertures and to a terminal surface at a tip of the first infusion tube.

The invention relates to an arrangement having a blood pump and a gas exchanger for extracorporeal membrane oxygenation. According to the invention, the blood pump is designed as a pulsatile blood pump and is arranged with the gas exchanger in the same housing. The pulsatile blood pump and the gas exchanger are preferably connected to the same gas source so that the blood pump can be pneumatically driven. The novel ECMO system has a simple design, is flexible, and in particular can be used directly on the patient.