An implantable pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable pump, an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable pump. The implantable pump includes a flexible membrane coupled to an actuator assembly that is magnetically engagable with electromagnetic coils, so that when the electromagnetic coils are energized, the actuator assembly causes wavelike undulations to propagate along the flexible membrane to propel blood from through the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and/or platelet activation.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may reside outside the patient.

Apparatus and methods are described, including apparatus (20) for implanting in a heart of a human subject. The apparatus includes an interatrial anchor (22) shaped to define an opening (26) having a diameter of 4-8 mm, and a bag (24) in fluid communication with the opening of the anchor. The apparatus is shaped to fit within a right atrium of the heart of the subject, and has a capacity of between 4 and 20 cm3. Other applications are also described.

A motor drive controlling apparatus includes: a controller that generates and outputs a drive control signal, in response to input of a speed command signal and a rotational direction signal; a motor driver that generates and outputs a drive signal to a motor, in response to the drive control signal; and an encoder that detects a rotational position of the motor to output an encoder signal. The controller includes: a measurement unit that detects, based on the encoder signal, a time at which a rotational state of the motor becomes, caused by an external factor, different from that commanded by the speed command and rotational direction signals, and measures a movement amount from the time; and a transmitting unit that transmits, to the motor driver, a signal for stopping an output of the drive signal, when the movement amount and a drive-control-signal outputting state satisfy a predetermined condition.

A peristaltic pumping apparatus for use in blood processing procedures, comprising: a pump rotor rotatable about a rotational axis and a pump raceway circumferentially spaced about the axis; a pump cap disposed atop the pump rotor, the pump cap having a finger configured to engage a tubing loop of a length of tubing at a time of loading the tubing and guide the tubing loop within the raceway along the length of the tubing loop; and wherein the pump cap further comprises a tensioning wall disposed laterally opposite the finger, the tensioning wail configured to engage a length of the tubing loop at a time of unloading the tubing and provide tension to the tubing length as the tubing loop exits the raceway.

A pumping cassette including a housing having at least two inlet fluid lines and at least two outlet fluid lines. At least one balancing pod within the housing and in fluid connection with the fluid paths. The balancing pod balances the flow of a first fluid and the flow of a second fluid such that the volume of the first fluid equals the volume of the second fluid. The balancing pod also includes a membrane that forms two balancing chambers. Also included in the cassette is at least two reciprocating pressure displacement membrane pumps. The pumps are within the housing and they pump the fluid from a fluid inlet to a fluid outlet line and pump the second fluid from a fluid inlet to a fluid outlet.

A pumping assembly includes a flexible tube extending along a longitudinal axis. The flexible tube defines an internal cavity extending along the longitudinal axis. The internal cavity is configured to contain a fluid disposed therein, wherein the fluid is a liquid and/or a gas. A plurality of ferromagnetic or magnetic particles are disposed within at least a portion of a thickness of the flexible tube. The plurality of ferromagnetic or magnetic particles are also disposed extending along the longitudinal axis. A plurality of electromagnets are placed in series adjacent to one another. The flexible tube is disposed adjacent to the plurality of electromagnets. A controller is configured to selectively magnetize at least one electromagnet from the plurality of electromagnets in a progression along the plurality of electromagnets, thereby compressing the tubing in a progression being a pumping action. A power source is electrically connected to the controller.

A tubular pulsatile ventricular assist device (PVAD) system for providing forward flow of blood in a pulsatile, peristaltic, and non-hemolytic manner to help reduce the amount of blood clotting associated with current ventricular devices on the market. The system can encircle a portion of a blood vessel, and the system can sequentially apply a pressure through each port in a particular pre-determined patter so as to selectively occlude the lumen, thereby creating a pulsatile, peristaltic movement along a length of system. Said movement causes blood to flow through the portion of the blood vessel.

A tubular pulsatile ventricular assist device (PVAD) system for providing forward flow of blood in a pulsatile, peristaltic, and non-hemolytic manner to help reduce the amount of blood clotting associated with current ventricular devices on the market. The system can encircle a portion of a blood vessel, and the system can sequentially apply a pressure through each port in a particular pre-determined patter so as to selectively occlude the lumen, thereby creating a pulsatile, peristaltic movement along a length of system. Said movement causes blood to flow through the portion of the blood vessel.

An implantable pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable pump, an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable pump. The implantable pump includes a flexible membrane coupled to an actuator assembly that is magnetically engagable with electromagnetic coils, so that when the electromagnetic coils are energized, the actuator assembly causes wavelike undulations to propagate along the flexible membrane to propel blood from through the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and/or platelet activation.