A system for assisting a patient's heart has a pump, an oxygenator, a holder having a pump receiving portion for removably receiving the pump and an oxygenator receiving portion for removably receiving the oxygenator, and a harness configured to surround at least a portion of a patient's torso. The holder is connected to the harness. The system further has a brace connected to at least a portion of the harness. The brace is configured to extend behind a back portion of a user's head and to support tubing connected to at least one of the pump and the oxygenator. A priming tray and wet-to-wet connector connecting the cardiac assist system to the cannula so are also disclosed.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

A medical fluid pumping system includes a medical fluid pump for pumping a process fluid, the medical fluid pump including a first pump chamber, a first inlet valve chamber including a first inlet valve diaphragm, a first outlet valve chamber, a second pump chamber, a second inlet valve chamber including a second inlet valve diaphragm, and a second outlet valve chamber; and a medical fluid chassis operable with the medical fluid pump, the medical fluid chassis including a motive fluid source providing motive fluid at a motive fluid pressure, and wherein the first and second inlet valve diaphragms are configured to actuate from an open to a closed position at a pressure less than the motive fluid pressure to mitigate process fluid backflow through the first and second inlet valves.

A pump cassette is disclosed. The pump cassette includes a housing having at least one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump. The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.

A blood treatment system includes (i) a blood pump including a first blood pump chamber operable with a first inlet valve and a first outlet valve, and a second blood pump chamber operable with a second inlet valve and a second outlet valve; (ii) an arterial blood line; (iii) a dialyzer placed in fluid communication with the arterial blood line, wherein the blood pump is provided along the arterial blood line upstream of the dialyzer; and (iv) a venous blood line extending downstream from the dialyzer. The system also includes a processor configured to sequence the first and second blood pump chambers so as to achieve a pulsatile pattern of filling the first and second blood pump chambers and an at least substantially constant pattern of discharging blood from the first and second blood pump chambers to the dialyzer.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

A lid that retains a pump tube which is elastic; a finger driving unit that is disposed facing the lid with the pump tube interposed therebetween, and that causes a plurality of fingers to sequentially move in the direction of contacting and separating from the lid; and a pump tube opening/closing mechanism that causes the finger driving unit to advance towards and retract from the lid, and that closes and opens the pump tube which is disposed between the fingers and the lid.

A lid that retains a pump tube which is elastic; a finger driving unit that is disposed facing the lid with the pump tube interposed therebetween, and that causes a plurality of fingers to sequentially move in the direction of contacting and separating from the lid; and a pump tube opening/closing mechanism that causes the finger driving unit to advance towards and retract from the lid, and that closes and opens the pump tube which is disposed between the fingers and the lid.

Embodiments of the present invention relate generally to certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfectants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).