Hemodialysis and similar dialysis systems including a variety of systems and methods that make hemodialysis more efficient, easier, and/or more affordable, and include new fluid circuits for fluid flow in hemodialysis systems and a blood pump. The blood pump is configured to pump blood to a dialyzer of a hemodialysis apparatus and comprises a pneumatically actuated or controlled reciprocating diaphragm pump. The diaphragm of the pump comprises a flexible membrane formed or molded to conform to a curved inner wall of a pumping chamber or control chamber of the pump, and the diaphragm is pre-formed or molded to have a control side taking a convex shape, so that any elastic tension on the diaphragm is minimized when fully extended into a control chamber of the pump.

A hemodialysis system configured to purge air from a blood circuit comprising: a dialyzer; a dialysis fluid circuit operable with the dialyzer via dialysis fluid inlet and outlet lines; the blood circuit operable with the dialyzer and including an arterial line, a venous line, a blood pump operable with the arterial line upstream of the dialyzer, and a physiologically acceptable fluid source in fluid communication with the arterial line upstream of the blood pump; and an air purging scheme wherein, with the dialysis fluid inlet and outlet lines connected to the dialyzer, air is purged using dialysis fluid or other physiologically acceptable fluid pumped by at least one of the fresh or used dialysis fluid pumps from the dialysis fluid circuit, through the dialyzer, into the blood circuit, in combination with dialysis fluid or other physiologically acceptable fluid from the source introduced directly into the blood circuit.

The present invention relates to a method for temporarily interrupting an extracorporeal treatment of blood of a patient by use of a blood treatment apparatus. The method comprises activating or controlling a control device provided and configured to bring the blood treatment apparatus into a state in which the blood treatment session of the patient can be interrupted with the intention to continue the blood treatment session. The present invention further relates to a control device, a blood treatment apparatus, a digital storage means, a computer program product as well as a computer program.

The present invention relates to a method for temporarily interrupting an extracorporeal treatment of blood of a patient by use of a blood treatment apparatus. The method comprises activating or controlling a control device provided and configured to bring the blood treatment apparatus into a state in which the blood treatment session of the patient can be interrupted with the intention to continue the blood treatment session. The present invention further relates to a control device, a blood treatment apparatus, a digital storage means, a computer program product as well as a computer program.

A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.

A blood component sampling cassette which can be more efficiently manufactured at lower cost as compared to a typical cassette, a blood sampling circuit set, and a blood component sampling system. A blood component sampling cassette (22) includes a cassette main body (23) made of a soft material to which heat sterilization is applicable. The cassette main body (23) is provided with a retransfusion line (44). The retransfusion line (44) is provided with a reservoir (47) configured to temporarily store a blood component to be returned to a blood donor. The reservoir (47) is pressed by a retransfusion pump (49) to discharge the blood component from the reservoir (47).

Intravascular blood pumps and methods of use. The blood pump include a pump portion that includes a collapsible blood conduit defining a blood flow lumen between an inflow and an outflow. The pump portion includes a distal collapsible impeller axially spaced from a proximal collapsible impeller, at least a portion of each of the distal and proximal collapsible impellers disposed between the inflow and the outflow.

Intravascular blood pumps and methods of use. The blood pump include a pump portion that includes a collapsible blood conduit defining a blood flow lumen between an inflow and an outflow. The pump portion includes a distal collapsible impeller axially spaced from a proximal collapsible impeller, at least a portion of each of the distal and proximal collapsible impellers disposed between the inflow and the outflow.

A medical fluid delivery device includes (i) a process fluid body including first and second sides defining a first process fluid inlet valve seat and a first process fluid outlet valve seat and a second process fluid inlet valve seat and a second process fluid outlet valve seat; (ii) a first motive fluid plate defining a first aligned motive fluid inlet valve actuation area and a first aligned motive fluid outlet valve actuation area; (iii) a second motive fluid plate defining a second aligned motive fluid inlet valve actuation area and a second aligned motive fluid outlet valve actuation area; (iv) a first inlet valve diaphragm disposed between the first motive fluid inlet valve actuation area and the first process fluid inlet valve seat; and (v) a first outlet valve diaphragm disposed between the first motive fluid outlet valve actuation area and the first process fluid outlet valve seat.

A medical fluid pumping system includes (i) a medical fluid pump including a pump chamber, inlet and outlet valve chambers in fluid communication with the pump chamber, the pump chamber associated with a pumping chamber motive fluid connection, the inlet valve chamber associated with an inlet valve motive fluid connection, and the outlet valve chamber associated with an outlet valve motive fluid connection; (ii) a medical fluid chassis including a motive fluid source, and a first motive fluid connecting structure, a second motive fluid connecting structure, a third motive fluid connecting structure; and (iv) wherein the pumping chamber motive fluid connection, the inlet valve motive fluid connection, and the outlet valve motive fluid connection are translated simultaneously to mate respectively with the first motive fluid connecting structure, the second motive fluid connecting structure, and the third motive fluid connecting structure for fluid communication with the motive fluid source.