A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

Disclosed is a ventricular decompression and assisting apparatus (100). The apparatus (100) includes a pigtail and a catheter that is introduced percutaneously into a femoral/radial/brachial vein or artery and is advanced into the ventricle where blood is drawn and mechanically pumped back with an external blood pump (40) and pumped back downstream into the aorta (2) or venous system or the pulmonary artery using another suitable catheter from a second access into the femoral/radial/brachial artery or any vein and with tip thereof positioned at a desired location thus forming a ventricular vent loop. The desired cardiac circulation is maintained with smart pumping, monitoring and control while relieving the load on the heart muscle to rebuild strength thereof. The apparatus (100) provides user friendly simplified approach to ventricular venting and unloading as a means for mechanical circulatory support of the left heart, right heart or both circulations even simultaneously.

Disclosed is a ventricular decompression and assisting apparatus (100). The apparatus (100) includes a pigtail and a catheter that is introduced percutaneously into a femoral/radial/brachial vein or artery and is advanced into the ventricle where blood is drawn and mechanically pumped back with an external blood pump (40) and pumped back downstream into the aorta (2) or venous system or the pulmonary artery using another suitable catheter from a second access into the femoral/radial/brachial artery or any vein and with tip thereof positioned at a desired location thus forming a ventricular vent loop. The desired cardiac circulation is maintained with smart pumping, monitoring and control while relieving the load on the heart muscle to rebuild strength thereof. The apparatus (100) provides user friendly simplified approach to ventricular venting and unloading as a means for mechanical circulatory support of the left heart, right heart or both circulations even simultaneously.

The disclosure relates to a pump for implantation into a vessel or a heart, with the pump being introduced in a first state into the vessel or heart in order then be functionally changed over to a second state in the vessel or in the heart, having a drive part and a delivery part, where the drive part is not functional in the first state and becomes functional as a result of the changeover to the second state, wherein the drive part has an electric motor, where the electric motor is embodied as a wet rotor, and where, in the first state, the rotor of the electric motor and the stator of the electric motor are arranged so as to be separate from one another, and where the rotor of the electric motor is moved into the stator of the electric motor in the second state, where the rotor can drive the delivery part in the second state.

The invention relates to a blood treatment device having at least one metering line which opens into a fluid circuit, wherein a conveyor module is arranged in the metering line and comprises a membrane pump and a valve which is arranged at the pressure side thereof and which can act both as a blocking valve and as a restricting valve.

A dialysis system includes an on-line dialysate generator, a first dialysate pump in fluid communication with the on-line dialysate generator, and a second dialysate pump in fluid communication with the on-line dialysate generator. The dialysis system also includes a dialyzer in fluid communication with the first and second dialysate pumps. The dialysis system further includes a first valve located between the first dialysate pump and the dialyzer and a second valve located between the second dialysate pump and the dialyzer. The dialysis system is configured to alternate pumping of dialysate from the first and second dialysate pumps to the dialyzer using the first and second valves.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

A system for simulating cardiovascular fluid flow having a target fluid flow profile, which has target pulsatile flow and target systemic resistance components, in a test member is disclosed. The system includes a reservoir, a pump, input and output channels, a first valve in the input channel, a second valve in the output channel, and a processor. The input and output channels are connectable to the test member so as to form a fluid circuit with the test member. The processor is configured to execute a method for controlling the first valve to generate the target pulsatile flow component in the input channel, and controlling the second valve to generate the target systemic pressure component. Other systems are also disclosed. Methods for simulating target fluid flow profiles in a test member are also disclosed.

A system for simulating cardiovascular fluid flow having a target fluid flow profile, which has target pulsatile flow and target systemic resistance components, in a test member is disclosed. The system includes a reservoir, a pump, input and output channels, a first valve in the input channel, a second valve in the output channel, and a processor. The input and output channels are connectable to the test member so as to form a fluid circuit with the test member. The processor is configured to execute a method for controlling the first valve to generate the target pulsatile flow component in the input channel, and controlling the second valve to generate the target systemic pressure component. Other systems are also disclosed. Methods for simulating target fluid flow profiles in a test member are also disclosed.

A pumping cassette including a housing having at least two inlet fluid lines and at least two outlet fluid lines. At least one balancing pod within the housing and in fluid connection with the fluid paths. The balancing pod balances the flow of a first fluid and the flow of a second fluid such that the volume of the first fluid equals the volume of the second fluid. The balancing pod also includes a membrane that forms two balancing chambers. Also included in the cassette is at least two reciprocating pressure displacement membrane pumps. The pumps are within the housing and they pump the fluid from a fluid inlet to a fluid outlet line and pump the second fluid from a fluid inlet to a fluid outlet.