A connection apparatus for sealing to a pathway of a mounting structure includes a body; and a port including a threaded portion extending from the body and a non-threaded portion extending from the threaded portion, the non-threaded portion carrying a gasket, the gasket positioned along the non-threaded portion such that the mounting structure to which the connection apparatus is mounted contacts the gasket prior to the threaded portion engaging a mating threaded portion of the mounting structure, the port providing fluid communication between the body and the pathway of the mounting structure. The body may be that of a valve that supplies any of air, water or oil as an operating fluid to, for example, inlet and outlet valves and a pump chamber of a medical fluid pump of a medical fluid delivery machine.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

The invention relates to a pulsatile medical device enabling a blood flow to be circulated including an external pipe presenting an inside wall, an outside wall, and two ends, one end being for connection to an ECC type machine, to a cardiac assistance system or to the patient's body, and one end being for connection to the patient's body; an internal pipe inserted in said external pipe and presenting an inside wall, an outside wall, and two ends fastened all around their peripheries to the external pipe all around its periphery, the blood flow passing through said internal pipe; the outside wall of the internal pipe and the inside wall of the external pipe defining a space for filling with fluid and being connectable via a connector port to an appliance for creating one or more inflations/deflations of said space, thereby creating one or more pulses in the blood flow.

Embodiments of the present invention relate generally to certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as pods, pump pods, or pod pumps) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfactants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).

A hemodialysis system comprising: a source of priming fluid; an extracorporeal circuit including an arterial line, a venous line, and a drip chamber; a level sensor operable with the drip chamber; a reversible blood pump operable with the extracorporeal circuit; a connection between the arterial and the venous line; and a priming sequence in which priming fluid from the source is pumped in a reverse pump direction through the extracorporeal circuit and reversibly in a normal pump direction through the extracorporeal circuit, wherein an output from the level sensor is used to determine when to stop pumping in at least one of the directions.

A pumping cassette including a housing having at least two inlet fluid lines and at least two outlet fluid lines. At least one balancing pod within the housing and in fluid connection with the fluid paths. The balancing pod balances the flow of a first fluid and the flow of a second fluid such that the volume of the first fluid equals the volume of the second fluid. The balancing pod also includes a membrane that forms two balancing chambers. Also included in the cassette is at least two reciprocating pressure displacement membrane pumps. The pumps are within the housing and they pump the fluid from a fluid inlet to a fluid outlet line and pump the second fluid from a fluid inlet to a fluid outlet.

A renal therapy system includes: a filter; an arterial blood flowpath in fluid communication with the filter; a venous blood flowpath in fluid communication with the filter; a renal therapy fluid flowpath in fluid communication with the filter; first and second renal therapy fluid pumps; a plurality of valve actuators; and a dialysis fluid cassette including a plurality of valve portions configured to operate with the plurality of valve actuators so that (i) the first renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath for a number of first pump actuations, and (ii) the second renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath for a number of second pump actuations.

A medical fluid delivery machine includes a medical fluid pump, at least one of a positive air pressure source or a negative air pressure source for supplying positive or negative pressure air, a pneumatic manifold including an air passageway, a pneumatic valve, and a bracket. The pneumatic valve defines a valve aperture sized and arranged such that when the pneumatic valve is abutted against the pneumatic manifold, the valve aperture engages the manifold aperture, the pneumatic valve including a gasket that extends around the valve aperture.

A medical fluid delivery machine includes a medical fluid pump, at least one of a positive air pressure source or a negative air pressure source for supplying positive or negative pressure air, a pneumatic manifold including an air passageway, a pneumatic valve, and a bracket. The pneumatic valve defines a valve aperture sized and arranged such that when the pneumatic valve is abutted against the pneumatic manifold, the valve aperture engages the manifold aperture, the pneumatic valve including a gasket that extends around the valve aperture.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.