In various embodiments, a catheter pump is disclosed herein. The catheter pump can include an elongated catheter body having a distal portion including an expandable cannula having an inlet and an outlet. The expandable cannula can have a delivery profile and an operational profile larger than the delivery profile. An impeller assembly can include an impeller shaft, and an impeller body can include one or more blades. The impeller blades can draw blood into the cannula when rotated. Further, an expandable support can have a mounting portion disposed on the impeller shaft distal of the impeller body and a cannula contact portion for reducing a change in tip gap due to bending of the cannula. The cannula contact portion can be disposed distal of the mounting portion.

A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.

A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.

Improvements to intracardiac devices such as intracardiac blood pump assemblies, and associated methods. In one example, the present technology includes systems and methods for pacing the heart, and/or performing cardiac ablation using electrodes mounted on a portion of the intracardiac device. In another example, the present technology includes systems and methods for detecting mural thrombi in a patient's heart using electrical sensors or ultrasonic phased arrays mounted on the intracardiac device. In another example, the present technology includes systems and methods for detecting tissue changes and reactions in heart tissue during treatment using one or more temperature sensors. In another example, the present technology includes an improved distal tip for use with an intracardiac device. In another example, the present technology includes systems and methods for maintaining an intracardiac device in a desired position within a patient's heart using magnets or ultrasonic phased arrays mounted on the intracardiac device.

An extracorporeal circulation management device pumps blood in synchronization with heartbeats of a patient based on measurements of blood flow. Maximum and minimum blood flow measurement samples are compared with upper and lower threshold values to identify candidate timing for a systolic phase and diastolic phase of the heartbeat. During pulsatile pumping of the blood using the candidate timing, differences in the pulsatile flow measurements are determined. Based on the size of the difference, a final correction may be made to identification of the systolic and diastolic phases, and the corrected phase information is used to start and stop the motor unit.

An extracorporeal circulation management device pumps blood in synchronization with heartbeats of a patient based on measurements of blood flow. Maximum and minimum blood flow measurement samples are compared with upper and lower threshold values to identify candidate timing for a systolic phase and diastolic phase of the heartbeat. During pulsatile pumping of the blood using the candidate timing, differences in the pulsatile flow measurements are determined. Based on the size of the difference, a final correction may be made to identification of the systolic and diastolic phases, and the corrected phase information is used to start and stop the motor unit.

Described herein are devices and methods for pumping blood in a patient in need of circulatory assistance or a replacement heart. Instead of providing a temporary solution for these patients, the devices may be permanently implanted. The devices linearly reciprocate a shuttle within a housing to move blood into and out of the housing, and rotate the shuttle to selectively direct the movement of blood into and out of a plurality of ports in the housing.

Described herein are devices and methods for pumping blood in a patient in need of circulatory assistance or a replacement heart. Instead of providing a temporary solution for these patients, the devices may be permanently implanted. The devices linearly reciprocate a shuttle within a housing to move blood into and out of the housing, and rotate the shuttle to selectively direct the movement of blood into and out of a plurality of ports in the housing.

A percutaneous circulatory support device includes a housing, a cannula coupled to the housing, the cannula having a first portion and a second portion, and wherein the cannula includes at least one slot disposed along at least the first portion of the cannula, the at least one slot configured such that the first portion of the cannula is defined by a first stiffness and a second portion of the cannula is defined by a second stiffness, the first stiffness being different than the second stiffness.

An introducer sheath for use in delivering devices includes a proximal portion opposite a distal portion and a body portion extending between the proximal portion and the distal portion, the body portion defining a lumen of the introducer sheath configured for receiving at least one device, at least one bypass opening positioned in the proximal portion of the introducer sheath such that the bypass opening extends from an exterior of the introducer sheath to the lumen of the introducer sheath, and at least one plug configured to positioned within the lumen of the introducer sheath and to inhibit the flow of blood into the lumen proximal of the plug.