An improved system for supporting (e.g., localization and/or positioning of) intravascular devices discussed herein provides for example a multi-element arrangement. A set of struts optionally projects from the intravascular device and contacts the vessel walls. The localization and positioning of the pump may be provided by the struts and/or by use of a tether opposing a propulsive force to ensure localization.

A vascular coupling device (10), comprising a first and a second coupling element (21, 22) wherein each one of said first and second coupling elements (21, 22) has an external surface (23′, 23″) facing an external side, a coupling surface (25′, 25″) facing a coupling side, a central opening (27′, 27″), and a first and a second tubular connecting element (31, 32). Each one of said first and second tubular connecting elements (31, 32) is arranged in a corresponding central opening (27′, 27″) of the first and second coupling elements (21, 22) respectively, and with second open ends (37, 38) protruding through said central openings (27′, 27″) on said external side of each of said first and second coupling elements (21, 22). The first and second coupling elements (21, 22) being removably connected to each other into a locked configuration, or disconnected from each other into an unlocked configuration by means of a first and second locking structure (41, 42) being arranged on a centerline A and opposite to each other on an outer perimeter of said vascular coupling device (10). The vascular device further comprises a fail-safe arrangement comprising first and second cut-in portions (91, 92) arranged on said first coupling element (21) configured to receive first and second projecting elements (93, 94) arranged on said second coupling element (22), thereby preventing erroneous connection of said first and second coupling elements (21, 22) to each other.

Implantable devices may include a single, first component or a plurality of components such as first and second components, the second component being flexibly coupled to the first component. A socket extends over one or more of the component(s), the socket being configured to enhance the inter-component interaction and/or including one or more exposed surface(s) configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses.

Implantable devices may include a single, first component or a plurality of components such as first and second components, the second component being flexibly coupled to the first component. A socket extends over one or more of the component(s), the socket being configured to enhance the inter-component interaction and/or including one or more exposed surface(s) configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses.

An unloading blood pump includes a casing suitable for being incorporated into a human body, a turbine rotated by a rotor, a pumping chamber body mounted in a casing housing the turbine, an inlet port for sucking the blood from a suction cannula to the pumping chamber body and an outlet port for expelling blood from the pumping chamber to a reinjection cannula, wherein the pump is configured, depending on its power supply, to allow a nominal constant continuous flow of between 0.05 L/min and 0.5 L/min in order to reduce a capillary pressure of the lungs and/or of the left atrium and/or of the left ventricle.

Disclosed is a minimally invasive miniaturized percutaneous mechanical circulatory support system. The system may be placed across the aortic valve via a single femoral arterial access point. The system includes a low profile axial rotary blood pump carried by the distal end of a catheter. The system can be percutaneously inserted through the femoral artery and positioned across the aortic valve into the left ventricle. The device actively unloads the left ventricle by pumping blood from the left ventricle into the ascending aorta and systemic circulation. A magnetic drive and encased motor housing allows for purgeless operation for extended periods of time to treat various ailments, for example more than six hours as acute therapy for cardiogenic shock.

Disclosed is a mechanical circulatory support system for transcatheter delivery to the heart, having a removable guidewire aid to assist with inserting the guidewire along a path that avoids a rotating impeller. The system may comprise a catheter shaft and a circulatory support device carried by the shaft. The device may comprise a tubular housing, an impeller and the guidewire aid. The guidewire aid may include a removable guidewire guide tube. The guide tube may enter a first guidewire port of the tubular housing, exit the tubular housing via a second guidewire port on a side wall of the tubular housing on a distal side of the impeller, enter a third guidewire port on a proximal side of the impeller, and extend proximally through the catheter shaft.

A device to assist the performance of a heart with at least one pump that is formed as a rotary pump and driven via a magneto coupling.

A device to assist the performance of a heart with at least one pump that is formed as a rotary pump and driven via a magneto coupling.

A method of fixating an implantable heart help device in a human patient is provided. The method comprises the steps of: cutting the skin of said human patient, dissecting an area of the body comprising bone, and fixating said implantable heart help device to said part of the body comprising bone.