The invention relates to a device for treating an individual suffering from cardiac or circulatory arrest or from a stroke, comprising a blood withdrawal device (BE) that is applied to the individual (P), an analysis unit (BA) which is directly or indirectly connected to the blood withdrawal device for detecting a blood analysis result (BAE) providing at least one characteristic of the blood, directly or indirectly connected to a blood return device (BR) that is applied to the individual (P) and is designed to deliver a substance to the individual via the return device (BR).

An analyte monitoring system and method for an on-body sensor control device may have a capability for sensing two or more analytes of a patient includes a processor and memory with instructions for determining various machine states and outputs based on time-correlated sensor data for each of the analytes. The states and outputs may include: an alert condition for one or more analytes; an advisory message; a correction to an analyte state estimate; an indication of a malfunction of the sensor control device, a malfunction of an insulin delivery device, a medication dose calculation; or an analytical report. Examples of the system and method for dual analytes comprising glucose and ketone are described. Data may be transmitted from the sensor control device to a reader device for output to a user.

Provided are an insulin patch control method and apparatus. An insulin patch control method according to an embodiment of the present disclosure includes obtaining blood sugar information measured by a blood sugar sensor, from the insulin patch, inputting the obtained blood sugar information to a first neural network, estimating a pump parameter of the insulin patch based on output data from the first neural network, and performing a simulation of the insulin patch by inputting the blood sugar information and the pump parameter into a second neural network.

Rapidly administered emergency drug therapy represents life-saving treatment for a range of acute conditions including hypoglycemia, anaphylaxis, and cardiac arrest. A miniaturized (e.g., <3 cm.sup.3), lightweight (e.g., <2 g), minimally invasive fully wireless, emergency rescue device for the storage and active burst-release of indefinitely stable particulate forms of peptide and hormone drugs into subcutaneous sites for direct reconstitution in interstitial biofluids is disclosed. The device demonstrates a fast (e.g., <5 minutes) therapeutic effect. The device may deliver a drug across fibrotic tissue, which commonly accumulates following in vivo implantation, thereby accelerating systemic delivery. Fully wireless delivery of dry particulate glucagon in vivo is demonstrated, providing emergency hypoglycemic rescue in diabetic mice. Additionally, triggered delivery of epinephrine is demonstrated in vivo. Additionally, disclosed herein is a platform for the long-term in vivo closed loop delivery of emergency rescue drugs.

An automated, closed-loop gravity infusion system including a fluid source, a drop counter operatively engaged with a drip chamber of the fluid source, a roller clamp functionally linked with the drop counter, a processor operably engaged with the roller clamp, and a human-machine interface (HMI) functionally linked with the processor. Patient data is accessed by the HMI. The system utilizes the patient data and data from the drop counter to determine an appropriate roller clamp position. The drop counter continuously monitors the drip chamber's drip rate and feeds the data to the processor which then analyzes the data and automatically adjusts the roller clamp's position to provide an appropriate fluid dosage to the patient. The HMI is functionally linked to a remote centralized computing system configured to simultaneously monitor several identical systems, each of which is being used to infuse a different patient.

Systems and methods disclosed herein relate to a disease management device which includes at least one or more medication bladders, configured to store fluid and a medication delivery pump, configured to deliver a fluid from one or more medication bladders to a patient. Each medication bladder has at least a rigid portion and a flexible portion, the flexible portion coupled to the rigid portion to create an at least partially sealed enclosure. The rigid portion includes structures, such as channels, configured to facilitate emptying the medication bladder through an output port. On application of pressure from the pump, the flexible portion is configured to generate a pressure against the structures rigid portion, which facilitates emptying of fluid from the medication bladder through the output port.

An apparatus used in analyzing spent dialysate includes: at least one surface configured to accommodate a dialysate drain bag or drain line in a predetermined position; a light source positioned to emit light through the dialysate drain bag or drain line; and a light sensor positioned to sense light emitted by the light source through the dialysate drain bag or drain line.

A medical liquid injection device is provided. The medical liquid injection device includes a base body, a needle assembly mounted on the base body, a reservoir fluidly connected to the needle assembly and having a guide groove on an inner surface, and a driving unit configured to move a plunger disposed inside the reservoir.

A delivery device (10) for delivering medicament, such as insulin, to a patient includes a barrel (20), a delivery mechanism (12), and a pump assembly (14). The pump assembly includes a plunger (54), a drive member (56) and a drive screw (58). The plunger is able to slide within a barrel of the device independently of the drive plate. In one embodiment, the plunger is able to slide axially on the drive screw. The medication, such as insulin, can be introduced to the barrel (20) to fill the device and force the plunger to move axially in the barrel into engagement of the drive plate. The drive plate has a threaded aperture that mates with the drive screw. The drive plate engages the plunger by rotation of the drive screw to dispense the medication.

A system for selectively supplying a substance to a person, for regulating the concentration of glucose in the blood of a person, includes a device for selectively supplying a substance which includes a port for connecting to a transport element, and a controller for controlling the device, an infusion set including an infusion element comprising a first connector for connecting to a second connector of the transport element, and a transport element including second and third connectors. The following parts of the system can form at least one pair: the infusion elements; the second connectors; second connector with said or a respective third connector; or combinations thereof. The device can detect and/or be inputted with information indicating the pair is formed, and the controller controls the device such that a priming function can only be performed if detected and/or inputted that said at least one pair is formed.