The present invention relates to an automated stimulation device for inducing a tactile inter-stimulus onset asynchrony (ISOA) effect in a subject suffering from apnea, bradycardia and/or hypoxia, the device comprising at least two actuators configured for contacting a body portion of the subject, and interspaced for producing an apparent tactile movement in the subject upon sequential induction of actuation, wherein the duration of the actuations and the overlap in actuation time between the at least two actuators is controlled to attain an inter stimulus onset asynchrony (ISOA).

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

A steerable medical catheter includes a tubular body having a longitudinal axis and a distal portion for insertion into a subject, a first pull wire, a second pull wire, and a piezoelectric transducer. The piezoelectric transducer includes a first electrode and a second electrode. At the distal portion of the catheter the first pull wire and the second pull wire are each mechanically coupled to the tubular body at respective first and second offset positions with respect to the longitudinal axis for imparting a curvature on the distal portion of the catheter. At the distal portion of the catheter the first pull wire is electrically connected to the first electrode of the piezoelectric transducer and the second pull wire is electrically connected to the second electrode of the piezoelectric transducer.

A guiding sheath assembly has an elongated shaft, and a control handle with a control knob and a shuttle configured for translation in response to manipulation of the control knob. The assembly includes a puller wire extending along the shaft and responsive to translation of the shuttle to deflect the shaft. The puller wire has a stop at its proximal end wherein a deflection sensor is affixed to stop subject to compression between to generate a signal in response to distortion between the first shuttle and the first stop. A catheter having a control handle and a control knob for manipulation of a deflection puller wire whose proximal end is affixed to a stop anchored in the control handle housing includes a strain gauge affixed to the stop configured to detect deformation resulting from actuation of the puller wire in deflecting the catheter shaft. A drip chamber.

Systems include a receiving port configured to receive a cartridge configured to store a material capable of being aerosolized, a sensor configured to generate one or more measurements based on ambient conditions of a housing, an aerosolizer configured to aerosolize the material in response to receiving a signal, and a controller comprising one or more processors configured to generate the signal provided to the aerosolizer, and further configured to control operation of the aerosolizer via the signal.

A user interface of a respiratory therapy system includes a strap assembly, a frame, a connector, and a sensor. The strap assembly is positioned about a head of a user when the user wears the user interface. The frame is physically and electrically connected to the strap assembly, and defines an aperture. The connector has a first end portion and second end portion. The first end portion of the connector can be positioned within the aperture of the frame such that the connector is physically and electrically connected to the frame. The sensor is coupled to the strap assembly or the frame such that the sensor abuts a target area of the user when the user wears the user interface.

Medication delivery devices are provided having a dose delivery sensing capability. A sensed element is attached to a dose setting member of the device. The sensed element includes surface features radially-spaced from one another. A rotational sensor is attached to an actuator of the device. The rotational sensor includes a movable element that is contactable against the surface features. The rotational sensor is configured to generate a signal in response to the movement of the movable element over the surface features during their rotation. A controller is operatively coupled to the rotational sensor, and in response to receiving the generated signal, the controller is configured to determine a number of the surface features passing the movable element of the rotational sensor during dose delivery. The number can be associated with an amount of dose delivered. Sensing can be provided in a module or integrated in device.

A portable nebulizer and a vertical-type medicine containing and nebulizing assembly thereof are provided. The vertical-type medicine containing and nebulizing assembly includes a medicine storage module, a nebulizing module and an induction module. The nebulizing module includes a nebulizing device and a first conductive structure. The induction module includes a metal induction element disposed in the medicine storage module and a second conductive structure electrically connected to the metal induction element. The medicine storage casing has an inner surrounding area located in the medicine storage space. The metal induction element has an exposed induction portion exposed on the inner surrounding area for receiving a signal generated by the nebulizing device. Therefore, when a predetermined medicinal liquid contained in the medicine storage space is nebulized through the nebulizing device, the signal generated by the nebulizing device can be transmitted to a microprocessor through the induction module.

An infusion system for subcutaneous delivery of a fluid to a subject is disclosed. The infusion system comprises a source of a fluid; a fluid delivery system; a first fluid conduit in fluid communication with the source of the fluid and the fluid delivery system; a fluid injection device configured to be inserted into the skin of a subject for delivering the fluid to the subject; a second fluid conduit in fluid communication with the fluid delivery system and the fluid injection device; and a support frame attached to the source of the fluid and the fluid delivery system, wherein the support frame is configured to mount the source of the fluid and the fluid delivery system on a region of a head of the subject. The fluid delivery system moves the fluid from the source of the fluid, through the first fluid conduit, through the second fluid conduit, and through the fluid injection device.

Detection of unintentional air leaks in a user interface (e.g., mask) of a respiratory therapy system (e.g., a positive air pressure device) is disclosed. One or more sensors (e.g., within a computing device, such as a smartphone) can be moved around relative to the user interface to determine a location and/or intensity of an air leak. The computing device can provide feedback regarding the location and/or intensity of the air leak to facilitate the user locating the air leak, and thus correcting the air leak. In some cases, augmented reality annotations can be overlaid on an image (e.g., live image) of the user wearing the user interface to identify the location of the air leak. The system can automatically detect the type of user interface being used and can provide tailored guidance for reducing the air leaks.