One aspect of the present disclosure is directed to a device for providing light to the surface of a subject, comprising an array of a plurality of light emitting modules, wherein the plurality comprises four light emitting modules, each module of the plurality is flexibly connected to another module of the plurality, and two of the modules of the plurality comprise a polygonal perimeter having 4, 5, or 6 major sides, a light source, and a longest apex-to-apex dimension for a module of 5-50 millimeters, and, optionally, a non-adherent member configured to be adjacent to the subject.

A water electrolysis device for generating hydrogen gas includes a case, a power supplying unit, and an ion-exchange membrane electrolyzer. The case has a containing space including a bottom space and a top space. The bottom space is larger than the top space. The power supplying unit is configured in the bottom space for supplying power to operate the water electrolysis device. The ion-exchange membrane electrolyzer includes an ion-exchange membrane and a cathode, and the cathode generates hydrogen gas during which the ion-exchange membrane electrolyzer electrolyzes water.

A method for performing a photopheresis procedure is provided comprising collecting MNCs in a suspension comprising RBCs and plasma and lysing the red blood cells in the solution, preferably by combining the suspension with a solution to cause lysis. In one example, the solution for causing lysis of the red blood cells comprises ammonium chloride, and the suspension including the ammonium chloride is incubated to cause lysing. After lysing, the suspension may be washed to remove plasma and hemoglobin freed by the lysis of the red blood cells, and an ultraviolet light activated substance is added to the suspension. The suspension is then irradiated with ultraviolet light.

An implantable blood pump including a housing having an inlet cannula, a rotor disposed within the housing, the rotor in fluid communication with the inlet cannula, a stator disposed within the housing, the stator configured to rotate the rotor when a current is applied to the stator, and at least one ultraviolet light emitter disposed within the housing.

An apparatus for destroying cancer cells in blood includes a vessel for accepting a flow of blood of a patient through the vessel, and a sound energy source coupled with the vessel for generating sound energy at a resonant sweep frequency that causes cancer cells, within the flow of blood in the vessel, to act as cavitation nuclei and implode without implosion of other cells not resonant with the resonant sweep frequency. A method for destroying cancer cells in blood includes circulating blood from a patient through a vessel coupled with a sound energy source and exposing the blood, when passing through the vessel, to sound energy at a resonant sweep frequency to make cancer cells therein act as cavitation nuclei and implode without implosion of other cells not resonant with the resonant sweep frequency.

One aspect of the present disclosure is directed to a device for providing light to the surface of a subject, comprising an array of a plurality of light emitting modules, wherein the plurality comprises four light emitting modules, each module of the plurality is flexibly connected to another module of the plurality, and two of the modules of the plurality comprise a polygonal perimeter having 4, 5, or 6 major sides, a light source, and a longest apex-to-apex dimension for a module of 5-50 millimeters, and, optionally, a non-adherent member configured to be adjacent to the subject.

A system for imploding leukemia cells of a patient includes (a) a first vessel for containing a volume of blood received from the patient, and (b) drive circuitry cooperatively coupled with at least one transducer to produce ultrasound energy that spatially decoheres and disperses throughout the volume, to implode the leukemia cells throughout the volume via absorption of the ultrasound energy by the leukemia cells. The transducer may be an immersible transducer configured to be immersed in the blood. The system may include a second vessel for containing a liquid, within which the ultrasound energy is decohered and dispersed and from which at least a portion of the ultrasound energy is transmitted to the first vessel to implode the leukemia cells.

A photopheresis system (200) is disclosed, and that may be configured to execute one or more protocols. These protocols include: 1) protocols (400; 430; 460) for purging air out of a centrifuge bowl (210) used by the photopheresis system (200); 2) protocols (500; 510 550) for assessing the installation/operation of one or more pressure domes (330) used by the photopheresis system (200); and 3) protocols (580; 600; 660; 700; 740) for collecting buffy coat from blood processed by the photopheresis system (200).

A photopheresis system (200) is disclosed, and that may be configured to execute one or more protocols. These protocols include: 1) protocols (400; 430; 460) for purging air out of a centrifuge bowl (210) used by the photopheresis system (200); 2) protocols (500; 510 550) for assessing the installation/operation of one or more pressure domes (330) used by the photopheresis system (200); and 3) protocols (580; 600; 660; 700; 740) for collecting buffy coat from blood processed by the photopheresis system (200).

A surgical gas delivery system is disclosed for gas sealed insufflation and recirculation, which includes a gaseous sealing manifold for communicating with a gas sealed access port, an insufflation manifold for communicating with the gas sealed access port and with a valve sealed access port, a compressor for recirculating gas through the gas sealed access port by way of the gaseous sealing manifold, a first outlet line valve associated with the insufflation manifold for controlling a flow of insufflation gas to the gas sealed access port, a second outlet line valve associated with the insufflation manifold for controlling a flow of insufflation gas to the valve sealed access port, and a proportional valve associated the insufflation manifold and located upstream from the first and second outlet line valves for dynamically controlling the flow of insufflation gas to the first and second outlet line valves.