A device comprising a housing having a handle end and a treatment end. The treatment end is configured to provide an antimicrobial treatment and a heat treatment. The treatment end comprises an applicator having an applicator surface for providing at least the heat treatment. The device includes a heat generation unit configured to heat the applicator surface in use, a source of antimicrobial agent, and a control unit operatively connected to at least the heat generation unit for controlling the heat generation unit. The device can be a hand-held device and used to apply topical treatment to a treatment area of a subject.

Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters.

The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

A humidifier for a respiratory apparatus for delivering a humidified flow of breathable gas to a patient includes a humidifier chamber configured to store a supply of water to humidify the flow of breathable gas, the humidifier chamber comprising a first heating element configured to heat the supply of water; a relative humidity sensor to detect a relative humidity of ambient air and generate signals indicative of the ambient relative humidity; a first temperature sensor to detect a temperature of ambient air and generate signals indicative of the ambient temperature; and a controller configured to determine an absolute humidity of the ambient air from the signals generated by the relative humidity sensor and the first temperature sensor and to control the first heating element to provide a predetermined relative humidity to the flow of breathable gas. A method of humidifying a flow of breathable gas to be provided to a patient includes determining an absolute humidity of ambient air used to form the flow of breathable gas; and controlling a temperature of a supply of water that humidifies the flow of breathable gas to provide a predetermined absolute humidity corresponding to a predetermined temperature and a predetermined relative humidity of the flow to be delivered to the patient.

An inhaler includes a mouth-piece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalation.

The present invention provides systems, methods, and apparatus for applying a hyperoxic therapy delivery system to a patient; administering hyperoxic gas to the patient according to an oxygen dose-response model; and adjusting the administration of the hyperoxic gas to the patient based upon monitored parameters related to a condition of the patient. Numerous additional features are disclosed.

Systems, apparatuses, and methods for providing negative pressure and/or instillation fluids to a tissue site are disclosed. Some embodiments are illustrative of an apparatus or system for delivering negative-pressure and/or therapeutic solution of fluids to a tissue site, which can be used in conjunction with sensing properties of fluids extracted from a tissue site and/or instilled at a tissue site. For example, an apparatus may comprise a dressing interface or connector that includes a pH sensor, a humidity sensor, a temperature sensor and/or a pressure sensor embodied on a single pad within the connector and proximate the tissue site to provide data indicative of acidity, humidity, temperature and pressure. Such apparatus may further comprise an ambient port for providing the pressure sensor and the humidity sensor with access to the ambient environment providing readings relative to the atmospheric pressure and humidity.

A removable gas sensor module is provided for a therapeutic gas delivery device. The gas sensor module includes a sample chamber which receives a sample gas from the therapeutic gas delivery device. A gas detection unit includes a plurality of sensors operable to measure at least one property of the sample gas. The sensors include two or more of a gas detection sensor, a humidity sensor, a temperature sensor, or a combination thereof. The gas sensor module is self-contained within the therapeutic gas delivery device and swappable with another gas sensor module.

We provide a respiratory therapy system comprising: a flow generator; a humidifier; a respiratory conduit a patient interface coupled to the respiratory conduit to deliver a gases flow to a patient; a sensor configured to determine pressure or flow of the gases flow; a controller configured to control the flow generator to generate the gases flow; and the controller configured to: a) retrieve at least one first signal associated with or indicative of a gases flow and/or pressure in the respiratory conduit; b) determine a measure of at least one first parameter associated with gases flow perturbations and/or pressure perturbations for at least one portion of the retrieved at least one first signal; and c) determine the presence of liquid in the respiratory conduit based at least in part on the measure(s) of the at least one first parameter meeting a first threshold.

The system can be used to reduce or alleviate condensation in a respiratory gas deliver conduit.

Devices and methods for blood flow enhancement and hemodynamic power monitoring are provided. A blood flow enhancement device includes a pump system configured to be coupled to a central vasculature of a subject during cardiopulmonary resuscitation (CPR). The pump system includes a pumping mechanism configured to increase forward blood flow generated during the CPR while substantially limiting backward blood flow generated during the CPR. The pumping mechanism being operated concurrently with the CPR. The hemodynamic power monitor is configured to control a chest compression device and an active valve.

A system for stimulating body tissue may include a stimulation lead, sensors, and a control unit. The stimulation lead may include one or more energy sources. The control unit may include a processor and non-transitory computer readable medium, and an interface (e.g., touch screen interface) for receiving user inputs and communicating information to the user. The sensors may be configured to provide impedance measurements to the control unit. The control unit may calculate lung gas distributions and/or generate an image modeling lung gas distributions. Stimulation delivered by the stimulation may be adjusted based on the impedance measurements.