In one implementation, an amplifier comprises a load circuit comprising a plurality of inductor cells, and a drive circuit configured to receive an input signal, and to drive the load circuit based on the input signal to generate an amplified signal. The amplifier also comprises a controller configured to tune a peaking gain of the amplifier by adjusting a number of the inductor cells that are enabled.

The present disclosure provides circuit and method embodiments for calibrating a signal of an integrated circuit. A programmable resistive element is coupled in series with a node of the integrated circuit, where at least part of the integrated circuit is formed in at least one front end of line (FEOL) device level. The programmable resistive element is formed in at least one back end of line (BEOL) wiring level, and the programmable resistive element is in a non-volatile resistive state that is variable across a plurality of non-volatile resistive states in response to a program signal applied to the programmable resistive element.

A neuron recording system was provided. By using the gain-boosted topology, the amplifier input impedance can be increased while simultaneously reducing the noise. The system can be configured to record local field potentials (LFPs) and neuron spikes, respectively, with low-power consumption. With the flexible digital controller module (DCM), any subset of the recording channels can be activated for recording with independent sampling rate at each channel. A wireless interface to transmit recorded neuron data and an on-chip neuron processor to perform real-time signal processing can be incorporated in the system.

A variable current trans-impedance amplifier (TIA) for an ultrasound device is described. The TIA may be coupled to an ultrasonic transducer to amplify an output signal of the ultrasonic transducer representing an ultrasound signal received by the ultrasonic transducer. During acquisition of the ultrasound signal by the ultrasonic transducer, one or more current sources in the TIA may be varied.