A novel clinical decision support system (CDS) helps the clinician setup, maintain, and interpret aesophageal pressure measurement. The esophageal pressure CDS (Pes CDS) would remind the clinician to do an occlusion test whenever the balloon is first inserted or changes dramatically. It could monitor the occlusion test and provide feedback on the performance and success of the occlusion test. Changes in the patient or monitored data can be tracked by looking for changes in the balloon baseline pressure, changes in the amplitude of the pressure waveform, or changes in the pattern of the Pes waveform. Having information from the ventilator will further increase the ability of the system to determine when Pes is changing unexpectedly.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

The present disclosure describes a system that automatically detects patient-ventilator asynchrony and trends in patient-ventilator asynchrony. The present disclosure describes a framework that uses pressure, flow, and volume waveforms to detect patient-ventilator asynchrony and the presence of secretions in the ventilator circuit.

A patient monitoring, feeding, and mechanical breathing system, the system including an endotracheal probe including a first longitudinal member connected to a first camera and a semi-rigid longitudinal member inserted in an ET tube such that the first camera is aligned with a tip of the ET tube; an OG probe including a second longitudinal member configured to be inserted in an oral gastro (OG) tube, the second longitudinal member including a side camera, configured to be placed facing a window of the OG tube, wherein the side camera includes a tapered side; an enhanced OG probe, including a second camera and a motion sensor placed at the tip of the enhanced OG tube; a device communicatively coupled to the endotracheal, OG and enhanced OG probes, and having a screen configured to display images from any of the first camera, the side camera, and the second camera.

The present disclosure describes a system that automatically detects patient-ventilator asynchrony and trends in patient-ventilator asynchrony. The present disclosure describes a framework that uses pressure, flow, and volume waveforms to detect patient-ventilator asynchrony and the presence of secretions in the ventilator circuit.

Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.

A gastrointestinal tract constricting method according to the present invention aims to constrict the gastrointestinal tract by contracting a desired region of the gastrointestinal tract by a simple and low-invasive procedure. The method includes forming spreading blocks while observing the gastrointestinal tract with an endoscope inserted into the gastrointestinal tract, the spreading blocks being formed at a position between a mucosa layer and a muscle layer and on both sides of a target region, which is to be damaged by a substance, in a circumferential direction of the gastrointestinal tract so that the spreading blocks block spreading of the substance in the circumferential direction of the gastrointestinal tract to prevent spreading of the substance to an outer side of the target region, and supplying the substance to a mucosal surface of the target region or to the position between the mucosa layer and the muscle layer after formation of the spreading blocks.

A suction stent for introduction into a hollow organ of the human or animal body, preferably into the gastrointestinal tract, in particular the intestine, includes a tubular hollow body which is open in the longitudinal direction and made of biocompatible material. The tubular hollow body has a fixed diameter at least in its central portion; and a porous shapeable material, preferably a sponge material, which is biocompatible and shapeable in the radial direction, the porous shapeable material radially sheathing the tubular hollow body at least in a section of the tubular hollow body. Further, a method is provided for sealing a leakage, especially an anastomosis, of the hollow organ.

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure sensing elements which may allow for control of the pressure within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled or room temperature fluid such as water may then be used to rapidly terminate the treatment session.

Methods, systems, and devices are described for fabricating, providing, and using an orogastric tube. The orogastric tube may have, among other things: a proximal end section; a distal end section opposite the proximal end section and having a flexible, resilient curved portion; at least one sump channel extending from the proximal end section along a pre-determined length of the orogastric tube into the distal end section; at least one suction channel extending from the proximal end section along a pre-determined length of the orogastric tube into the distal end section; and optionally at least one balloon channel extending from the proximal end section along a pre-determined length of the orogastric tube to the distal end section. The optional balloon channel is in communication with an expandable balloon in the distal end section; and a main channel encloses a pre-determined length of the sump channel, the suction channel, and, if present, the balloon channel.