A medical device comprising a first tube, a second tube configured to sheath at least a portion of the first tube and configured to translate along a length of the first tube, an expandable device at a distal portion of the first tube, the expandable device having a collapsed state and an expanded state, a patch surrounding at least a portion of an outer surface of the expandable device, and a connector for holding the patch to the expandable device when the second tube covers the patch and the expandable device and for releasing the patch from the expandable device after the second tube uncovers the patch and the expandable device.

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, locating, tracking, monitoring, deflating, and retrieving the same are provided.

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject).

A system for treating internal bleeding via application of a heated irrigant, such that the heated irrigant is delivered at a flow rate of between 2 cc/s and 12 cc/s and at a temperature of between 46 degrees Celsius and 52 degrees Celsius.

Implants comprising electrically-responsive hydrogel are described. Systems to provide electricity to induce response in hydrogel-containing implants are described. Methods for utilizing said system and methods for utilizing said hydrogel-containing implants are described.

The present disclosure is in the field of gastroretentive dosage forms. A gastroretentive dosage form for extended retention in a stomach is provided.

A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).

A rigid hollow tubular adapter releasably attached at a longitudinal nozzle end to a flexible tube during equine nasogastric intubation comprising an annular sleeve having a stationary tubular member and a slidable tubular member. The slidable tubular member is delimited at its ends by the stationary tubular member and a detent member disposed between an equine reflux drainage hole and a longitudinal mouthpiece end. Operator's puffs of airflow through a mouthpiece urges the slidable member to slide toward the detent member closing the equine drainage hole to enable passage of medication into the equine stomach. Equine reflux urges the slidable tubular member to slide toward the stationary tubular member opening the reflux drainage hole to divert equine backflow downwardly through the equine backflow drainage hole preventing passage of equine reflux into the operator's mouth.

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, locating, tracking, monitoring, deflating, and retrieving the same are provided.

Light weight, compact, battery powered, body-worn devices and systems are configured to allow automated, hands-free monitoring and care intervention, such as of an infant, by providing audio and/or physical stimulus when a negative comfort or health condition is detected by the body-worn device and system, and by monitoring the infant's temperature, pulse, and oxygen levels. The body-worn device preferably includes a flexible printed circuit board (“FPCB”) that allows the device to be conformed to the wearer's body, and has a plurality of linear resonant actuators affixed to the FPCB that are configured to impart soothing vibrations from the device to the wearer. A control program is provided and executable on a remote computing device, which control program is configured to enable users (such as a caregiver) to selectively control the actuators. The device may include a water-resistant casing covering its internal components, including the actuators, FPCB, battery, and those portions of on-board sensors not intended for direct monitoring contact with the wearer.