A patient airway dome including an adjustable frame having a hinge such that the hinge allows the frame to adjust between an erected position to create an airway dome and a collapsed position that allows the frame to lay flat, a dome covering located over the retractable frame, a suction port which is connected to a conventional device in order to provide negative pressure to patient airway dome, and an arm access assembly operatively connected to the dome covering, wherein the arm access assembly includes an opening in the dome covering and a closure assembly located adjacent to the opening.

A patient airway dome including an adjustable frame having a hinge such that the hinge allows the frame to adjust between an erected position to create an airway dome and a collapsed position that allows the frame to lay flat, a dome covering located over the retractable frame, a suction port which is connected to a conventional device in order to provide negative pressure to patient airway dome, and an arm access assembly operatively connected to the dome covering, wherein the arm access assembly includes an opening in the dome covering and a closure assembly located adjacent to the opening.

Disclosed is an NGT system, the system comprises a nasogastric tube having a diameter and length configured to pass through an esophagus such that the lumen of the NGT maintains fluid communication with a portion of the digestive tract, and a digestive tract sensor operatively associated with the NGT, the digestive tract sensor configured to sense from inside the body and transmit signals in response to one or both of conditions relating to nourishment states of the digestive tract, and positioning of the NGT.

Provided are devices that are configured for gastric retention for a period of at least six hours (or at least three hours if the subject is in the fasted state) while maintaining their structural integrity and releasing or holding an active or diagnostic agent into or in gastric fluid of a human subject over that period, as well as methods of delivering an agent over an extended period by orally administering such devices to a subject, uses of an enteric polymer in the formation of devices that deliver an agent over an extended period of time, and methods of making such devices.

Actuating components and related methods are generally disclosed. Certain embodiments comprise an actuating component associated with a plurality of microneedles (e.g., for administering a therapeutic agent to a subject). In some embodiments, the actuating component may be administered to a subject such that the plurality of microneedles are deployed at a location internal to the subject (e.g., in the gastrointestinal tract). The actuating component may be contained within, in some embodiments, a capsule (e.g., for oral administration to a subject). In some embodiments, the actuating component has a pre-deployment configuration in which the plurality of microneedles have a first orientation and a deployed configuration in which the plurality of microneedles have a second orientation, different than the first orientation.

A process and unit for determining an estimate for a respiratory signal. Measured values are received, and a sum signal is generated, which is a superimposition of the respiratory signal to a cardiogenic signal. The unit detects heartbeats, and a respective heartbeat time period for each. An intermediate signal is calculated by compensating the influence of the cardiac activity on the sum signal. The unit determines an attenuation signal, which is an indicator of the average time curve of the contribution of the cardiogenic signal to the intermediate signal in a predefined reference heartbeat time period. An intermediate signal section is generated as a section of the intermediate signal in a heartbeat time period and intermediate signal sections are mapped to the reference heartbeat time period. The estimated respiratory signal is calculated with the use of the mapped intermediate signal sections and of the attenuation signal.

A process and unit for determining an estimate for a respiratory signal. Measured values are received, and a sum signal is generated, which is a superimposition of the respiratory signal to a cardiogenic signal. The unit detects heartbeats, and a respective heartbeat time period for each. An intermediate signal is calculated by compensating the influence of the cardiac activity on the sum signal. The unit determines an attenuation signal, which is an indicator of the average time curve of the contribution of the cardiogenic signal to the intermediate signal in a predefined reference heartbeat time period. An intermediate signal section is generated as a section of the intermediate signal in a heartbeat time period and intermediate signal sections are mapped to the reference heartbeat time period. The estimated respiratory signal is calculated with the use of the mapped intermediate signal sections and of the attenuation signal.

Apparatus for performing lavage and suction at a surgical site, the apparatus comprising: a first sleeve having a proximal end, a distal end and a lumen extending from the proximal end to the distal end, wherein the lumen of the first sleeve is configured to receive an endoscope; an irrigation/suction tube mounted to the first sleeve for delivering fluid into, or removing fluid from, the surgical site; a second sleeve having a proximal end, a distal end and a lumen extending from the proximal end to the distal end, wherein the lumen of the second sleeve is configured to receive the first sleeve and an endoscope disposed therein, with the distal end of the first sleeve being movable relative to the distal end of the second sleeve and the distal end of the endoscope; an aft balloon mounted to the second sleeve; an inflation/deflation tube mounted to the second sleeve and in fluid communication with the interior of the aft balloon; a pair of push tubes slidably mounted to the second sleeve; and a fore balloon mounted to the pair of push tubes, such that the fore balloon can be moved relative to the aft balloon.

A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat at least one of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).

A temporary esophagus occlusion device for providing temporary occlusion of the esophagus during intubation of a in patient includes a frame configured to transition between a contracted state, in which it can be swallowed by the patient, and an expanded state, wherein in the expanded state, the frame has a maximum outer diameter sufficient to span an inner diameter of the esophagus of the patient. The device also includes a flexible cover connected to and extending over at least a portion of the frame when the frame is in the expanded state to at least partially block flow of fluid and/or solid materials through the esophagus and a guidewire attached to the frame, sized to be swallowed by the patient along with the frame and having a proximal end portion configured to remain external to the patient's body and a distal end connected to the frame.