The invention discloses an anus cleaner, comprising a bottle body, wherein the inside of the bottle body is a hollow structure; the bottom of the bottle body is provided with a bottle bottom, and the bottle bottom is curved; the center of the bottle bottom is provided with a through hole, and a steel ball check valve is installed in the through hole; the end of the bottle body away from the bottle bottom is provided with a bottleneck, and the bottleneck is provided with threads; the bottleneck is equipped with a cleaning head; the bottom of the cleaning head is provided with threads, and the threads are provided on a mounting table; the mounting table and the bottleneck are matched and connected with the same size; the top of the mounting table is provided with a cleaning neck.

A nozzle for use in delivering a mixture of aerosol propellant and drug formulation. The nozzle includes a drug product inlet configured to receive a mixture of aerosolized propellant and an intranasal dosage form. The inlet is disposed at the proximal end. A nozzle body is secured to the drug product inlet. Two or more channels are disposed within the body. Two or more orifice apertures are disposed at the distal end of the nozzle.

Pressure conditioning systems for supplying insufflation gas to an open-ended body conduit such as a rectal cavity during a transanal minimally invasive surgery (TAMIS) procedure can reduce billowing of walls of the body conduit. A pressure conditioning system can include a pressure storage component, an accumulator, and a flow restrictor. The pressure storage component can include a variable volume reservoir that is biased to a relatively low volume state. The flow restrictor can include insufflation tubing with a restrictor plate having a relatively low diameter orifice. The pressure storage component, accumulator, and flow restrictor can be fluidly connected in various orders in series or as side branches from a gas flow conduit. Despite a pulsed or otherwise discontinuous insufflation gas flow and leakage and absorption from the body conduit, the pressure conditioning system can maintain a constant pressure within the body conduit.

A system comprising a handpiece and drive system configured to removably couple to a proximal end of a housing. A scalpet assembly is configured to removeably couple to the housing, and includes a scalpet array comprising at least one scalpet configured for rotation. The scalpet array is configured to harvest dermal plugs via fractional resection. A collection chamber is configured to collect the dermal plugs, and to house formation of an injectable filler by mincing the dermal plugs, and mixing the dermal plugs with a carrier. The injectable filler is configured for bulk fill. The collection chamber includes a loading port, and a cannular syringe is configured to mate with the loading port to receive the injectable filler, and to deliver the injectable filler for the bulk fill.

The present disclosure relates to a catheter (1) and a method for manufacturing the catheter (1). The catheter (1) comprises a core tube (10) with a lumen (15) extending from a rear end to a front end along an elongation axis (x), a front portion (13) and a rear portion (11). The catheter (1) further comprises a flexible outer layer (20) forming a fluid reservoir (25, 25) containing a fluid between the flexible outer layer (20) and at least a part of the front portion (13). The flexible outer layer (20) optionally comprises one or more radial eyelet(s) (23) arranged in front of the front portion (13) of the core tube (10) and being in fluid communication with the front opening (14), wherein the flexible outer layer (20) is more flexible than the core tube (10). Optionally, the catheter (1) further comprises a flexible inner layer (20).

A proctoscope, comprising a dilator body (2), having a longitudinal axis of extension (X) and internally hollow so as to define an internal volume (V), and at least one handle (5) applied to said dilator body (2), wherein the dilator body (2) has a distal portion (2a), having a substantially tubular shape and defining a zone of dilation of an internal cavity of a patient, and a proximal portion (2b) extending from the distal portion (2a) in a diverging fashion and defining a rear opening (4) for accessing said internal volume (V), wherein said distal portion (2a) of the dilator body (2) has at least one front opening (3) to enable access to the patient's mucosa or tissue from said internal volume (V), and wherein said diverging proximal portion (2b), or, alternatively, said at least one handle (5), has an anchorage means (6) for an adaptor body (100) suitable for placing a detection device (200) in a position such as to detect the internal volume of the proctoscope (1). Said dilator body (2) has, on said diverging proximal portion (2b), at least one auxiliary access opening (7) configured to enable the insertion of a means for operating in the internal volume (V) through said auxiliary opening (7) in a configuration wherein the proctoscope (1) is associated with said adaptor body (100).

A rectal injection device and a method of operating the same. In one embodiment, the device includes: (1) a body having a handle, (2) a suction system associated with the body, (3) a trigger associated with the handle, (4) a pod coupled to the body via a neck and (5) multiple suction ports associated with the pod, each of the multiple suction ports configured to receive a ligation band thereabout, the suction system configured to provide a suction to the multiple suction ports to draw tissue thereinto, the pod configured to deploy the ligation bands upon activation of the trigger.

The device (10, 36, 38, 42, 68) applies a negative pressure to an endoluminal surface in the body of a patient to facilitate healing of a wound in the endoluminal surface. The device comprises a flexible porous element (14) with a peripheral outer face (32) for contact with the wound, the outer face being defined between opposite proximal and distal ends of the porous element. A suction tube (30) for being connected to a suction source externally of the patient's body is provided in fluid communication with the porous element to apply a negative pressure to the wound via the outer face (32) of the porous element (14) upon operation of the suction source. The porous element (14) has at least one through passageway (16) extending from its proximal end to its distal end for passage of bodily substances of the patient through the porous element. The device can also include a drainage tube (22) for collection and drainage of the bodily substances from the patient, wherein the drainage tube is received in the through passageway of the porous element. The device is particularly suitable for assisted healing of anastomotic wounds but its use is not limited thereto.

A drug delivery system is provided that has an adjustable dose mechanism allowing setting and locking the dose then administration of the set dose. A method for administering a medicament using the drug delivery system is also provided.

A system comprising a handpiece and drive system configured to removably couple to a proximal end of a housing. A scalpet assembly is configured to removeably couple to the housing, and includes a scalpet array comprising at least one scalpet configured for rotation. The scalpet array is configured to harvest dermal plugs via fractional resection. A collection chamber is configured to collect the dermal plugs, and to house formation of an injectable filler by mincing the dermal plugs, and mixing the dermal plugs with a carrier. The injectable filler is configured for bulk fill. The collection chamber includes a loading port, and a cannular syringe is configured to mate with the loading port to receive the injectable filler, and to deliver the injectable filler for the bulk fill.