The present invention relates to a noninvasive electrical stimulation method and device, and the noninvasive electrical stimulation method includes the steps of: arranging first and second electrodes for applying electrical stimulation to a human body and first and second magnetic materials to thus allow the first and second magnetic materials to generate a magnetic field in a direction crossing the direction of an electric current between the first and second electrodes; and controlling at least one of a crossing angle (θ) at which the electric current between the first and second electrodes and the magnetic field generated by the first and second magnetic materials cross each other and the strength (B) of the magnetic field generated by the first and second magnetic materials.

Tumor treating fields (TTFields) can be delivered to a subject's body at higher field strengths by switching off one or more electrode elements that are overheating without switching off other electrode elements that are not overheating. This may be accomplished using a plurality of temperature sensors, with each of the temperature sensors positioned to sense the temperature at a respective electrode element; and a plurality of electrically controlled switches, each of which is wired to switch the current to an individual electrode element on or off. A controller input signals from the temperature sensors to determine the temperature at each of the electrode elements, and controls the state of the control input of each of the electrically controlled switches to selectively switch off the current or adjusted the duty cycle at any electrode element that is overheating.

An electroconductive rubber sheet includes a sheet-shaped rubber base material having electrical conductivity and an electroconductive sheet embedded in the rubber base material. This electroconductive rubber sheet can be obtained according to a method for producing an electroconductive rubber sheet that includes, for example, a step of placing an electroconductive sheet and a sheet-shaped rubber material, which has electrical conductivity and an opening in a central portion of the sheet-shaped rubber material, on a mold and a step of pressing the electroconductive sheet and the rubber material at a temperature at which the rubber material is softened.

A medical device control unit is provided. The control unit may include at least one processing device, a circuit electrically coupled to the at least one processing device, and a flexible housing configured to contain the at least one processing device and the circuit. The flexible housing may include at least one connection portion configured to engage a connector protruding from a flexible carrier, and at least one electrical contact electrically coupled to the circuit and configured to establish an electrical connection with an exposed electrical contact on the flexible carrier when the connection portion is engaged with the at least one connection portion.

An apparatus for non-invasive directional tissue treatment comprises an energy source and an array of energy delivery elements placed in a predetermined order defining a tissue treatment area such that tissue tightening obtained is higher in a first direction than in a second direction of the two-dimensional array.

A lead assembly for networked implants may contain a controller, an implantable tissue contact system connected to the controller and including a plurality of leads, and a breakout connector connected to each of the plurality of leads, and further connected to a shared communication path. A physiological interface system may contain a controller and an implantable tissue contact system. Methods of treating a subject and monitoring a subject include transmitting signals between a controller and an implantable tissue contact system.

An electrode array includes a body portion, at least one tail portion, at least one tissue surface contact, and at least one intratissue contact. The electrode array can provide stimulation or record signals from both the surface of a target tissue and within the target tissue. A system for tissue surface and intratissue signal recording and/or stimulation contains an electrode array, a controller or receiver, and at least one connection between the electrode array and the controller or receiver. A method of recording signals and/or stimulating tissue includes contacting the target tissue surface and target tissue interior with an electrode array and providing or recording an electrical, chemical, or optical signal.

An implantable apparatus can be positioned in a body of a patient. The implantable apparatus can comprise a plurality of stimulation zones that are configured to provide tumor treating fields to a target site in one or a plurality of sequences that apply differential stimulation amplitudes and electric field directions relative to the target region in the body, thereby optimizing the treatment efficacy to kill tumor cells in a solid tumor or stray tumor cells in the peripheral area surrounding the tumor.

The present invention relates to a medical device and a method for assessing and monitoring epithelial barrier function in vivo of a subject using electrical impedance measurements. The method comprises initiating an impedance measurement session including passing an electrical current through the skin of the subject to obtain values of skin impedance of a target tissue region, said data comprising at least one impedance value measured in the target tissue region at different tissue layers. Further, an evaluation procedure is applied for analyzing the epithelial barrier function in the target tissue region based on the measured data set of impedance values for the target tissue region at different tissue layers. The procedure evaluates the obtained data set of impedance values to provide an outcome indicating a status of the epithelial barrier function of the subject.

Systems and methods are described herein for determining whether a patient's cardiac conduction system or portions thereof are engaged by cardiac conduction system pacing therapy. One or more local metrics of electrical heterogeneity information may be generated based on surrogate cardiac electrical measured using a plurality of local external electrodes, which may be used to determine whether the patient's cardiac conduction system is engaged.