A method for spinal cord stimulation treatment includes positioning eight implantable electrodes to a dura matter in an epidural space proximate to a subject's spinal cord so that (i) a first circuit is created between a first and second electrode on a first channel, (ii) a second circuit is created between a third and fourth electrode on a second channel, (iii) a third circuit is created between a fifth and sixth electrode on a third channel, and (iv) a fourth circuit is created between a seventh and eighth electrode on a fourth channel, transmitting signals through the first and second circuits that interfere to produce a first beat signal, transmitting signals through the third and fourth circuits that interfere to produce a second beat signal, and interaction of the first and second beat signals results in a combined beat signal proximate to the subject's spinal cord.

A connector assembly includes a lead with a lead body having proximal and distal portions. The lead body defines a longitudinal axis. Terminals are disposed along the proximal portion and a proximal tip is attached thereto. The proximal tip defines an aperture that is non-parallel to the longitudinal axis. The connector assembly further includes a connector having a connector body, a connector lumen, and connector contacts disposed within the connector body. The connector body includes a fastener aperture proximal to all of the connector contacts and intersecting the connector lumen. The fastener aperture and the aperture of the proximal tip align when the proximal portion is fully received within the connector lumen. At least one of the apertures includes internal threading. The connector assembly also includes a threaded fastener for insertion into the apertures to secure the lead to the connector.

A connector assembly includes a lead with a lead body having proximal and distal portions. The lead body defines a longitudinal axis. Terminals are disposed along the proximal portion and a proximal tip is attached thereto. The proximal tip defines an aperture that is non-parallel to the longitudinal axis. The connector assembly further includes a connector having a connector body, a connector lumen, and connector contacts disposed within the connector body. The connector body includes a fastener aperture proximal to all of the connector contacts and intersecting the connector lumen. The fastener aperture and the aperture of the proximal tip align when the proximal portion is fully received within the connector lumen. At least one of the apertures includes internal threading. The connector assembly also includes a threaded fastener for insertion into the apertures to secure the lead to the connector.

Implementations described and claimed herein provide thin film devices and methods of manufacturing and implanting the same. In one implementation, a shaped insulator is formed having an inner surface, an outer surface, and a profile shaped according to a selected dielectric use. A layer of conductive traces is fabricated on the inner surface of the shaped insulator using biocompatible metallization. An insulating layer is applied over the layer of conductive traces. An electrode array and a connection array are fabricated on the outer surface of the shaped insulator and/or the insulating layer, and the electrode array and the connection array are in electrical communication with the layer of conductive traces to form a flexible circuit. The implantable thin film device is formed from the flexible circuit according to the selected dialectic use.

Disclosed herein are methods and systems for clinical practice of medical imaging on patients with metal-containing devices, such as implanted cardiac devices. In particular, Disclosed herein are methods and systems for improved late gadolinium enhancement (LGE) MRI for assessing myocardial viability for patients with implanted cardiac devices, i.e., cardiac pacemakers and implantable cardiac defibrillators.

Disclosed herein are methods and systems for clinical practice of medical imaging on patients with metal-containing devices, such as implanted cardiac devices. In particular, Disclosed herein are methods and systems for improved late gadolinium enhancement (LGE) MRI for assessing myocardial viability for patients with implanted cardiac devices, i.e., cardiac pacemakers and implantable cardiac defibrillators.

Devices and methods for manipulating devices such as micro-scale devices are provided. The devices can include a tether of various materials surrounded by a stiff body. The tether interfaces with microscale devices to draw them against the stiff body, holding the microscale devices in a locked position for insertion into or extraction out of tissue. The tensional hook and stiff body are configurable in a multitude of positions and geometries to provide increased engagement. Such configurations allow for a range of implantation and extraction surgical procedures for the device within research and clinical settings.

A system and method for restoring inspiratory muscle function to restore breathing and expiratory muscle function to restore an effective cough in the same individual, wherein the systems that selectively activate the inspiratory or expiratory muscle function are separately ground to limit or prevent the flow of electrical current to both the expiratory and inspiratory muscles at the same time and to avoid damaging either neuromuscular system. Also described is the method by which the inspiratory or expiratory muscles are activated selectively to optimize the action of the inspiratory muscles to restore breathing and to optimize the action of the expiratory muscles to restore cough.

Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one component designed to cause dyssynchrony of the right ventricle, and a controller configured for adjusting the function of the at least one component based at least in part on sensor data from the at least one sensor.

A method of imaging an implant device in a computing device is provided. The computing device includes a processor interconnected with a memory and a display. The method includes, at the processor: obtaining a first magnetic resonance (MR) image of a patient tissue, the first MR image containing a first magnetic field strength indicator; responsive to the implant device being inserted in the patient tissue, obtaining a second MR image of the patient tissue, the second MR image containing a second magnetic field strength indicator smaller than the first magnetic field strength indicator; registering the second MR image with the first MR image; generating a composite image from the first MR image and the second MR image; and presenting the composite image on the display.