The present invention relates to a microcurrent generator capable of generating microcurrents by utilizing a gap between different metals and obtaining a healing effect by using the generated microcurrents. The present invention relates to a configuration of generating microcurrents by forming a gap (G) between a first metal (10) and a second metal (20) made from different materials.

The invention provides the use of electrical pulses (I, W) to reduce, improve, heal or prevent recurrence of a chronic ulcer, comprising administering to a need (1, 2, 3) an effective amount of an electric stimulation in multiple treatment sessions, wherein the electric stimulation stimulates the lymphatic system.

Apparatuses, systems and methods of treating a vertebrate organism via application of signals in a manner that enhances biological function. The signals applied can be produced by an electronic circuit, and can comprise magnetic fields emitted via one or more coil emitter devices.

A diagnostic system is provided that provides sensing and transmitting of fusion indicia to determine whether fusion has occurred. In some embodiments, a diagnostic system comprises a spinal implant or graft material; an antenna configured for sending signals to a remote location; a sensor configured for measuring at least one fusion indicia; and a receiver for receiving signals at the remote location.. In some embodiments, a method of utilizing a diagnostic system comprises the steps of inserting a spinal implant or graft material within a disc space between two vertebrae; measuring at least one fusion indicia; sending signals to a remote location with an antenna; and receiving signals with a receiver at the remote location.

Disclosed herein are compositions comprising containers and silk elements. Disclosed herein are methods of regenerating an at least partially severed nerve cell. Disclosed herein are compositions for regenerating an at least partially severed nerve cell.

A system and method for spinal fusion that can include: a spinal cage body that includes at least one defined graft window cavity; a plurality of electrodes exposed on the surface of the spinal cage body; control circuitry configured to drive the plurality of electrodes in a stimulation mode; wherein there is at least a targeted osteoinduction region and a targeted non-osteoinduction region that are immediately adjacent to the spinal cage body; and wherein the control circuitry includes configuration to excite the plurality of electrodes during the stimulation mode for generation of a current density in the targeted osteoinduction region and targeted non-osteoinduction region according to targeted levels of bone growth.

The present invention provides a system and method for measuring the impedance of one more target cells before and after an electroporation protocol has been applied to the cells. The result of the impedance measurement provides a feedback control that can be implemented during and/or after the electroporation protocol to customize the electrical treatment for a particular target cell or cellular tissue.

Techniques for treating a tumor and vaccinating against cancer are described. The techniques include treating the tumor by positioning electrodes over an interface between the tumor and non-tumor tissue and applying sub-microsecond pulsed electric fields. The positioning is facilitated by an imaginary contour line of a threshold value of the electric field. In an example, the imaginary contour line is overlaid over images that include the tumor such that the electrodes are properly positioned over the tumor. The techniques also include vaccinating against cancer by passing sub-microsecond pulsed electric fields through tumor cells of a subject sufficient to cause the tumor cells to express calreticulin on surface membranes. The tumor cells are extracted and introduced with the expressed calreticulin into the subject or another subject, thereby providing a vaccination.

The present disclosure belongs to the field of treatment devices, and specifically relates to a medicated thread drainage treatment device. The treatment device includes a first treatment unit used for postoperative pain relief and drainage; a second treatment unit used for promoting quick healing of a wound; a third treatment unit used for preventing deep venous thrombosis; and an electropneumatic, negative-pressure, electric stimulation multipurpose therapy apparatus connected with the first treatment unit, the second treatment unit, and the third treatment unit and providing electropneumatic pressure, negative pressure, and electric energy. The present disclosure is used for postoperative quick healing and recovery; promotion of clinical use guidelines will greatly reduce and even eliminate the postoperative complications, particularly postoperative complications of pulmonary embolism, thus saving patients' lives.

A system and method for pulsed electromagnetic fields (PEMF) tissue engineering enhances musculoskeletal tissue stimulation. A tissue engineering device may include both low and high pulse frequency signal generation components that may alternatively drive one or more coils to generate PEMFs. These PEMFs may be applied to bone tissue, tendons, ligaments, and/or cartilage. A prescribed treatment regimen using the tissue engineering device may include a first period of time where a first pulse frequency is used in treatment that supports tissue proliferation followed by a second period of time where a second pulse frequency (less than the first pulse frequency) is used in treatment that supports tissue differentiation. A treatment regimen may also include, with the frequency characteristic, applying a slew rate to the pulse characteristics that is on the order of around 30 to 100 Tesla per second to drive tissue differentiation in a targeted manner.