An ElectroConvulsive Therapy (ECT) device for generating a series of electrical therapeutic pulses for delivery to a patient to cause a seizure includes a user interface configured to accept one or more therapy settings from a user, a therapy generator configured to generate the series of electrical therapeutic pulses, and a therapy delivery system structured to apply the series of electrical therapeutic pulses to the patient. The ECT device further includes a power monitor configured to measure average electrical power that is being delivered to the patient through the series of electrical therapeutic pulses in real-time during a treatment session, and to cause the therapy generator to cease operation after a predetermined threshold level of average electrical power has been delivered to the patient. Related methods are also disclosed.

An ElectroConvulsive Therapy (ECT) device for generating a series of electrical therapeutic pulses for delivery to a patient to cause a seizure includes a user interface configured to accept one or more therapy settings from a user, a therapy generator configured to generate the series of electrical therapeutic pulses, and a therapy delivery system structured to apply the series of electrical therapeutic pulses to the patient. The ECT device further includes a power monitor configured to measure average electrical power that is being delivered to the patient through the series of electrical therapeutic pulses in real-time during a treatment session, and to cause the therapy generator to cease operation after a predetermined threshold level of average electrical power has been delivered to the patient. Related methods are also disclosed.

The present disclosure relates to methods and devices for applying electromagnetic field jerk to materials and tissues.

A first method comprises the following steps: A) generating an activation signal having a waveform that generates electromagnetic field jerk; and B) applying the activation signal to the arrangement of electromagnetic transducers.

A second method comprises the following steps: a) generating a carrier signal with a series of pulses by a computing unit; b) generating a modulating signal that generates jerk; c) generating an activation signal that modulates the carrier signal using the modulating signal that generates jerk; d) applying the activation signal to the arrangement of electromagnetic transducers.

Some embodiments of the disclosed methods and devices are used for fracturing, pulverizing and reducing particle size of material and tissues.

A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.

A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.

In some examples, a medical device system includes an electrode. The medical device system may include impedance measurement circuitry coupled to the electrode, the impedance measurement circuitry may be configured to generate an impedance signal indicating impedance proximate to the electrode. The medical device system may include processing circuitry that may be configured to identify a first component of the impedance signal. The first component of the impedance signal may be correlated to a cardiac event. The processing circuitry may be configured to determine that the cardiac event occurred based on the identification of the first component of the impedance signal.

An external defibrillator apparatus (10, 74) operates to deliver electrical shocks to the heart muscles of a patient using a self-contained piezoelectric power source. The apparatus has a body (12) which includes a handle portion (26) in fixed operative connection with disposed paddle portions (14, 16). Each paddle portion includes a respective electrode (22, 24). Manual movement of a trigger (28, 78) is operative to cause circuitry (32, 82) which includes a piezoelectric crystal (34) to develop sufficient electrical potential between the electrodes to deliver the electrical shocks to the heart muscles through external contact with the patient's chest.

The present invention relates to methods for treating a depression condition in a subject, including administering to the subject at least one microglial modulator or a combination thereof. Further provided are methods using a microglial modulator(s) in combination with non-invasive brain stimulation (NIBS), such as electroconvulsive therapy (ECT).

An implantable medical device (IMD) includes a heterogeneous housing configured to receive and store one or more components of the IMD. The housing includes an intrinsically non-conductive and non-magnetic base material and at least one dopant with a property of at least one of electrical conductance and magnetic permeability. The base material and the dopant form a first region of the housing including a first skin depth and a second region of the housing including a second skin depth different than the first skin depth.

In some examples, a medical device system includes an electrode. The medical device system may include impedance measurement circuitry coupled to the electrode, the impedance measurement circuitry may be configured to generate an impedance signal indicating impedance proximate to the electrode. The medical device system may include processing circuitry that may be configured to identify a first component of the impedance signal. The first component of the impedance signal may be correlated to a cardiac event. The processing circuitry may be configured to determine that the cardiac event occurred based on the identification of the first component of the impedance signal.