The present technology provides regenerative treatment methods and apparatus to promote regeneration of target biological tissue. Regenerative treatments include the subcutaneous and cutaneous application of carbon dioxide. Regenerative treatment methods include an initial treatment phase and a maintenance treatment phase. Regenerative treatment apparatus include effervescent mineral compositions for cutaneous application of carbon dioxide.

The present technology provides regenerative treatment methods and apparatus to promote regeneration of target biological tissue. Regenerative treatments include the subcutaneous and cutaneous application of carbon dioxide. Regenerative treatment methods include an initial treatment phase and a maintenance treatment phase. Regenerative treatment apparatus include effervescent mineral compositions for cutaneous application of carbon dioxide.

The present disclosure provides methods and systems for limiting arcing during an electroporation procedure. A method includes delivering a calibration shock using a catheter, measuring a current delivered during the calibration shock and a voltage delivered during the calibration shock, calculating, using a processing device, a calibration shock impedance based on the delivered current and the delivered voltage, calculating, using the processing device, a bridge impedance based on the calibration shock impedance and a target impedance, wherein the bridge impedance is a difference between the calibration shock impedance and the target impedance, adding an impedance in series with the catheter, the impedance being greater than or equal to the bridge impedance, and delivering a therapeutic shock using the catheter in series with the added impedance.

A system and method for reducing and preventing head injuries using a combination of hardware and software. Elevated neck stiffness can be learned through the system, device, and the method described in the present invention by delivering and pairing a certain appropriate sensory cue (SnC) with a certain appropriate significance cue (SgC). the system, device, and method are used to generally facilitate and validate an increase in neck stiffness to prevent or reduce the likelihood of concussion upon impact. The system employs a combination of hardware and software, such as using modified virtual reality (VR) headsets (in both hardware and software), to deliver visual, auditory, and other cues (somatosensory, vestibular, etc.) as SnC. The system also employs a combination of hardware and software, such as using modified virtual reality (VR) headsets (in both hardware and software), to deliver somatosensory, vestibular, visual, auditory, and other cues as SgC.

A system and method for reducing and preventing head injuries using a combination of hardware and software. Elevated neck stiffness can be learned through the system, device, and the method described in the present invention by delivering and pairing a certain appropriate sensory cue (SnC) with a certain appropriate significance cue (SgC). the system, device, and method are used to generally facilitate and validate an increase in neck stiffness to prevent or reduce the likelihood of concussion upon impact. The system employs a combination of hardware and software, such as using modified virtual reality (VR) headsets (in both hardware and software), to deliver visual, auditory, and other cues (somatosensory, vestibular, etc.) as SnC. The system also employs a combination of hardware and software, such as using modified virtual reality (VR) headsets (in both hardware and software), to deliver somatosensory, vestibular, visual, auditory, and other cues as SgC.

The present disclosure provides a method of preventing or treating depression in a subject in need thereof, including administering to the subject an effective amount of benzoic acid or a salt and derivative thereof. Also provided is a composition for use in preventing or treating depression in a subject in need thereof.

An ECT system capable of focusing the electrical signals on a specific portion of the patient's brain is provided. The ECT system includes a means of applying unidirectional electrical signals and asymmetric electrodes for focusing the signals on the patient. A method of titrating an electro-convulsive therapy (ECT) system and a method of operating an ECT system are also provided. The method includes setting an initial current value, administering an ECT signal to the patient, determining if the seizure threshold has been achieved, and repeating as necessary until the seizure threshold is achieved.

An ECT system capable of focusing the electrical signals on a specific portion of the patient's brain is provided. The ECT system includes a means of applying unidirectional electrical signals and asymmetric electrodes for focusing the signals on the patient. A method of titrating an electro-convulsive therapy (ECT) system and a method of operating an ECT system are also provided. The method includes setting an initial current value, administering an ECT signal to the patient, determining if the seizure threshold has been achieved, and repeating as necessary until the seizure threshold is achieved.

Systems, methods, and articles are disclosed for the behavioral treatment of an individual. One embodiment comprising a wearable housing assembly further comprising a microcontroller, charging jack port, status monitor, selection element, sensor array, and deterring member attached to the user via a connection strap, adjustment belt, frame, prong, and adjustment hole. The user selects the input/output properties of the microcontroller, status monitor, sensor array, and deterring member using the selection element. Upon performing an undesirable emotional outburst, the user is automatically administered a deterrence element, causing the cognizance of, or the inability to engage in, the undesirable behavior. Other embodiments are described and shown.

Techniques are disclosed for modulating the generation of charge current by operational circuitry included in an implantable medical device (IMD) for delivery of an induction stimulation pulse waveform by the IMD. The modulation may include modulating a charging circuit of the operational circuitry to facilitate the regulation of the induction stimulation pulse waveform. The techniques include monitoring an electrical parameter of a charging path during the delivery of the induction stimulation pulse and modulating the charging circuit based on the monitored electrical parameter.