A method for sterilizing viruses comprises generating a beam having radiating energy therein at a predetermined frequency for generating mechanical eigen-vibrations in a spherical virus to destroy the spherical virus and a predetermined cartesian beam intensity for imparting transverse shear forces to an icosahedral lattice structure of the spherical virus to destroy the icosahedral lattice structure of the spherical virus using beam generation circuitry. A resonance frequency of the spherical virus for inducing the mechanical eigen-vibrations in the spherical virus is determined based upon a size, geometry, and protein material of the spherical virus using a predetermined three-dimensional acoustical model of mechanical vibrations within the spherical virus. The beam generation at the predetermined frequency and the predetermined cartesian beam intensity is controlled using a controller responsive to the determined resonance frequency. The predetermined frequency equals the resonance frequency of the spherical virus. The beam on is radiated a predetermined area to destroy the spherical virus at the predetermined area using radiating circuitry. The mechanical eigen-vibrations at the resonance frequency of the spherical virus determined by the predetermined three-dimensional acoustical model are induced within the spherical virus to destroy the spherical virus responsive to the predetermined frequency. The transverse shear forces are imparted to the icosahedral lattice structure of the spherical virus to destroy the icosahedral lattice structure of the spherical virus.

Provided is a mouthpiece which is mounted in an oral cavity for use in changing the shape of the skull including the maxillary bone and is composed of a plurality of segment pieces, at least some of the segment pieces being configured to approach or be spaced apart from each other by means of a screw, wherein the surfaces of the segment pieces facing or contacting the skin in the oral cavity are configured such that the segment pieces overlap with each other, such that a gap does not occur in spite of the approaching or spacing-apart movement of the segment pieces relative to each other.

A radiation treatment device comprises a radiation source layer comprising a radiation source and a controller. The radiation source is configured to emit radiation with a wavelength in the range 822 nm to 1322 nm. In a preferred embodiment, the device configured to emit radiation with a wavelength of 1067 to 1077 nm.

Embodiments of an improved photodynamic therapy device are provided. An example of the device includes an irradiation head having a first end and a surface at a second end, the surface having a radius of curvature. The device also includes a plurality of light sources disposed on the curved surface. The plurality of light sources are configured to emit light having at least one wavelength corresponding approximately to an excitation peak of at least one photosensitizer. The light emitted by the plurality of light sources is focused to a focal point based on the radius of curvature of the surface and a target surface (e.g., a corneal surface of an eye) may be positioned at the focal point for treatment.

The present disclosure features systems and devices for robotic debridement and perforating of finger- and toenails, as well as methods of use of the same. The systems and devices may be used for in the treatment of fungal infection of the nail, as well as for cosmetic uses, e.g., pedicure and manicure.

An assembly for redirecting light emitted by an end-emitting optical fiber into an inner lumen of a body is provided. According to one implementation, the body includes one or more surfaces disposed on or in the body onto which the light is configured to impinge when the end emitting optical fiber is activated, the one or more surfaces being configured to alter the trajectory of the light so that the light is directed to impinge on a light reflector of a cap removably attached to the body, the light reflector of the cap being configured to redirect the light distally into the inner lumen of the body.

Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.

The present invention provides for devices and methods of treating wounds, including general wounds, gum disease and gingival tissues post scaling/root planning, using a diode laser which generates a beam of light having a wavelength in the visible portion of the electromagnetic spectrum (400 nm-700 nm). Further disclosed are devices and methods capable of stimulating tissue regeneration at the site of a wound.

The present application relates to a cold plasma device (1) for treating skin (5). The cold plasma device (1) comprises a cold plasma generator (3) adapted to generate cold plasma that produces reactive species for treating said skin (5), and a manipulator (10) adapted to manipulate said skin (5) to increase exposure of bacteria on said skin to said reactive species during use of the device.

The present invention relates to a composition and a kit of parts for antimicrobial photodynamic therapy and uses of the same, the composition comprising (a) hydrogen peroxide, carbamide peroxide and/or sodium hypochlorite and (b) at least one photosensitizer capable of being activated by light emitted in the blue spectrum, in particular curcumin, riboflavin and erythrosine.